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22 Cards in this Set
- Front
- Back
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steps from pluripotent hematopoietic stem cell to neutrophil, eosinophil, basophil
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-pluripotent hematopoietic stem cell
-myeloblast -promyelocyte -myelocyte -metamyelocyte -stab cell -neutrophil, eosinophil, ,basophil |
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types of leukocytes (2 main groups, and subgroups)
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granulocytes (basophils, eosinophils, neutrophils)
mononuclear cells (lymphocytes, monocytes) |
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# of leukocytes per microliter
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4000-10,000 leukocytes per microliter
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how many lobes do basophils have?
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bilobate nucleus
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basophils are what % of leukocytes?
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<1% of all leukocytes
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what drug prevents mast cell degranulation?
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cromolyn sodium
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eosinophils are what % of leukocytes?
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1-6%
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neutrophils are what % of WBCs?
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40-75%
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monocytes are what % of leukocytes?
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2-10%
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how many lobes do eosinophils have?
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bilobate nucleus
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what proteins do Eosinophils produce?
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histaminase and arylsulfatase
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5 causes of eosinophilia
(remember NAACP) |
Neoplastic
Asthma Allergic Collagen vascular diseases Parasites |
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Which is the "acute inflammatory response cell"
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neutrophils
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what type of WBCs do you see in Vitamin B12/folate deficiency?
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Hypersegmented polys (neutrophils)
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how many lobes do neutrophils have?
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multilobed
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what do monocytes look like?
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large.
kidney-shaped nucleus extensive "frosted glass" cytoplasm. differentiates into macrophages in tissues |
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multiple myeloma is a neoplasm of what cells?
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plasma cells
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what does CD stand for?
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Cluster of Differentiation
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where are monocytes located? where are macrophages located?
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monocytes are circulating in the blood. Monocytes differentiated into marcrophages in the tissues
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what protein activates macrophages
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gamma-interferon
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what are dendritic cells of the skin
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langerhans cells.
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what are the main inducers of primary antibody response?
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dendritic cells are the main inducers of primary antibody response
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