Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

image

Play button

image

Play button

image

Progress

1/53

Click to flip

53 Cards in this Set

  • Front
  • Back
neoplasms associated with Down syndrome?
ALL, AML
neoplasms associated with tuberous sclerosis?
astrocytoma and cardiac rhabdomyoma
neoplasm associated with Plummer-Vinson syndrome (atrophic glossitis, esophageal webs, anemia; all due to iron deficiency)
squamous cell carcinoma of the esophagus
neoplasms associated with Paget's disease fo bone
secondary osteosarcoma and fibrosarcoma
neoplasm associated with immunodeficiency states
malignant lymphoma
neoplasms associated with AIDS
aggressive malignant lymphomas (non-Hodgkin's) & Kaposi's sarcoma
neoplasms associated with acanthosis nigricans
visceral malignancy (stomach, lung, breast, uterus)
abl
CML (oncogene)
c-myc
Burkitt's lymphoma (oncogene)
bcl-2
follicular and undifferentiated lymphomas (inhibits apoptosis) (oncogene)
erb-B2
breast, ovarian, and gastric carcinomas (oncogene)
ras
colon carcinoma (oncogene)
L-myc
Lung tumor (oncogene)
N-myc
neuroblastoma (oncogene)
ret
MEN II & III (oncogene)
Rb
13q; retinoblastoma, osteosarcoma (tumor suppressor)
BRCA1 and 2
17q, 13q; breast and ovarian cancer (tumor suppressor)
p53
17p; most human cancers, Li-Fraumeni syndrome (tumor suppressor)
p16
9p; melanoma (tumor suppressor)
APC
5q; colorectal cancer (tumor suppressor)
WT1
11q; Wilms' tumor (tumor suppressor)
NF1
17q; Neurofibromatosis type I (tumor suppressor)
NF2
22q; Neurofibromatosis type II (tumor suppressor)
DPC
18q; pancreatic cancer (tumor suppressor)
DCC
18q; colon cancer (tumor suppressor)
PSA
prostatic carcinoma
CEA
carcinoembryonic antigen; very nonspecific but produced by about 70% of colorectal and pancreatic cancers; also produced by gastric and breast carcinomas
alpha-fetoprotein
hepatocellular carcinomas; nonseminomatous germ cell tumors of the testes (e.g. yolk sac tumor)
beta-HCG
Hyatidiform mole, Choriocarcinomas, and Gestational trophoblastic tumors
CA-125
ovarian, malignant epithelial tumors
S-100
melanoma, neural tumors, astrocytomas
alkaline phosphatase
metastases to bone, obstructive biliary disease, Paget's disease of bone
bombesin
neuroblastoma, lung and gastric cancer
TRAP
tartrate-resistant acid phosphatase; hairy cell leukemia, a B cell neoplasm
HTLV-1
adult T cell leukemia
HBV, HCV
hepatocellular carcinoma
EBV
Burkitt's lymphoma, nasopharyngeal carcinoma
HPV
cervical carcinoma (16, 18), penile/anal carcinoma
HHV-8
Kaposi's sarcoma, body cavity fluid B cell lymphoma
aflatoxins
liver (hepatocellular carcinoma)
vinyl chloride
liver (angiosarcoma)
CCL4
liver (centrilobular necrosis, fatty change)
nitrosamines
esophagus, stomach
asbestos
lung (mesothelioma and bronchogenic carcinoma)
arsenic
skin (squamous cell carcinoma)
naphthalene (analine) dyes
bladder (transitional cell carcinoma)
alkylating agents
blood (leukemia)
t(9;22)
CML (bcr-abl hybrid)
t(8;14)
Burkitt's lymphoma (c-myc activation)
t(14;18)
follicular lymphomas (bcl-2 activation)
t(15;17)
M3 type of AML - responsive to all-trans retinoic acid
t(11;22)
Ewing's sarcoma
t(11;14)
mantle cell lymphoma