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50 Cards in this Set

  • Front
  • Back

Pathogenesis

Sequence of events involved with changes related to disease there the signs or symptoms

Diagnosis

identification of a specific disease with signs and symptoms and diagnostic test

Prognosis

Your chance of recovery

Sequelae

The potential unwanted outcomes of the permanent condition ex..paralysis following a stroke recovery

Comorbidity

Having two or more things going on with your body system

Pathology

A branch of medicine that investigates the essential Nature of disease especially pertaining to a body tissues and organs

Clinical pathology

Refers to the laboratory methods of diagnosis In pt refers to the effects of the disease on function

Systemic effects of acute inflammation

Is the initial response of tissue injury such as bacterial infections necrosis and can lead to abscesses

Symptoms of acute inflammation

Fever, tachycardia, hypermetabolism stay ... all of these affects can cause changes in the blood such as elevated serum protein levels

Systemic effects on chronic inflammation

Is the result of persistent injury or repeated episodes of acute inflammation, infection, cell mediated immune response, and foreign body reactions.

Tissue response to injury can cause accumulation of lymphocytes, plasma cells, and macrophages this causes production of fibrous connective tissue

Fibrosis

Cause tissue damage and loss of function

Fibrotic tissue

Light gray and has a dence firm texture

Symptoms of chronic inflammation

Low-grade fever, malaise, weight loss, anemia, fatigue, leukocytosis, lymphocytosis,

Systemic effects on neoplasms

Malignant tumors or cellular growth by their destructive nature of uncontrolled cell proliferation and spread

May produce both local and systemic effects

Side affects of neoplasms
Weight loss, muscle weakness, anorexia, anemia, coagulation disorders
I continued spread of cancer can cause what

Bone erosion, liver damage, G.I. tract damage, pulmonary obstruction, vascular obstruction

ADR

Adverse drug reaction

Adverse drug reactions

Are unwanted and potentially harmful side effects produced by medicine

Can be life-threatening, cause side effects, can have a therapeutic effects that means it works

Signs and symptoms of an adverse drug reaction

Mild, moderate, severe, or lethal

Mild reaction

Altered taste, anxiety, dizziness, headaches, shakiness, and mild vomiting

Moderate reaction

Abdominal cramps, dysphasia which is shortness of breath, and increase or decrease in blood pressure, tachycardia, persistent vomiting

Severe reaction

Arrhythmia, seizures, laryngeal Adema, very low blood pressure, cardiopulmonary arrest

Chronic reversible cell injury

Atrophy, hypertrophy, meta plasma, displays is

atrophy

smaller

hypertrophy

bigger

what are the phases of healing

Hemostasis, inflammation, proliferation, remodeling

hemostasis

involves an immediate vasoconstriction, results in clotting or a hematoma

What are the two types of tissue healing?

Tissue regineration and tissue repair

tissue regineration

regrowth of original tissue

tissue repair

healing where it leaves scar tissue behind

True or false... tissue healing occurs from both tissue repair and tissue regeneration

true

reversible cell injury

occurs when the stressor is sufficiently small in magnitude or duration.



cell is able to recover homeostasis after removal of stress



adaptations may take place to allow the cell to function in an altered environment

acute reversible cell injury

cells react to injuries stimuli by changing their steady state to continue normal function

acute injury caused by altered ion homeostasis

increases intracellular ions or dissolve particles



sodium and calcium



influx of extra cellular fluid into the cell



swelling leads to less energy production



ph of the cell becomes acidic



can recover if cell nucleus remains intact

proliferation in healing

migration or repair lasts usually 3-20 days



the purpose is to close the wound and give strength

__________ is used in the proliferation stage. This is what forms the initial scar.

collagen

type 1 collogen

very strong, found in all body tissues

type 2 collogen

thin fillaments, found in cartilage

type 3 collogen

found in newborns and healing tissue

remodeling in healing

the longest healing phase, may continue up to a year...ex...like fixing up your home it takes a while

acute inflammation in healing

2-5 days and begins once a blood clot forms



inflammation breaks down and removes dead cells



inflammation helps prepare the site for healing

what are some factors that affect healing?

age, growth, and vascular sufficiency



psychological, emotional, spiritual, co-morbidities



substance abuse



nutrition



infection



type of tissue

What are the mechanisms of cellular injury?

ischemia (poor circulation)



infectious (viral)



immune reactions



genetic factors (sickle cell anemia, down syndrome, hunting tons)



mechanical factors (tension and compression)



chemical factors (iron deficiency)



What are the signs of irreversible cellular injury?

necrosis and rupture in the cell wall

PT promotes healing in inflammatory stage

TREATMENT: PRICE



GOAL: PREVENT NEW TISSUE DAMAGE

PT PROMOTES HEALING IN PROLIFERATION STAGE

GOAL: PREVENT NEW TISSUE DISRUPTION, EXCESSIVE ATROPHY, TISSUE ADHESIONS, GUIDE THE FORMATION OF NEW COLLEGEN



TREATMENT: PROTECT, LOW STRESS, MODALITIES, EXCERCISE



PT PROMOTES HEALING IN REMODELING STAGE

GOAL: OPTIMISE TISSUE FUNCTION



TREATMENT: STRETCH, STRENGTHEN, AND GAIT TRAINING

METAPLASIA

WHEN A TISSUE CHANGES INTO A DIFFERENT KIND OF ADULT TISSUE..HINT META CHANGES LIKE METAMORPHISIS

WHY SHOULD THE PTA CONSIDER SYSTEMIC FACTORS WHE PROVIDING LOCAL INTERVENTIONS

IF THEY HAVE A SYSTEMIC FACTOR YOU COULD CAUSE MORE INJURY IF THEY ARE FACING COMORBIDITIES


LEUKOCYTOSIS AND LYMPHOCYTOSIS ARE SYSTEMIC EFFECTS OF WHAT TYPE OF INFLAMMATION?

CHRONIC INFLAMMATION