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10 Cards in this Set

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Herpes simplex virus

HSV-1 usually produces oral labial lesions whereas hsv-2 usually causes genital lesions. The virus spreads through epidermal cells causing them to fuse into giant cells. It is a recurrent vesicular eruption which is painful.



attacks the muccocutaneous urfaces due to infection. Inflammatory response leads to erythema and swelling.

How is the initial infection passed on

Buy direct contact after which the herpes virus remains dormant in local nerve ganglia. Primary episodes are generally longer and more severe than reoccurrences.

The onset of hsv is preceded by

Prodromal symptoms such as


tingling


burning or


pain



but can also present with lymphadenopathy


fever


discomfort


malaise and


edema of involved tissue.

Dermatitis herpetiformis

Looks like herpes simplex virus but is not caused by HSV.



Consists of pruritic papules and vesicles on the elbows knees buttocks neck and scalp.



It is associated with celiac disease in 15 to 25%.



treat with dapsone and a gluten-free diet.

HSV-1 example

Cold sore

What is HSV-1 triggered by?

Sun, stress and fever

Hsv-2 examples

Genital vesicles and blisters on a red base


Unilateral, less pain in reoccurence

Diagnosis of herpes simplex virus

By clinical picture.



Multinucleated giant cells on tzank smear.

Treatment of Hsv

Oral or IV Acyclovir for severe cases or for immunocompromised.



Daily treatment with acyclovir vancyclovir famciclovir or



suppressive therapy may be used in patients with greater than 6 outbreaks per year or for those with Erythema multiforme.

Herpes simplex virus and AIDS

When HSV last greater than 1 months it can be considered an aids-defining illness