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23 Cards in this Set
- Front
- Back
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Iron must be available for what?
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hemoglobin synthesis
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Is iron difficult to absorb?
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Yes it is very hard to absorb
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How much iron is absorbed through dietary sources?
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10%
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How much iron is absorbed through supplements?
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60%
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What is the best way to take iron supplements?
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-take w/ vitamin C
-better on empty stomach -do not take with coffee, tea, eggs, or whole grain breads -you want smaller amounts throughout the day vs. larger doses at one time |
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What is it called if someone has high levels of iron?
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hemochromatosis
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What are some of the bad SE of iron?
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-OD in children
-GI distress/ulcers (black stools) -teeth staining (liquid form) |
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What colon cancer screening tool gives false positive if taking iron?
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-hemoccult
-guiac tests |
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What is the antidote for excessive iron?
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deferoxamine (Desferal)
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What is erythropoietin?
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glycoprotein hormone that stimulates production of RBC in the bone marrow
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What makes erythropoietin?
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kidneys
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What is the process by which the body makes RBC, WBC & platelets?
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hematopoiesis
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In what type of pt do we use epogen?
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-CRF (chronic renal failure)
-HIV-infected -chemotherapy induced anemia (cancer cannot be in bone marrow) |
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What is the danger of too much epogen?
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-risk of MI, CVA & HF (increased viscosity)
-risk of blood clots -HTN |
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Why do athletes abuse epogen?
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increase oxygen carrying capacity
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How does filgrastim work?
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acts on cells in bone marrow to produce more neutrophils
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Who might we use filgrastim in?
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-chronic neutropenia
-cancer pt receiving chemotherapy (cancer cannot be in bone marrow) |
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What are (2) SE of filgrastim?
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-bone pain
-leukocytosis |
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How can filgrastim be administered?
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-IV
-subQ |
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How can filgrastim not be administered? Why?
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-PO; it is a protein and will be destroyed by GI tract
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What can we give to stimulate platelet production?
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oprelvekin (Interleukin-11)
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Who might we use oprelvekin (Interkeukin-11) in?
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-pt receiving chemotherapy
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What are the SE of oprelvekin (Interkeukin-11)?
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-fluid retention
-cardiac dysrhythmias -anaphylaxis |
