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15 Cards in this Set
- Front
- Back
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Depression and cortisol
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People with depression have HIGH cortisol levels
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Depression and thyroid hormones
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1/3 or depressed people have blunted TSH. In these people treat the thyroid and if the symptoms go away it wasn't depression
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What are the primary NT's of depression?
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Low levels of serotonin and NE. NOTE: these NT's affect each other because where 5HT goes so will NE (bipolar being the exception)
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Primary NT's of bipolar?
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High NE and low serotonin (these normally follow each other, this is the exception)
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What is the incidence of sig. loss/stress before a major depressive episode? of anxiety with depression?
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90%
50% |
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Bipolar type II
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never has the very extreme manic episode of Type I, not grandiose, don't lose touch
When in hypomanic episode they will have a lot of energy and get a lot done, no psychotic features |
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What is the onset of bipolar disorder?
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Late teens, early 20's
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Manic episode
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Persistantly elevated, expansive or irritable mood for at least one week
Speak and think quickly, pressured speech ***MAIN PRIORITY after safety is hydration and nutrition b/c person can't pay attention long enough to eat and drink*** They will start but not finish a goal directed activity High risk activity, impulsive w/o insight Frequently follows a stressor, begins suddenly with rapid escalation |
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Major depressive episode in relation to manic episode?
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Majority will have a major depressive episode right before or after manic episode
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What type of bipolar episode is at highest risk for suicide or harm to others?
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Mixed episode
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What is the key to mood/affect in bipolar patient?
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LABILE
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Why do manic and depressed pts get constipated? have poor hygiene?
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Constipation: Body is slowed or the person is dehydrated, not paying attention to the body
Hygiene: depressed can't manage it, manic get too distracted |
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What percentage responds to ECT?
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85%, improve initially but not a long term cure, reset the brain for medicine to work
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What pt population is ECT less effective for?
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Older pts with dementia
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Who should not receive ECT?
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Cardiac pts (b/c ECT has a low incidence of cardiac effects)
Pt with brain tumor, neck injury |
