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24 Cards in this Set
- Front
- Back
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>25% blasts |
Leukemia |
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<25% blasts with non tender LN |
Lymphoma |
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ALL |
4.11 B cell issue High wbc with lymphocyte predominance Fever organomegaly joint pain Can also present with low WBC and pancytopenia Rx Chemo , if relapse : BMT |
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AML |
Similar sx like ALL High WBC RBC and PLT may be low due to marrow infiltration Auer Rods |
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Hodgkins |
Good prognosis Teenage patient with non tender cervical or supraclavicular LN Later : fevers , night sweats , Weight loss, generalized lymphadenopathy Normal to high WBC High or low lymphocytes Diagnosis: excisional node biopsy , reed sternberg cels : B cell origin If negative ppd choose Hodgkins If 5-10 choose atypical mtb >15 choose MTB |
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NHL |
Bad prognosis Rapidly growing non tender mass in head neck or abdomen |
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Long bond tumor malignancies |
Osteogenic sarcoma Ewing’s UNilateral worsening pain Often post traumatic Growing pains bilateral |
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Ewing’s |
Onion peel Sunburst pattern Very painful Pelvis Mc |
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Osteochondroma |
Cartilaginous cap Benign tumor near growth plate |
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Osteoid osteoma |
Benign worse at night Relieve by ASA Central radiolucency with thickened bone around it |
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Mc abdominal tumor in kids |
Wilms aka nephroblastoma Asymptomatic unilateral flank mass WAGR All hemihypertrophy increased risk of wilms and hepatoblastoma HH sx : BWS , kliepper trenaunay , Russel Silver , Proteus |
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Retinoblastoma |
Leukocoria Increased risk of osteosarcoma High rate of spontaneous mutation Chromosome 13 + eye problem or long bone X-ray: consider dx |
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Neuroblastoma |
Most common extracranial solid tumor Usually presents in abdomen less than 5y M>F Purple Hue to eyelids and ecchymoses in periorbital area From lymphoid tissue involvement Dancing eyes , myoclonus Prognosis good if less than a year old Elevated urine VMA |
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Craniopharyngioma |
Pituitary calcification |
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Posterior fossa tumor MC, MC after 2y |
Medulloblastoma |
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LCH or Histiocytosis X |
Papular rash associated with Petechiae in Inguinal folds, suprapubic fold and perianal area Lytic bone lesion in skull Diabetes insupidis Rx remove lesion , steroids chemo |
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Rhabdomyosarcoma |
Mc soft tissue sarcoma in kids Worsening post traumatic pain Recital mass Grape like vaginal mass |
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Tumor lysis sx |
High K , high phosphorus, high Uric acid level Rx allopurinol , aggressive hydration |
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Anterior mediastinal mass |
High risk of respiratory failure or SVC syndrome Mass may be lymphoma, ectopic thyroid tissue or thymoma |
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SVC syndrome |
Facial swelling Dusky color due to venostasis Weight loss , night sweats due to presence of malignancy Usually due to lymphatous mass |
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TAR syndrome |
TOF association Low megaK |
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Lead poisoning |
Elevated zinc and erythrocyte protoporphyrin levels |
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Chemo AE |
Cardiomyopathy can occur from doxorubicin even 10 years or more after treatment; etoposide may lead to secondary leukemia within 3 years of exposure; and breast cancer is increased in survivors of Hodgkin lymphoma. |
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Kasabach-Merritt |
hemangioma thrombocytopenia syndrome). |
