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14 Cards in this Set

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  • Back
What is heart failure?
Inability of the heart to pump enough nutrients to tissues
What happens to the heart during heart failure?
Decrease in contractility and an increase in pre-load, after-load and heart rate
2 basic ways of treating heart failure?
-decrease workload
-increase contractility
What agents are used to increase contractility
Positive inotropic agents
How do positive inotropic agents work?
- Increase influx of Ca
- B adrenoreceptor agonist
Problem with positive inotropic agents?
- Don't improve survival
- can cause arrhythmias
What agents used to decrease workload?
- B blockers
- Diuretics
- Vasodilators
ACE inhibitor is and works how?
- vasodilator
- prevents actions of angiotensin II
What are the actions of angiontensin II?
vasoconstriction, increase aldosterone release which increases Na+ retention --> increasing water retention (thus blood vol)
Ca entry blockers is and works how?
- Vasodilator, decreases contractions and slows AV conduction
What are diuretics used for?
Treating odema associated with heart failure
How do diuretics work?
Increase Na+ excretion thus increase urine vol
Adverse effect of diuretics?
Hypokalemia which can lad to hypoglycemia
Example of a diuretic
Fruzemide (loop diuretic - most effective most side effects)