Hdm Week 14 Extra

Front 1

5 drugs that target bact. cell wall synthesis:

Back 1

1. B-lactams

2. glycopeptides

3. bacitracin

4. Cycloserine

5. Phosphonomycin

Front 2

3 ways to combat B-lactams:

Back 2

1. B-lactamases, which alter the drug

2. alternative PBP's

3. (only GN bact. can alter the uptake of B-lactams)

Front 3

best way to combat glycopeptides:

Back 3

change target to D-Ala-D-Lac

Front 4

8 drugs that target bact. translation:

Back 4

1. aminoglycosides

2. tetracyclines

3. macrolides

4. lincosamides

5. streptogrammins

6. Oxazolidinones

7. fusidic acid

8. mupirocin

Front 5

2 ways to combat aminoglycosides:

Back 5

1. inactivate the drug with APH, AAC, ANT

2. altered membrane pot.

Front 6

2 ways to combat tetracyclines:

Back 6

1. Ribosomal Protection Proteins (RPP's)

2. efflux

Front 7

best way to combat macrolides, lincosamides, and streptogrammins =

Back 7

MLSB

- a form or RNA methylation

Front 8

best way to combat oxazilidinones =

Back 8

alter the drug target via cfr - rare

Front 9

best way to combat fusidic acid =

Back 9

alter the target - FusA mutations

Front 10

best way to combat mupirocins =

Back 10

alter tRNA synthetase (target)

Front 11

best way to combat quinolones =

Back 11

gyrAB or porCE mutations (target)

Front 12

best way to combat rifamycins =

Back 12

rpoB mutations

(mutations in the RNAP target)

Front 13

best way to combat trimethprims (sulfa) =

Back 13

DHFR mut.

Front 14

3 prodrugs:

Back 14

1. nitrofurantoin

2. metronidazole

3. pyrazenamide

Front 15

best way to combat nitrofurantoin =

Back 15

loss of nitroreductase (target)

Front 16

best way to combat metronidazole =

Back 16

loss of nitroreductase (target)

Front 17

best way to combat pyrazenamide =

Back 17

alter PuCA

Front 18

2 NA inhibitors:

Back 18

1. Zanamivir

2. Oseltamivir

Front 19

influenza virus serotypes are determined *exclusively* by:

Back 19

HA

Front 20

M avium infection is a concern for:

Back 20

HIV patients

Front 21

one great combo to combat bact. = B-lactam +

Back 21

aminoglycoside

Front 22

what kind of vaccine is MMR?

Back 22

live, attenuated

Front 23

Strep pyogenes is NOT:

Back 23

a latent organism in the body

Front 24

which is more exterior, the S-layer or the capsule?

Back 24

the CAPSULE

Front 25

water would not wash away the purple die, but would affect:

Back 25

the red dye binding

=> both would be purple

Front 26

viruses that belong to the same serotype are bound by:

Back 26

the same kinds of AB's

Front 27

which vitamin prevents measles complications?

Back 27

vitamin A

Front 28

what does Rhogam do?

Back 28

as an AB, it binds the Rh antigen and masks it from the mom's AB's => protects the baby

Front 29

what does daptomycin target?

Back 29

bact. plasma membranes

- it's a lipopeptide

Front 30

which kind of cells release Type II interferons?

Back 30

*immune* cells

Front 31

which bact. secretes H2O2?

Back 31

Mycobact. pneumonia

Front 32

which bact. secretes hydrolytic enzymes?

Back 32

Strep pyogenes

Front 33

what's a unique virulence factor of Strep pneumoniae?

Back 33

pneumolysin

Front 34

what organism do Prevnar13 and Pneumovax23 target?

Back 34

Strep pneumoniae

Front 35

which bact. are conjugate viruses useful for, particularly in children?

Back 35

Haemophilus influenza (bact)

Front 36

what kind of virus is the rubella virus?

Back 36

togavirus

Front 37

what kind of cells does a measles virus infect really well?

Back 37

immune cells