Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
71 Cards in this Set
- Front
- Back
oval macrocyte
|
megaloblastic anemia
|
|
cabot ring
|
megaloblastic anemia
|
|
decreased folate or B12
|
megaloblastic anemia
|
|
1 six lobed PMH
|
Megaloblastic anemia
|
|
hypersegmented PMNs
|
megaloblastic anemia
|
|
Cabot ring
|
megaloblastic anemia
|
|
ineffective erythropoiesis
|
megaloblastic anemia
|
|
giant pronormoblasts
|
megaloblastic anemia
|
|
mean copuscular volume up
|
megaloblastic anemia,
B12 deficiency |
|
decreased folate or B12
|
megaloblastic anemia
|
|
alcoholism
|
folate deficiency and megaloblastic anemia
|
|
glossitis/stomatitis
|
folate deficiency
megaloblastic anemia |
|
poor myelination
|
cobalamin/B12 deficiency
|
|
1 six lobed PMH
|
Megaloblastic anemia
|
|
hypersegmented PMNs
|
megaloblastic anemia
|
|
Cabot ring
|
megaloblastic anemia
|
|
ineffective erythropoiesis
|
megaloblastic anemia
|
|
giant pronormoblasts
|
megaloblastic anemia
|
|
mean copuscular volume up
|
megaloblastic anemia
|
|
decreased folate or B12
|
megaloblastic anemia
|
|
alcoholism
|
folate deficiency and megaloblastic anemia
|
|
poor myelination
|
cobalamin/B12 deficiency
|
|
increased methyl melonic acid
|
B12 deficiency
|
|
increased homocysteine
|
B12 or folate deficiency
|
|
vegans or sever anorexics
|
B12 deficiency
|
|
gastric failure
|
B12 deficiency
|
|
Crohn's disease
|
B12 deficiency
|
|
Tropical sprue
|
B12 deficiency
|
|
bacterial overgrowth
|
B12 deficiency
|
|
Diphyllobothrium latum
|
(gefilte fish)
B12 deficiency |
|
achyloryhydria
|
pernicious anemia
|
|
groups with increased incidence of pernicious anemia
|
american blacks, northern europeans
|
|
dementia and psychological disturbances
|
B12 deficiency
|
|
demyelinating disease
|
B12 deficiency
|
|
increased serum Fe
increased Fe saturation negative for hemochromatosis |
megaloblastic anemia incuding iron metabolism abnormality
because of achlorhydira (and acid environment is needed for iron absorption) |
|
Schilling Test
|
B12 deficiency
(give B12 without IF, with IF and after AB) |
|
increased indirect bilirubin
|
hemolytic anemia
|
|
increased LDH
|
megaloblastic anemia (because LDH is dependent on RBCs and with decreased RBCs LDH just spills out)
hemolytic anemia (because of high level of broken RBCs) |
|
spectrin mutation
|
hereditary spherocytosis
|
|
increased osmotic fragility
|
hereditary spherocytosis
|
|
loss of central pallor
|
spherocytosis
|
|
lack of Decay Activating Factor
|
PNH
|
|
cell lysis at higher salt concentrations
|
osmotic fragility of hereditary spherocytosis
|
|
CD-59
|
DAF in PNH
|
|
CD55
|
PNH
|
|
HAM test
|
PNH
|
|
Reddish black urine in morning
|
PNH
|
|
GPI bridge
|
PNH
|
|
PIG A gene
|
PNH
codes for the GPI bridge |
|
aplastic anemia
primary marrow problems thrombi |
sequelae of PNH
|
|
G6PD deficiency
|
hemolytic anemia
|
|
pyruvate kinase deficiency
|
hemolytic anemia
|
|
heinz bodies
|
G6PD deficiency - hemolytic anemia
|
|
quinine
|
exacerbates G6PD deficiency hemolytic anemia
|
|
fava beans
|
exacerbates G6PD deficiency hemolytic anemia
|
|
quick decay of RBCs
|
G6Pd deficiency
|
|
Bite cell
|
hemolytic anemia
|
|
Schistocytes
|
mechanical hemolytic anemia
|
|
Direct Coombs test
|
immune hemolytic anemia
measures presence of immunoglobulin or complement |
|
Indirect Coombs
|
immune hemolytic anemia
looking for antiRBC antibodies in serum |
|
Quinidine
Quinine isoniazid |
immune complex mechanism of Drug-related hemolytic anemia
|
|
penicillin
chephalosporin |
haptenic mechanism of Drug-related hemolytic anemia
|
|
methyldopa
ldopa procainamide ibuprofen |
true autoimmnue mechanism of Drug-related hemolytic anemia
|
|
immediate intravascular hemolysis
|
Alloimmune hemolysis doe to preformed antibodies and resulting hemolytic transfusion reaction
|
|
slow extravascular hemolysis
|
Alloimmune hemolyis due to repeat exposure to a foreign antigen leading to hemolytic transfusion reaction
|
|
Rh incompatibility
|
alloimmune hemolysis
|
|
igG
|
Warm type autoimmune hemolysis
|
|
hemolysis that responds to steroids
|
warm type autoimmune hemolysis
|
|
IgM
|
cold type autoimmune hemolysis
|
|
hemolysis that responds to plasmaphoresis
|
cold type autoimmune hemolysis
|
|
hemolysis that responds to splenectomy
|
warm type autoimmune hemolysis
|