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17 Cards in this Set

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  • Back
What is an aura?
A headache is preceded by visual symptoms
What causes a migraine?
Dilation and Inflammation of intracranial blood vessels
CGRP (promotes/inhibits) a migraine while 5-HT (promotes/inhibits) a migraine.
promotes
inhibits
What is abortive therapy?
Goal to eliminate headache pain after a migraine has begun
What are unique drugs to treat a headache?
Ergot Alkaloids
What do ergot alkaloids do?
Agonist activity at 5-HT and block inflammation
Ergotamine is a _______.
Ergot alkaloid
What is an overdose reaction to ergot alkaloids called?
Ergotism
What are the symptoms of Ergotism?
Ischemia and cold extremities
Ergot Alkaloids are safe during pregnancy.
T or F
False
Category X
Dihydroergotamine is similar to _____.
Ergotamine
Serotonin Agonists are also known as _____.
Triptans
What is the prototype of the triptans?
Sumatriptan
What are adverse effects of Sumatriptan?
Unpleasant Chest symptoms
Risk Category C
Coronary Vasospasm
What is prophylactic therapy?
Goal to reduce the frequency and intensity of attacks
What are some prophylactic drugs for headache?
Beta Blockers- Propranolol
TCAs- Amitriptyline
Antiepileptic Drugs- Divalproex and Topiramate
Estrogens are used to treat menstrual migraines.
T or F
True