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33 Cards in this Set
- Front
- Back
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Germinal Center in Secondary follicle of LN * Contains B cells and macrophages |
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Medullary Cord/Sinus of LN * Contains B cells and Plasma cells |
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Lymph node A = subcapsular sinus B = germinal center w/ B cells C = mantle zone w/ naive B cells |
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Lymph Node Black arrow = subcapsular sinus White arrows = germ centers of secondary follicle Red circle = primary follicle |
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Tingible-body Macrophage in germinal center of LN *remove apoptosed B cells that fail selection |
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Paracortex of LN *Contains T cells |
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What are the black fibers? |
Reticular fibers (type 3 collagen) made by reticular cells in LN |
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Arrowhead = Follicular Dendritic cell in LN Arrow = Mantle |
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Infant Thymus (ie no fat) A - capsule B - Trabeculae (separate lobes) C - Cortex (darker) D - Medulla (lighter center) |
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Adult Thymus (fatty) A - Fat B - cortex C - Hassall's Corpuscle D - Medulla |
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Thymus Cortex A- Thymocytes (immature CD4- and CD8-) B - Macrophage C - epithelial reticular cell |
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Thymus Medulla Upper - Mature (CD4+ or CD8+) T cell Mid - Epithelial Reticular cell Lower - Hassall's Corpuscle |
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Hassall's Corpuscle - concentric arrangement of epi. reticular cells and keratin. Found in thymus medulla |
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Spleen Black - Capsule Red - White Pulp (lymphoid aggregate) Green - Red Pulp (cords) Blue and Orange - Sinuse Orange |
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Spleen A - Central artery B - Periarterial Lymphatic Sheath (PALS) - contain T-cell C -Sinus |
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Spleen - white pulp 1 - Germ. center 2 - mantle 3 - Marginal zone 4 - PALS 5 - aterioles 6 - Red pulp 7 - trabeculae |
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Spleen - red pulp A - Endothelial cell B -Macrophages C - SInus |
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Peyer's Patch *GALT in ileum Arrow = germinal center |
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Tonsil (oral MALT) Upper arrow = crypt Lower arrow = epthelium |
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Sample taken from tonsils |
Benign Tonsilitis from an Acute Infection
A - Inflammatory Cells in epithelium B - Hyperplasia of lymphoid tissue |
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Sample taken from lymph node |
Chronic Lymphadenitis w/ Follicular Hyperplasia
*Increase in # of follicles and variety in size *Seen in RA and early HIV
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Taken from a mass in a lymph node |
Necrotizing Caseous Granuloma
A - Lymphocytes B - Histeocytes (macrophages and epitheloid cells) C - Caseous (necrotic) material |
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Taken from a mass in a lymph node |
Langhans-type giant cell in a Necrotizing caseous granuloma |
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Taken from a mass in a lymph node |
Epitheloid Cells (activated macrophages) in a caseous granuloma *Have elongated nuclei and lots of pink cytoplasm |
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Taken from a mass in a lymph node |
Non-necrotizing caseous granuloma
*unlike necrotizing type, these granulomas have cells in center (not amorphous substance) |
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Taken from a mass in a lymph node |
Metastatic carcinoma in subcapsular sinus *abnormal glandular tissue in capusle |
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Taken from a mass in a lymph node |
Metastatic carcinoma in subcapsular sinus *abnormal glandular tissue in capusle |
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Taken from mass in anterior mediastinum |
Thymoma
*Tumor of epithelial cells of thymus, usually benign |
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Taken from mass in anterior mediastinum |
Thymoma
*Tumor of epithelial cells of thymus, usually benign |
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Cross section of a spleen. Spleen was measured to be 1,500 grams. |
Splenic Infarct and Splenomegaly (normal is 150g) |
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Cross section of a spleen |
Splenic infarct w/ coagulative necrosis |
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Spleen |
Perisplenitis - fibrous capsule that occurs after peritonitis or ascites |
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Spleen |
Lacerated spleen |
