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9 Cards in this Set
- Front
- Back
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class
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anticoagulant
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action
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rapid onset anticoagulant. it exerts direct effect on blood coagulation by enhancing the inhibitory actions of antithrombin 3 therby blocking the conversion of prothrombin to thrombin and fibrinogen to fibrin.
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indications
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adjuvant therapy, to prevent thrombus fromation in AMI
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contraindications
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hypersensitivity, active bleeding, bleeding disorders, recent intrcranial, intraspinal, or eye surgery, htn, gi bleeding
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dose
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stemi: bolus 60 units/kg max of 4000 units continue with 12units/kg per hr and round to nearest 50 units max of 1000 an hr
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interaction
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aspirin and other nsaid increase risk of bleeding. nitro iv may decrease anticoagulant activity. protamine antagonizes effect of hepatin
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side effects
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numbness, headache, bleeding, htn, vasospasm, chest pain, brochospasm, itching, burning, urticaria
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precautions
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use caution in pt with alcoholism, hx of atopy, during menstration, 3rd tri of pregnancy or during or post partum. cerebral embolism.
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route
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iv
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