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13 Cards in this Set
- Front
- Back
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hallmark: REED-STERNBERG CELL; huge cell, found in BM, tissue, and lymph nodes; too big to be found in circulation; diagnostic for this disease; lymph node based disease; poorer prognosis if nodes involved are on both sides of the diaphragm; prognosis is better if nodes are only on one side
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Hodgkkin's Disease (HD) type of lymphoma
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2 stages of Hodgkins disease
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1) A - without general symptoms
2) B - with general symptoms that include weight loss, fever, night sweats |
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malignancy that spreads via the blood throughout the entire lymphoid/hematopoietic system
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leukemia
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malignancy of the lymphoid system witch has a circumscribed, solid tumor
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lymphoma
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a group of diseases that aris from cells of the lymphoid tissues - lymphs, histeocytes, and reticulum cells
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lymphomas
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2 types of lymphomas
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1) hodgkin's
2) non hodgkins |
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thre regions of the genetic code that regulate growth and reproduction of the immune system are damaged; they think that EBV and others cause harm when they cause persistent antigenic stimulation; often associated with numeric and/or structural abnormalities in chromosomes
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non hodgkin's lymphoma
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malignant popularion of lymphs arrested at a particular stage of lymph maturation
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malignant lymphomas
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2 types of non hodgkins lymphomas
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1) Burkitts
2) Burkitt-like or undifferentiated, non burkitt lymphoma |
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*endemic to africa
* most often strikes the facial bones, especially the jaw * is an aggressive disease and is rapidly fatal if untreated, however, it is curable |
Burkitt's
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*seen mostly in adults
*usually fatal |
burkitt like
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B cell subset; lymphoproliferative disorder; will see mononuclear lymphs that have unusual cytoplasmic projections that are hair-like; will cause DRY TAP; TRAP STAIN IS POSITIVE
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Hairy Cell Leukemia
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many T lymphs are in the skin and they become cancerous and form hideous skin lesions; look like moon craters with black centers; also called mycosis fungoides and sezary's syndrome; most common cutaneous T cell lymphoma; HALLMARKED by abnormal circulating lymphocytes called Sezary cells (size of a small lymph with numerous folds and grooves in the nucleus (brain like) (baby butt)
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Primary Cutaneous T-cell Lymphoma
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