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22 Cards in this Set

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steps from pluripotent hematopoietic stem cell to neutrophil, eosinophil, basophil
-pluripotent hematopoietic stem cell

-myeloblast

-promyelocyte

-myelocyte

-metamyelocyte

-stab cell

-neutrophil, eosinophil, ,basophil
types of leukocytes (2 main groups, and subgroups)
granulocytes (basophils, eosinophils, neutrophils)

mononuclear cells (lymphocytes, monocytes)
# of leukocytes per microliter
4000-10,000 leukocytes per microliter
how many lobes do basophils have?
bilobate nucleus
basophils are what % of leukocytes?
<1% of all leukocytes
what drug prevents mast cell degranulation?
cromolyn sodium
eosinophils are what % of leukocytes?
1-6%
neutrophils are what % of WBCs?
40-75%
monocytes are what % of leukocytes?
2-10%
how many lobes do eosinophils have?
bilobate nucleus
what proteins do Eosinophils produce?
histaminase and arylsulfatase
5 causes of eosinophilia

(remember NAACP)
Neoplastic
Asthma
Allergic
Collagen vascular diseases
Parasites
Which is the "acute inflammatory response cell"
neutrophils
what type of WBCs do you see in Vitamin B12/folate deficiency?
Hypersegmented polys (neutrophils)
how many lobes do neutrophils have?
multilobed
what do monocytes look like?
large.
kidney-shaped nucleus
extensive "frosted glass" cytoplasm.
differentiates into macrophages in tissues
multiple myeloma is a neoplasm of what cells?
plasma cells
what does CD stand for?
Cluster of Differentiation
where are monocytes located? where are macrophages located?
monocytes are circulating in the blood. Monocytes differentiated into marcrophages in the tissues
what protein activates macrophages
gamma-interferon
what are dendritic cells of the skin
langerhans cells.
what are the main inducers of primary antibody response?
dendritic cells are the main inducers of primary antibody response