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13 Cards in this Set

  • Front
  • Back

Heredity

The passing down of traits from parents to their offspring.

Inheritance

The process of these traits being passed down from parents to their offspring.

Phenotype

Observable traits.

Experiments that discovered DNA

Griffith- Bacteria phages convinced biologists that a specific kind of molecule was the root of genetic inheritance. As he carried out this experiment on rats any inducing/injecting bacteria cells in them. He came to the conclusion that chemical substances (DNA and proteins) from one cell are capable of genetically transforming another cell.

DNA

encodes genetic information

Experiments that

Hershey and Chase performed other bacterial phage experiment, and their results convince the scientific world that DNA was the genetic hereditary material.


They carried out this experiment.


To figure out the structure of DNA and how this structure enables the molecule to store genetic information and transmit it from parents to offspring.


Steps: 1. Infection


2. Blending


3. Centrifugtion

Structure of nucleotides

Cytosine


Adenine


Guanine


Thymine


Uracil (in RNA ONLY)

Structure of nucleotides

Contain


A phosphate group attached to a sugar with any of the 4 nitrogenous bases (either adenine, guanine, cytosine, thymine and uracil in RNA)

DNA consists of

Antiparallel DNA strands that coil to form a double helix. With sugar, phosphate group and nitrogenous bases attached to its backbone.

Two parts of DNA used for coding of genetic material

the third and fifth carbon atoms of adjacent sugar rings. These are known as the 3′-end (three prime end), and 5′-end (five prime end) carbons.


DNA Damage

Endogenous


Exogenous

Exogenous Damage

caused by external agents


such as:


•ultraviolet radiation from the sun


•other radiation frequencies, including x-rays and gamma rays


•hydrolysis


• viruses

Endogenous damage

Caused by attacks such as


by


reactive oxygen species produced from normal metabolic byproducts (spontaneous mutation), and


replication errors