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7 Cards in this Set
- Front
- Back
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What HBV markers are present during early infection?
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HBsAG, HBeAg, and IgM anti-HBc
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What HBV markers are present in chronic infection?
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anti-HBcAb, HBsAg, and Anti-HBcAb IgM during exacerbations
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What is the natural course of HBsAg and anti-HBsAb in a hepatitis B infection?
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HBsAg becomes detectable in serum 1-10 weeks after innoculation, and before symptoms or LFT abnormalities. It remains elevated for 4-6 months if the infection clears. anti-HBsAb appears weeks to months after HBcAg resolves.
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What does a positive anti-HBsAb and anti-HBcAb indicate? What does just a positive anti-HBsAb indicate
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anti-HBsAb and anti-HBcAb indicated immunity from natural infection, anti-HBsAb alone indicates vaccination.
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When is IgG anti-HBcAb detected?
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after conversion from IgM anti-HBcAb, after the resolution of acute hepatitis or conversion to chronic hepatitis.
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Can HBcAg be detected in serum?
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No, it is intracellular
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What serologic features help distinguish acute from chronic hepatitis B infection?
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Persistent HBsAg and Presence of HBV DNA
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