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16 Cards in this Set
- Front
- Back
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Fanconi's anemia syptoms
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1) anemia
2) hypoplasia of kidney 3) absent or hypoplastic thumbs or radii |
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Malignant Mesothelioma IHC pattern
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WT-1 +
calretinin + CK 5/6 + Neg for CD15, B72.3, CEA, BerEP4 |
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SCC in lung IHC pattern
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CK 5/6 +
p63 + calretinin - WT-1 - |
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normal plasma cell IHC profile
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CD138 +
CD38 bright CD19 + CD56 - |
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Abnormal MM plasma cell IHC profile
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weaker expression of CD38
CD138+ CD19 - CD56 +/- |
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MM according to FISH results, pts are stratified into 3 groups
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1) shortest survival t(4,14), t(14,16), or 17 del
2) intermediate 13q del 3) good t(11,14) |
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Plasma leukemia has higher incidence of ___ paraprotein
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IgE
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T-ALL, which markers are used the most specific precursor nature of T lymphoblast
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TdT
CD99 CD34 CD1a |
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T-ALL, what marker is considered lineage specific
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CD3
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T-ALL -> CD4, CD8 ??
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CD4 and CD8 often coexpressed
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Characteristic marker for NK cell
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CD56
CD 16 (NK cells and granulocytes) |
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Feature of pro T/pre T
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CD4-
CD8 - |
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Feature of cortical T
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CD4 +
CD8 + |
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Feature of medullary T
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Either CD4/CD8 pos
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Pediatric follicular lymphoma 2 features
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no BCL protein
no t(14,18) Grade 3 |
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DLBCL common genotype
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30% rearrangement of BCL6
10% t(14,18) (BCL2 gene) |
