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29 Cards in this Set
- Front
- Back
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what enzymes are inhibited by lead poisoning
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ferrochelatase
ALA Hehydratase |
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antibiotic that:
inhibits peptidyltransferase |
chloremphenical
streptogramin |
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antibiotic that:
blocks translocation |
macrolides
linezolid |
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antibiotic that:
prevents attachment of tRNA |
tetracyclines
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antibiotic that:
inhibits RNA polymerase |
rifampin
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antibiotic that:
inhibits topoisomerase |
fluoroquinilones
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antibiotic that:
inhibits DHF reductase |
TMP
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test used to diagnose thalassemia
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hemoglobin electrophoresis
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microcytic anemia with difficulty swallowing and glossitis
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plummer vincent
-iron def |
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microcytic anemia with greater than 3.5 HbA2
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B minor
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megaloblastic anemia not correctable with B12 or Folate
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orotic aciduria
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megaloblastic anemia with peripheral neuropathy
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B12 def
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microcytic anemia with basophilic stippling
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lead poisoning
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microcytic anemia thats reversible with B12
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sideroblastic anemia
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macrocytic anemia in HIV patient
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zidovudine
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normocytic anemia and red urine in the morning
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PNA
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normocytic anemia with elevated creatinine
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kidney failure
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what can cause aplastic anemia
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Virus
drugs fanconis |
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what is the defect in B thalassemia
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point mutation in splicing and promoter site
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what type of cells are seen in B thalassemia
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target
anistocytes |
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what population is B thalassemia common
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mediterranean
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what population is a thalassemia common
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asian
african |
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Hb seen in 4 deletion in a thalassemia
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Hb Barts (y4)
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Hb seen in 3 deletion in a thalassemia
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HbH (B4)
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what causes basophilic stippling
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inhibition of rRNA degradation
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where are ringed sideroblasts found
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BM
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when would you see a crew cut appearance in X ray
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B thalassemia
Sickle cell |
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how can you differentiate B12 and folate def
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B12 has neurological symptoms as well as increased methylmalonic acid
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cells seen in lead poisoning
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ringed sideroblasts
basophilic stippling |
