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38 Cards in this Set

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Definition of Chronic Renal Faliure
- when the kidneys are no longer capable of maintaining an internal environment consistent with life.
- Less than 15% GFR (stage 5)
- Damage to kidneys is irreversible
Is damage to the kidneys reversible after a person is diagnosed with chronic renal failure?
No.
What are the stages of chronic renal failure?
Stages 1-2 = impairment
Stages 3-4 = insufficiency
What is certain when a person is diagnosed with Chronic Renal Failure
Death
What stage of Chronic Renal Failure is a person in when their GFR is < 15%
Stage 5
Treatment Modalities for Chronic Renal Failure
- Conservative Management: diet and nutrition
- Renal Replacement Therapies: dialysis and transplantation
- Palliative care
What are the two forms of dialysis?
- hemodialysis
- peritoneal dialysis
What kind of dialysis do the young and old do better with?
Peritoneal dialysis
Common causes of Chronic Renal Failure
- Diabetic nephropathy
- Hypertensive nephropathy
- Glomerulonephritis
- Pyelonephritis
- Polycystic Kidney disease
70% of chronic renal failure cases are caused by what?
- Diabetes or hypertension
- It changes their microvasculature in the kidneys and it becomes ischemic which leads to necrosis
What is glomerulonephritis
- and antigen/antibody condition where the body attacks the kidneys
What is pyelonephritis
Inflammation related to infection within the kidneys
What is polycystic kidney disease
A genetic condition where plasma like fluid builds up in the kidneys
What happens to fluid balance in ESRD?
- Fluid volume won't be well regulated
- Nursing problem: Fluid volume excess. It is rare for fluid volume deficit to occur
What happens to electrolyte balance in ESRD?
- The body will retain electrolytes if they're low in the blood.
- The body will release them if they're high in the blood
- Especially concerned about Na and K
- Nursing problem with elevation in Na: alteration in mental status (seizures)
- Nursing problem with elevation in K: arrhythmias
Elevation in Na causes:
alterations in mental status (seizures)
Elevation in P causes:
Arrhythmias
What happens to acid/base balance in ESRD?
- Remember that the kidneys are the body's 3rd system to keep acid/base in balance
- Nursing problem with metabolic acidosis: decreased cellular activity (depression)
What happens to the excretion of metabolic wastes in ESRD?
- BUN and creatinine levels change
- Nursing problem: elevation in creatinie and BUN causes acidosis and azotemia
How is creatinine produced?
- a break down of the skeletal muscle system
- an increase affects every system in the body
How is BUN affected by ESRD?
- the increased protein in the diet and blood in the GI system causes these levels to rise
- an increase affects every system in the body
How is the excretion of medications affected by ESRD?
- many medications are excreted by the kidneys. If the kidneys are not working properly, medication levels can become toxic.
- Nursing Problem: toxicity and increased side effects from drugs
How is the regulation of BP affected by ESRD?
- the regulation of the RAA system is off
- Nursing problem: hypertension - potential for stroke, blindness, MI
How is the regulation of Vitamin D affected by ESRD?
- Vitamin D is activated in the kidneys. Activated Vit D helps regulate how Ca is absorbed, used and stored in the body.
- Nursing problem: osteoporosis - risk for injury,alteration in comfort
- Nursing problem: hypocalcemia - seizures
How is erythropoietin production affected by ESRD?
- Erythropoietin is produced by the kidneys. If the kidneys are not working correctly there will not be correct production of RBCs in the bone marrow
- Nursing problem: decreased tissue perfusion (arterial), fatigue, activity intolerance
What is the AAA Triad?
- Azotemia: increased blood urea nitrogen and serum creatinine levels suggestive of renal impairment by without outward symptoms of renal failure. UNABLE TO REMOVE THESE FROM THE BLOOD IN RF
- Acidosis
- Anemia
Normal BUN and Creatinine levels
BUN = 5-20 mg/dL
Creatinine = .5-1.5 mg/dL
Normal pH level
7.35 - 7.45
Normal Hgb and hct levels
* Hgb = 15 g/dL
* hct = 45%
- Hct can be decreased in renal failure due to hydrationstatus or b/c the RBCs are actually lower
What are the kidneys not able to remove from the blood in renal failure?
BUN and creatinine
How are BUN and creatinine kept low during ESRD?
- Protein intake is controlled (.8-1.5 g/kg)
- Calories are provided by CHO
- Avoid dieting
- Avoid catabolic states
- Avoid GI bleeding
- Dialysis
* ESRD PTS NEED TO EAT A VERY STRICT DIET B/C OF THE AFFECTS THAT COULD HAPPEN TO THEIR BUN AND CREATININE - eating too much or too little can increase the BUN and creatinine
What is acidosis and how does it occur?
- hydrogen and ammonia in serum - decreased bicarbonate reabsorption
- end products of protein metabolism
hyperkalemia (K/H shift)
How is acidosis corrected?
* bicarbonate PO or IV
* Shohl's solution
* Give IV slowly to prevent hypocalcemia and tetnay
- Giveing a lot of bicarbonate by IV can cause it to combine with Ca which can cause tetany
* Keep protein and K controlled in diet
* Dialysis
Which ABG in ESRD?
pH 7.5 pCO2 30 HCO3 21
pH 7.31 pCO2 50 HCO3 25
pH 7.48 pCO2 45 HCO3 28
pH 7.33 pCO2 34 HCO3 20
- 1 and 3 are out b/c this is alkalosis
- 2 is respiratory because of the increased pCO2
- ANSWER = 4
What is anemia and how does it occur?
- Erythropoietin production is lost
- shortens life span
- limited intake of protein
- bone marrow suppression
- loss of blood from dialysis or GI tract
how is anemia corrected/managed?
* minimize blood loss with repeated tests
* avoid blood transfusions or use sparingly (transfusions decreases the success of a transplant)
- eat iron rich foods (ferrous sulfate and folic acid/B9)
- human recombiant EPO or Procrit (helps stimulate RBC production)
- androgen hormone
Nursing goals of the pt with ESRD
- maintain homeostasis (with diet and dialysis)
- prevent complications
- teaching for discharge (learn to care for themselves)
- support life style changes
- quality of life issues
- ethical issues
- financial issues
ESRD nursing diagnosis: At risk for medication toxicity
* medication dosing amounts will most likely change for a person with ESRD
* Decrease dosing
* Check for K and Mag in all meds
- Mag = 1.5 - 2.5 mg/dL
- Increased K is not good, but increased Mag can cause an alteration in consciousness