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64 Cards in this Set
- Front
- Back
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What is the Hemopoietic system responsible for?
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producing blood and blood products
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What does the hemopoietic system consist of?
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Blood- plasma, blood cells
Lymphatic system Bone Marrow Spleen |
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Plasma makes of what % of the total blood volume?
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55%
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3 types of blood cells:
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Erythrocytes
Leukocytes thrombocytes |
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Where are immune globulins synthesized by?
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Lymphatic system
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What are globulins responsible for?
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Fighting infectious agents
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What do Albumins regulate?
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the passage of water and solutes through capillaries
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Where are Albumins synthesized?
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in the liver
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Fibrinogen synthesized where:
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liver
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Where are erthrocytes formed?
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red bone marrow
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Erythrocytes are what shape?
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Biconcave with non nuleate
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What are erythrocytes responsible for?
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transporting oxygen and remove carbon dioxide
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what is life span of erythrocytes?
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120 days
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Where are erythrocytes phagocytosed/broken down?
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liver, spleen, bone marrow
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The iron is______
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reused
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The bilirubin is disposed where?
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gallbladder
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Erythrocytes carry what?
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antigen determining blood type
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AB+
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universal recipient
can receive blood from anyone |
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0-
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universal donor
can donate to anybody |
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Incompatible transfusion will result in:
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agglutination
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What is agglutination?
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body attacks new blood cells, clumps together forms a thrombus
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The 2 different types of white blood cells/leukocytes?
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Granular
non granular |
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What are white blood cells responsible for?
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Defense system
attack and phagocytosis |
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Where are granular cells formed?
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red bone marrow
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Life span of granular cells?
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2 weeks
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What does the Basophils granular cell do?
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release histamines, allergic reactions, hives, itching,watery eyes
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Neutrophil granular cells do what:
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leave capillary netowrk to attack infection in tissue (55-75%)
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Eosinophils
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for parasites primarily, or allergy
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Non granular white blood cells have a life span of:
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years
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Nongranular- no granules in cytoplasm and regular nuclei? T/F
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T
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Nongranular cells are formed where?
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lymphatic tissue or spleen
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Lymphocytes do what:
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responsible for making antibodies. Are rabidly dividing and radiosensitive
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What is skeletal imaging useful for in hemopoietic disorders?
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multiple myeloma and some leukemia
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What is chest imaging useful for in hemopoietic disorders?
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lymphatic changes in mediastium
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CT can evaluate:
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lymph node
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MRI useful in imaging:
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bone marrow
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Anemia:
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decreased hemoglobin in peripheral blood: decreased oxygen to peripheral tissues
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what is hemoglobin
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complex protein-iron compound
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Decrease of hemoglobin is caused by:
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increased rate of red cell destruction
loss of red blood cells(bleeding) |
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Iron deficiency Anemia may result from:
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chronic blood loss, malignant tumor, excessive bleeding, not enough iron, parasited
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Hemolytic Anemia
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shortened life span of red blood celss, hemolysis and release of hemoglobin into plasma
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Hemolytic anemia may result from:
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hereditary, allergic reaction, malarial parasite
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Common types of hemolytic anemia:
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spherocytic
sickle cell erythroblastosis fetalis thalassemia |
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Spherocytic anemia:
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erythocytes have round shape, not biconcave, fragile, susceptible to rupture. Oxygen efficient tissue
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What is treatment for spherocytic anemia:
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blood transfusion, pain management
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T/F all of the different types of anemia are hereditary?
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TRUE
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Sickle cell anemia:
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cells get stuck in capillaries. hemoglobin molecule is abnormal and cell is sickle shpaed when deoxygenated
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sickle cell anemia was originally developed to do what?
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protect those from malaria
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Whats most affected with sickle cell?
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extremities
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On an x-ray with sickle cell anemia what kind of shape are the vertebrae
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fish shaped. Concave on superior and convex inferior
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Erythroblastosis fetalis:
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mother RH negative
fetus RH positive |
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What happen with erythroblastosis fetalis:
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mother builds antibodies to Rh factor.
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Thalassemia is:
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due to defect in hemoglobin formation
rapid destruction of new blood cells |
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What happens to the medullary canal with thalassemis?
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it widens, thinning cortices
marrow may perforate- new bone spicules form under periosteum. Osteoblasts from under periosteum. |
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The majority of blood volume is composed of?
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plasma
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Bilirubin if formed during destruction of:
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erythrocytes
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which type of blood is considered to be the universal donor:
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o
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which cells are most important in the development of immunity?
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lymphocytes
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The most common pulmonary complication resulting from AIDS is:
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pneumocystis carinii pneumonia
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Kaposis sarcoma is frequently associated with AIDS and it my affect the:
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gastrointestinal system, lymph nodes, skin
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a neoplastic disease of the plasma is:
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multiple myeloma
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which type of leukemia predominantly affects children?
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acute lymphocytic
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Hemophilia:
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anomaly of blood coagulation,
spontaneous hemorrhage or sever bleeding |
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Is hemophilia more in males or females?
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males. women can be carriers
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