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20 Cards in this Set

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  • Back
What is the purpose of herd level testing?
determine if the herd is positive or negative for a disease
What is a herd level test?
evaluation of a sample (or all) of the animals in a herd to classify the herd as positive or negative
Are pooled samples from different herds classified as a herd level test?
No, because it isn't specific for one particular herd then
What is herd level sensitivity?
the probability that a positive herd gives a positive test result
What is herd level specificity?
the probability that a negative herd gives a negative test result
What are herd level sensitivity and specificity dependent on?
number of animals tested
true prevalence in the herd
herd cutoff value for positive/negative
diagnostic sensitivity and specificity
What is a herd level PPV and herd level NPV?
HPPV is the probability that a test positive herd is truly positive
HNPV is the probability that a test negative herd is truly negative
What is the purpose of sampling?
provide an unbiased estimate of the variable being investigated in the population
What is a target population?
population to which the test results of a sample will be extrapolated
Why is random sampling important?
allows inferences to be made about the entire herd or population based on the tests of some individuals
What is simple random sampling?
all animals are included, and a random number generator or similar technique is used to choose which animals to sample
What is systematic random sampling?
The first animal sampled is random, then every nth animal is sampled
What is a disadvantage of systematic random sampling?
some animals may not be included because they don't go through the chute etc
What is stratified random sampling?
samples of subgroups within a herd are chosen based on what portion of the total they represent
*use simple random sampling within each subgroup
What are the major types of non-random sampling?
haphazard
convenience
targeted
What type of sample should be used to estimate prevalence?
random sample
What type of sample should be used to determine the presence of a disease?
random or targeted sample
What things are required to estimate prevalence in a herd?
max tolerable error of the estimate
reliability coefficient
true prevalence estimate
test accuracy (Se, Sp)
What is the maximum tolerable error?
how large of an error one is willing to allow in the prevalence estimate
How would you adjust the sample size needed if the herd is finite?
alter denominator
use the adjustment when n>0.05N