Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
7 Cards in this Set
- Front
- Back
|
What is the condition associated with the following peripheral blood smear findings:
1. cigar-shaped/pencil-thin red cells 2. small target cells/teardrop cells/basophilic stippling 3. coarse basophilic stippling 4. Rouleau formation 5. Spherocytes 6. Schistocytes 7. Bite cells 8. Teardrop cells/nucleated red cells/immature myeloid forms |
1. Fe deficiency anemia
2. thalassemia 3. sideroblastic anemia 4. monoclonal protein/cold agglutinin/increased fibrinogen 5. hereditary spherocytosis or immune hemolytic anemia 6. fragmentation hemolysis; micro- or macro-angiopathic hemolytic anemia (DIC, TTP, mechanical valve) 7. oxidative hemolysis 8. leukoerythroblastic anemia |
|
|
DDx for microcytic anemia? Need 4.
|
1. Fe deficiency
2. alpha thalassemia 3. beta thalassemia 4. sickle thalassemia |
|
|
DDx for megaloblastic anemia? Need 4.
|
1. Folate deficiency
2. Vit B12 deficiency 3. Drug induced (use history) 4. Erythroleukemia |
|
|
DDx for normocytic anemia? Need 7.
|
1. Acute blood loss
2. CKD 3. pure red cell aplasia 4. malignancy 5. alcoholic liver disease 6. anemia of chronic disease 7. hemolytic anemia |
|
|
DDx for hemolytic anemia? Need 7.
|
1. membrane defect
2. enzymopathies 3. hemoglobinopathies 4. AIHA (warm or cold) 5. Fragmentation disorders: DIC, TTP, HUS) 6. Infections: malaria, babesiosis 7. hypersplenism |
|
|
What are the 2 diagnostic features of aplastic anemia?
|
1. pancytopenia
2. hypocellular bone marrow |
|
|
What are the homocysteine and methlymalonic acid levels in Vit B12 and Folate deficiency?
|
1. B12: high homocysteine and methlymalonate
2. Folate: high homocysteine ONLY |
