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78 Cards in this Set

  • Front
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Anemia

A decrease in hemoglobin levels within the blood to values less than normal

Antibody

An immunoglobulin produced by lymphocytes in response to presence of bacteria, virus or any other antigenic substance

Antigen

A substance, usually protein, That stimulates the production of an antibody specific to that protein

Dyscrasia

Pertaining to an abnormal condition of blood or bone marrow

Endemic

Indigenous to a specific area

Methemoglobinemia

A blood disorder in which an abnormal amount of methemoglobin, a form of hemoglobin, is produced

Spherocytes

Abnormally round red blood cell containing more than normal amounts of hemoglobin

Thrombocytopenia

A decrease in the number of thrombocytes

Erythrocyte disorders are associate with

Decreased production


Increased destruction


Inappropriate loss of RBCs

Is anemia a primary condition or secondary condition

Secondary to a primary disorder elsewhere in the body

What can cause anemia

Hemorrhage


Hemolysis


Blood parasites


Iron deficiencies


Immune-mediated disease


Toxins

What is needed to diagnosis and determine if anemia is regenerative or nonregenerative

CBC


Blood films

What will be present in the blood film if anemia is regenerative

Reticularcytes

What are reticularcytes

Immature RBCs

What is the most common cause of anemia

Hemorrhage due to trauma

If internal hemorrhage is occur what diagnostic test my give false results

Hematocrit

What are the cs of thrombocytopenia that cause anemia

Petechial hemorrhages



How does iron deficiency affect the RBCs

The formation is altered and they have a decreased life span

In dogs, hemolysis is most commonly caused by the immune system components attaching to the RBCs membrane and

Alter its structure causing the body to remove the RBCs

In cats, hemolysis is most commonly caused by ________ that will attached to the RBCs membrane and alter its structure causing the body to remove the RBCs

Bacteria

What is hemobartonellosis

Bacteria attaching to RBCs membrane and altering them

How is hemolysis treated

Suppressing the immune system


Tetracycline/doxycycline (for hemobartonellosis)


Transfusion

What is isoerythrolysis

Neonates RBCs are lysed because the dam passes antibodies against the neonates RBCs in her colostrum

What blood parasite, that is common in cats, will cause anemia

Mycoplasma hemofelis

Blood parasites will cause __________ which leads to anemia

Hemolysis

What blood parasites,that is common in dogs, will cause hemolysis leading to anemia

Babesia canis


Babesia gibsoni

How are B. canis and gibsoni transmitted to dogs

Brown dog tick

Blood in urine will ______ when spend down

Fall to the blood

Hemoglobinuria will ________ when spend down

Stay suspended

What protozoal organism will cause a fatal form of anemia in cats

Cytauxzoon felis

What are Heinz bodies

Hemoblobin denatures forming aggregates of irreversible hemichromes

Exposure of erythrocytes to ________ can produce reversible and nonreversible hemichromes

Oxidants

How will Heinz bodies appear in feline RBCs samples

Large eccentric pale structures



How will Heinz bodies appear in canine RBCs samples

Multiple small structures

What is the most common cause of Heinz body in dogs

Onion toxicity

What is methemoglobinemia

Denatured hemoglobin

What are the cs of anemia

Pale mm


Lethargy


Exercise intolerance


Tachycardia


+/-murmur


Increased respiratory rate

Intravascular hemolysis will result in

Hemoglobinemia


Hemoglobinuria

Extravascular hemolysis will result in

Bilirubinemia


Bilirubinuria


Icterus

What is IMHA

Immune-mediated Hemolytic Anemia

What causes IMHA

Unknown

Who is predisposed to IMHA

2-8 year old dogs


Female


Poodles


Old English Sheepdogs


Irish Setters


Cocker Spaniels

What are the cs of M. hemofelis

Weight loss


Anorexia


Fever


Hepatomegaly


Splenomegaly



What are the cs of B. canis and gibsoni

Hemoglobinuria


Dehydration


Fever


Anorexia


Depression

What are the cs of IMHA

Anorexia


Listlessness


Weakness


Depression


Tachycardia


Tachypnea


+/- icterus


+/- hepatomegaly and splenomegaly


Necrosis of distal extremities


Pale mm



How is IMHA diagnosed

CBC


Agglutination test


Direct Coombs test


Direct immunofluorescence assay

What are band cells

Immature neutrophils

IMHA has a guarded prognosis and _________ is common

Relapse

What is IMTP

Immune-Mediated Thrombocytopenia

What occurs during IMTP

Platelets are coated with antibodies and the body destroys them

What causes IMTP

Unknown

How low does the platelet count have to be for bleeding problems to develop

>30,000 thrombocytes/ mmL

What are the cs of IMTP

Petechial hemorrhages


Ecchymotic hemorrhages


weakness


Lethargic

What are megakaryocytes

Cells that produce platelets

The prognosis for IMTP is guarded to good and _______ may occur

Relapse

What is Evans syndrome

Having IMTP and IMHA at the same time

What tick spreads Ehrlichiosis

The brown dog tick

Ehrlichiosis, the organism multiplies in what cells

Mononuclear cells


Fixed and circulating

Ehrlichiosis causes

Platelet consumption


Endothelial damage


Erythrocyte destruction


Suppression of bone marrow

What are the cs of acute Ehrlichiosis

Depression

Anorexia


Fever


Weight loss


Ocular and nasal discharge


Dyspnea


Edema


Lymphadenopathy


What are the cs of chronic ehrlichiosis

Bleeding tendencies


Severe weight loss


Debilitation


Abdominal tenderness


Anterior uveitis


Retinal hemorrhages

What is the most common inherited hemostasis disorder

Von Willebrand Disease (vWD)

vWD factor promotes what

Platelet clumping

Who is prone to vWD

Doberman


Pinschers


German Shepherds


Labrador Retriever

What are the three levels of vWD

Deficiency


High deficiency


No vWD

What are the cs of vWD

Easy bruising


Prolonged bleeding during estrus


Prolonged belled from venipuncture

How is vWD diagnosed

Buccal mucosal bleeding time >4 min

Most feline lymphomas are induced by

FeLV

How are feline lymphoma diagnosed

Mediastinal


Alimentary


Multicentric

Mediastinal lymphoma is the area

Bw the lungs

Alimentary lymphoma is the area

of the GI tract

What are the cs of mediastinal lymphoma

Dyspnea


Tachypnea


Regurgitation


Cough


Anorexia


Depression


Weight loss


Pleural effusion

What are the cs of alimentary lymphoma

Vomiting


Diarrhea


Weight loss


Intestinal obstruction

What is the most common form of lymphoma

Multicentric lymphoma

Is there a cure for lymphoma

No

What is the most common hematopoietic tumor in dogs

Lymphosarcoma

What are the cs of canine lymphoma

Enlarged peripheral lymph nodes


Lehtargy


weight loss


Vomiting


Diarrhea



How is predisposed to canine lymphoma

Boxers


Bullmastiffs


Basset Hounds


Saint Bernards


Scottish Terriers