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19 Cards in this Set

  • Front
  • Back
What is circulatory shock?
Cardiovascular dysfunction associated with inadequate tissue perfusion of the vital organs, leading to collapse of homeostasis. CO is insufficient to meet peripheral metabolic needs.
What are the 5 causes of circulatory shock?
Hypovolemic
Septic
Neurogenic
Anaphylactic
Cardiogenic
What are the effects of blood loss on MAP? At what point does it become decompensated?
Initially, hemorrhage results in decrease in MAP that is compensated. Blood pressure is returned to normal within a few hours. At around 40% blood loss, the compensatory mechanisms fail.
What is the initial response to hemorrhage?
Decreased venous pressure, decreased EDV, decreased SV, decreased CO, decreased arterial pressure.
What are the stages of shock?
Compensated shock
Progressive shock
Irreversible shock
What is the baroreflex response in compensated shock?
Increased heart rate, cardiac contractility, arteriolar constriction and venous tone return CO toward normal.
What is the sympathetic response in compensated shock?
Decreased perfusion to nonessential organs.
What is the hormonal compensation in compensated shock?
Adrenal catecholamine release
RAAS activation to conserve water
ADH release to conserve water
Reduced ANP and BNP
How do the capillaries function in compensated shock?
Capillary hypotension due to arteriolar constriction causes absorption of fluid.
What is the result of increased absorption in the capillaries?
Decreased plasma colloid osmotic pressure to the dilution of plasma proteins.
What happens in decompensated shock?
Cardiac depression
Decreased vasoconstriction
Endothelial dysfunction
Acidosis
DIC
CNS depression
Reduced organ perfusion
What causes irreversible shock?
Loss of energy reserves required to maintain cellular function.
What are results of irreversible shock?
Increased capillary permeability
Multiple organ failure
Acute respiratory distress syndrome
Nitic oxide overproduction
Decreases in blood pressure
What are features of septic shock?
Fever, vasodilation, initial hyperdynamic phase followed by hypodynamic stage.
Cardiovascular failure, DIC, ARDS, multiple organ failure
What can potentially cause septic shock?
Peritonitis from uterus
Perforation of the gut
Generalized infection
Kidney or UTI
Trauma/ burn
What is SIRS? What are the criteria?
Systemic response to infection.
Temp >100.5 or <96.8
HR > 120bpm
RR>20breaths/min
Leukocytes >12000
What is the most important treatment in shock? Why must it be watched closely?
Fluids- increasing blood volume too much can cause edema and congestion due to overloading.
How is ventricular filling pressure measured?
Pulmonary capillary wedge pressure
Why are vasoconstrictors used to treat circulatory shock? Why are vasodilators?
Vasoconstrictors increase blood pressure, but can reduce tissue perfusion.
Vasodilators (dopamin, alpha 1 antagonist, beta agonist) are administered to relieve excess sympathetic constriction after cardiac output is elevated by fluids.