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26 Cards in this Set
- Front
- Back
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captopril
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ACEI
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enalapril
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ACEI
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lisinopril
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ACEI
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quinapril
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ACEI
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candesartan
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ARB
blocks AT1 receptor, thereby blocking action of AngII and AngIII DOES NOT REDUCE BREAKDOWN OF BRADYKININ |
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losartan
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ARB
blocks AT1 receptor, thereby blocking action of AngII and AngIII DOES NOT REDUCE BREAKDOWN OF BRADYKININ |
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valsartan
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ARB
blocks AT1 receptor, thereby blocking action of AngII and AngIII DOES NOT REDUCE BREAKDOWN OF BRADYKININ |
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bumetanide
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loop diuretic (LH)
increase Na excretion by 25% |
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furosemide
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loop diuretic (LH)
increase Na excretion by 25% |
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torsemide
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loop diuretic (LH)
increase Na excretion by 25% |
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metolazone
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thiazide-like diuretic
lesser effects, esp in renal patients |
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thiazide diuretics
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thiazide-like diuretic
lesser effects, esp in renal patients |
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bisoprolol
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betablocker
reduces sympathetic adaptive effects of heart failure B1 selective |
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carvedilol
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betablocker
reduces sympathetic adaptive effects of heart failure B1, B2, A1 nonselective |
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metoprolol
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betablocker
reduces sympathetic adaptive effects of heart failure B1 selective |
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digoxin
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cardiac glycoside
increases cardiac contraction by increasing free Ca: decreases reflex SNS activity and increases renal perfusion inootropic benefits, effects on sympathetic nerves and kidney ARRHYTHMIA |
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digitalis
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cardiac glycoside
inootropic benefits, effects on sympathetic nerves and kidneyincreases cardiac contraction by increasing free Ca: decreases reflex SNS activity and increases renal perfusion |
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eplerenone
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aldosterone antagonist
reverses structural effects, water retention severe heart problems, lv problems after MI HYPERKALEMIA reduces mortalitity in III and IV with an ACEI |
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spironolactone
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aldosterone antagonist
reverses structural effects, water retention severe heart problems, lv problems after MI HYPERKALEMIA reduces mortalitity in III and IV with an ACEI |
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isosorbide dinitrate
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vasodilator: VEINS
increases CA flow used as combo w. hydralazine Toxicity: headache/hypotension, tolerance |
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hydralazine
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Vasodilator: ARTERIAL
*reduces renal vasculature resistance combo with isosorbide dinitrate Toxicity: GI, headahce |
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nitoglycerine
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vasodilator: NO source
VENOUS CAPACITANCE uses: l. sided HF due to MI Toxicity: tolerance, headache |
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Dopamine
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B AGONST A AGONIST (high infusion)
B: stimulated cardiac contractility A: VC to support a dropped Pa Toxicity: tachycardia can provoke MI in patients with CAD |
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Dobutamine
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B-agonist (nonselective)
uses: systolic dysfunction Iontropic effect predominates, little change in HR, VD increases flow to renal and heart. Tolerance develops |
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inamrinone
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cAMP phosphodiesterase inhibitor
increase cAMP: stimulate contraction and accelerate relaxation use: advanced heart failure |
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milrinone
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cAMP phosphodiesterase inhibitor
increase cAMP: stimulate contraction and accelerate relaxation use: advanced heart failure Better side effect profile, more selective for PDE3, shorter half life |
