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48 Cards in this Set

  • Front
  • Back
what are the layers for arteries?
intima
media
adventitia
how are veins different from arteries?
larger diameter and lumina
thinner, less organized walls
more prone to irreg dilation, compression adn inflammation
valves in larger vessels push bl against gravity.
~how thick is a capillary?
only one endothelial cell layer thick
feature that causes slow bl flow?
Very large cross sectional area
~diameter of capillary?
rbc diameter
What is the endothelium involved with?
Blood tissue interchange (permeability)
Control of coagulation and clotting
Vessel repair
Modulation of blood flow
Regulation of inflammation
Regulation of cell growth
Oxidation of low-density lipoprotein
greater than _____ bpm = tachycardia
100
less than ______ bpm = bradycardia
60
systole = contraction and causes?
3
Walls of the right and left ventricles contract
Pump blood into pulmonary artery and aorta
Tricuspid and mitral valves close
diastole = dilation and causes?
3
Ventricle walls relax and blood flows into the heart from venae cavae and pulmonary veins
Tricuspid and mitral valves are open
Pulmonary and aortic valves close at
During diastole, where does the bl flow in from?
from venae cavae and pulmonary veins
which valves are open in diastole?
Tricuspid and mitral valves are open
The amount of blood in ventricle at the end of _______ is called preload
diastole
preload: ___ venous return, more ____ of ventricle, more rapid and ______ ventricular contraction
more
stretching
forceful
what is the Frank-Starling relationship?
Within limits, if more venous return, more stretching of ventricle, more rapid and forceful ventricular contraction
in afterload what is the main portion?
arterial pressure
what factors are involved in afterload?
arterial pressure
thickness of bl
elasticity of vessels
contractility is also known as?
inotropy
Force of ventricular contraction independent of _____ ______
Force of ventricular contraction independent of loading conditions
what is normal cardiac output?
normal is 5-6 L/min
how do you measure the cardiac index?
Cardiac output divided by body surface area
what is the normal cardiac index?
Normal is 2.6 – 4.2 L/min/m2
From SA node, electrical impulse passes simultaneously to _____ and to right and left ___ causing them to _____
From SA node, electrical impulse passes simultaneously to atrioventricular node (AV node) and to right and left atria causing them to contract
where does the bundle of HIS divide into R and L
Within interventricular septum
what causes the walls to contract?
Purkinje fibers
what effects does the sympathetic system have on the heart?
Increased heart rate through ß-1 receptors of SA and AV nodes
Shortened conduction time through AV node
Innervates atria and ventricles
Increased contractility of cardiac muscle by increasing calcium
Therefore increased cardiac output
what effects does the parasympathetic system have on the heart?
Decreased heart rate through SA and AV nodes
Increased conduction time through AV nodes
Innervates atria by vagus nerve
Little to no influence on ventricles
Little effect on contractility
Slight decrease
Therefore decreased cardiac output
the resting membrane potential is ____ inside the cell and ______outside of cell
neg
pos
how many na+ are exchanged for every 2 K?
3
Na + goes ___ the cell
(RMP)
out
K+ goes __ the cell
(RMP)
into
which ion leaks easier out?
K
Potassium leaks out ____ than sodium leaks ___
easier
in
in depolarization, stimulus causes __________ of charges.
neutralization
Na+ gates open during _________
Depolarization
In Depolarization, cell membrane is
+
In Repolarization, Na+ channels are ____.
closed, closing
In Repolarization, K+ channels are ____.
open
during repolarization, cell becomes excessively ___ and gates ____
neg
close
>________Americans die of CVD each day
> 2,200 Americans die of CVD each day
If all major CVD was eliminated estimated that life expectancy would increase by __ years
7
classic signs of heart dz
Pain in chest, jaw, neck, back, shoulders or arms
Dyspnea
Palpitations or skipped beats
Syncope
Edema
which signs are for women, and often mistaken for something else?
jaw pain
back pain
Dyspnea
Ocular findings can indicate increased __ of __
risk of CVD
what is associated with 2X rate of death from CVD?
Avanced amd
Retinopathy (diabetic or non) increases risk of heart disease ______x
2 – 6 X
CVD can cause ocular symptoms
Transient Ischemic Attacks (TIAs)
Retinal vascular changes / CRVO
Ocular ischemic syndrome
Cardiovascular meds can cause ocular adverse rxns:
2
Warfarin, Amiodarone