Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

image

Play button

image

Play button

image

Progress

1/48

Click to flip

48 Cards in this Set

  • Front
  • Back
erythrocyte
gas exchange, biconcave; source of energy - glucose
survival time- 120 days
anisocytosis
varying sizes
poikilocytosis
varying shapes
reticulocyte
immature erythrocyte
basophil
mediates allergic reaction
densely basophilic granules containing heparin (anticoag), histamine (vasodilator), and other vasoactive anmines, and LTD4
basophilic stippling
thalasemias
anemia of chronic disease
iron def anemia
lead poisoning
mast cell
mediates allergic reaction
degran: histamine, heparin, eosinophilic chemotactic factors
can bind IgE to membrane
type I HS reactions
Cromolyn sodium
prevents mast cell degranulation
tx asthma
eosinophils
bilobed nucleus
defense against helminithic and protozoan infections (major basic protein)
highly phagocytic for antigen-antibody complexes
eosinophilia causes
neoplasm, asthma, allergic processes, collagen vascular disease, parasites, Churg-Strauss, AIN, Addisons, drugs
Neutrophil
acute inflammatory response
bilobed nucleus; granules contain hydrolytic enzymes, lysozyme, MPO, lactoferrin
hypersegmented polys
seen in vit B12/folate def
monocyte
frosted glass cytoplasm, differentiates into macrophages in tissues
macrophage
phagocytosis bacteria, cell debris, senescent RC, scavenges damaged cells and tissues
activated by gamma IFN
B lympho
humoral response; produce antibodies
matures in marrow, migrates to peripheral tissues (LN follicles, white pulp of spleen, unencap lymphoid tissue)
difft into plasma cell; has memory (VAX)
B cell surface markers
CD 19, 20, 21, IgD, IgM
Plasma cell
abundant RER, well devloped golgi
produce antibody to a specific antigen
plasma cell neoplasm
multiple myeloma
russell bodies
accumulation of Ig in plasma cells in multiple myeloma
T lymph0
mediates cellular immune response; originate from stem cells in the bone marrow but matures in the thymus
cytotoxic T
MHC 1
CD 8
helper T
MHC II
CD 4
dendritic cells
professional APCs; express MHC II and FcR on surface
main inducers of primary AB response
intrinsic pathway
collagen, BM, activated platelets-->XII, XI, IX, X (meets extrinsic), thrombin, fibrin, clot
factor VIII
makes IXa to X
def of VIII
hemophilia A
def of IX
hemophilia B
extrinsic
tissue factor VII,X, thrombin, fibrin, clot
protein C and S
inactivate Va and VIIIa, vit K dependent
Antithrombin III
inactivates thrombin, IXa, Xa, and XIa
inactivated by heparin
vW factor
platelet aggregation to exposed collagen
platelet produces Ca for
XIa to IX
IXa to X
VII to VIIa
Xa to prothrombin (via Va)
citrate and Ca
citrate binds to Ca decreasing clotting
tpa
generates plasmin, which cleaves fibrin
factor V leiden mutation
resistance to activated protein C
bradykinin
increases vasodilation, increases permeability, increases pain
A blood group
A antigen on RBC surface, B antibody in plasma
B blood group
B antigen on RBC surface, A antibody in plasma
AB
universal recipient
O
neither A nor B antigen; both antibodies in plasma- universal donor
Rh+
transfusion into Rh- person can result in massive IgG production
macroovalocyte
megaloblastic anemia (also see hypersegemented PMNs), marrow failure
helmet cell, schistocyte
DIC, traumatic hemolysis
teardrop ccell
myeloid metaplasia with myelofibrosis
Target cell
Thalassemia, HbC disease, asplenia, liver disease
Poikilocytes
nonuniform shapes in TTP/HUS, microvascular damage, DIC
Burr cell
TTP/HUS
psammoma bodies
papillary adenocarc of thyroid
serous papillary cystadenoma of ovary
meningioma
malignant mesothelioma
(laminated concentric calc spherules)