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9 Cards in this Set
- Front
- Back
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What is the structure of HCG like?
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A glycoprotein w/ 2 subunits
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what are the 2 subunits of HCG?
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alpha - shared with FSH/GH
beta - the component unique to HCG |
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What produces HCG?
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placenta
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What fluids is HCG found in?
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Serum - intact HCG
Urine - free Beta units |
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What are the functions of HCG?
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1. To maintain the corpus luteum.
2. To induce steroid synthesis in the fetus. |
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How is HCG prodcued timewise in pregnancy?
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1. Reaches detectable levels in serum w/in 1 wk of period missed.
2. Rises rapidly 3. Falls during 2nd trimester |
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List 5 cases in which HCG production is abnormal.
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1. Hydatidiform mole
2. Choriocarcinoma 3. Testicular tumors 4. Ectopic HCG production 5. Non-trophoblastic tumors |
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Which abnormal case is benign?
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Hydatidiform mole
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List 4 types of assays for HCG
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1. Bioassay
2. Immunoassay (1st gen) 3. Radioimmunoassay 4. Immunoassay (2nd gen) |
