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15 Cards in this Set

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Cynara scolymus
AC: Caffeoylquinic acids; chlorogenic acid and Cynarin
Artichoke indication
i. Digestive complaints (eg. stomach ache, nausea, vomiting, flatulence
ii. Adjuvant to a low fat diet in the treatment of mild to moderate hyperlipidemia
i. For lowering serum cholesterol, 1800 to 1920 mg/d in 2 to 3 divided doses
ii. The isolated constituent cynarin 60-1500 mg per day has been used to for cholesterol
Crataegus species; C. monogyna, C. laevigate
Missori State flower
Hawthorn active ingridient
Rutin and vitexin
Vitexin : flowers and leaves : high in flavonoids and Fruits : contain lowest
Hawthorn standardization
international standardization recommendations range from 0.6~ 1.5% flavnoids, typically calculated as hypersosides
preperations based on hydroalcohoic extracts
Hawthorn are indicated for
Class II as defined by the NYHA
Compared to capropiril: no sig. difference. very well tolorated.
Antioxidant, anti-inflammatory, astringent, cardioprotective, protect cell membranes
dosing of hawthorn
i. The dosage range recommended in review literature is 160-900 mg hawthorn extract per day in 2-3 divided doses (corresponding to 3.5-19.8mg flavonoids or 30-168.8mg oligomeric procyanidines). Some sources recommend a range of 240-480mg/day for extracts standardized to 18.75% oligomeric procyanidines
Horse Chestnut
(SN: Aesculus hippocastanum)
Active compounds of Horse chestnut
i. Terpenoid; Escin and Aescin
ii. Fatty acids (eg. Myristic, stearic, oleic and lauric acids)
iii. Coumarin derivatives (eg. Aesculin, from the bark, leaves, twigs)
Horse chestnut standarization
standardized to contain 16-20% triterpene glycosides calculated as escin (aescin) content
Horse chestnut indication
i. Treatment of chronic venous insufficiency (trial evidence)
ii. As an antiedemic
iii. Treatment of inflammatory conditions (sport injuries)
iv. Skin care products (cellulitis)
v. Treatment of hemorrhoids
Horse chestnut clinical stuies comparing compression stocking class II and HCNE
statistically singnificant
Aesculin can causes
dilation of pupils, diarrhea, vomiting, paralysis
Chestnut side effects?
i. Concomitant use of herbs that have constituents that might affect platelet aggregation could theoretically increase the risk of bleeding in some people