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11 Cards in this Set
- Front
- Back
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single most accurate test for Fe defi.
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BM
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Only An. w/ Hi circulating Fe.
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sideroblastic An
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Tx for Fe defi.
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Give/replace Fe honey :)
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EPO is given only in-
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End stage renal Ds , not in routine.
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Least efficient way for replace Fe-
Most effective way- |
FeSo4=33% Fe, (98% goes in stool,other are Fe-gluconate=30%, Fe-fumarate)
Blood transfusion most efficient way to replace(not MCC :) |
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Blood transfusion
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by IM or IV
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Single Most accurate test for sideroblastic An.
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Fe build up in (ringed sideroblasts )mitochondria- stain is prussian blue stain
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Tx for Sd An
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Knock off the toxin-
small no can be treated by Pyrodoxin, as Sd An is sec. to use of Alcohol and prevent absorption and icorporation of Fe in the normal Hg. (in rare cases)Hereditary defi. of Delta-9 Alpha Levulinic Acid synthetase are tx with pyridoxine. |
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Thalsemia
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An w/ normal Fe studies.
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Dx of type of thalasseamia-
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By Electrophoresis-
Alpha- missing a- chains beta-missing b-chains A=2a+2B chains A2=2a+2delta F=2a+2Gamma |
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Sx in relation to no. of deleted/defective genes of Hg.
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1 gene= asyptomatic,normal
2 gene defect=mild Alpha thal 3=Moderate alpha thalsemia 4= Die in utero 4-5 mnth |
