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91 Cards in this Set
- Front
- Back
Evidence-based practice is the utilization of
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-research evidence in combination with
-clinical expertise and -patient preferences |
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PICO format for asking clinical questions =
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P= patient population of interest
I = Intervention of interest C = Comparison of interventions or groups of patients O = Outcome of interest |
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Evidence Based Practice
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Is the use of some or many results of clinical trials on a topic to improve quality and outcomes for patients.
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The five steps of the nursing process:
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Assessment
Nursing Diagnosis Planning Implementing the plan Evaluating |
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Example of a properly written Nursing Diagnosis
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Activity intolerance
related to insufficient oxygenation secondary to decreased cardiac output and pulmonary congestion, as manifested by weakness, fatigue, shortness of breath upon minimal exertion and patient’s statement ‘I feel too weak to do anything.’” |
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Clinical Pathways
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Are over-arching plans that direct the whole healthcare team on what to do in patients with similar needs/diagnoses
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Older Adults
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Young-old 55-75
Old-old 75 and up. |
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Ageism:
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This is a term that means discrimination against old people like “racism”.
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Erikson’s stages
Intimacy vs. Isolation: 18 - 34. |
Love relationships: The young adult must develop intimate relationships or suffer feelings of isolation
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Erikson’s stages
Generativity vs. Stagnation: 35 - 60 |
Parenting: Each adult must find some way to satisfy and support the next generation. Not meeting this goal makes people become pre-occupied with their own aging.
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Erikson’s stages
Ego Integrity vs. Despair: 60 - death |
Reflection on and acceptance of one's life: This goal comprises a life review which arrives at acceptance of oneself as-one-is, and feeling fulfilled. Not meeting this goal leaves those persons in despair. This can mean the difference of meeting death with anxiety or acceptance
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Elder Abuse
Typical abuser profile: |
Is a family member 9/10ths of time
Usually is an adult child of the victim Is still dependent on the victim Usually has a history of violence Often unemployed May be abusing substances or mentally ill |
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6 stages of change as theorized by Dr. James Prochaska
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Precontemplation
Contemplation Preparation Action Maintenance Termination |
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Stress
General Adaptation Syndrome (GAS) |
There are 3 stages to this syndrome
1. Alarm: sympathetic NS is is activated. This upsets the body’s homeostasis 2. Resistance: This is where the person makes some effort to adapt by taking action. 3. Exhaustion: Results when adaptation doesn’t occur. The person has used all resources and may become sick or die. –This occurs only with severe stressors. |
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Stress
Lazarus transaction theory: |
says that the amount of stress is relative to the perceived threat. Emotions heavily influence idea of stress
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Stress certainly will happen?
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Hypothalamus responds to pain, blood pressure changes and input from the Limbic system from emotions.
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Stress the Hypothalamus will have what effect (NS)
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It is the primary player in the stress response because it can modulate
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Stress chemicals released by the body
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Cortisol increases glucose (fuel) in the blood and inhibits inflammation from injuries.
Endorphins blunt pain response and can elevate/stabilize the mood. ADH reabsorbs water from the urine keeping blood volume and pressure up. Epinephrine increases heart rate and respiratory rate, dilates airways, and increases reaction times. |
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Stress, Bad effects of
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Chronic stress can suppress the immune system causing susceptibility to illness (effect of cortisol).
It can cause atrophy of the hippocampus resulting in memory impairment (cortisol). It is a factor in heart disease and heart attacks (effects of cortisol, epinephrine and ADH). It can cause osteoporosis and abdominal obesity (effect of cortisol). |
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Stress, Pain can make you sicker
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Pain is stressful and can prolong the stress response.
The more pain a patient has, the more likely that person is to become sicker or heal more slowly. Morale: Adequate pain control is important in all patients. |
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Kidneys
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1.2 liters of blood flows through the kidneys per minute
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Kidney
The glomerulus is like a tiny coffee filter |
It allows the liquid part of the blood to pass through without letting the large particles out (like blood cells and protein)
Normal GFR is around 125 ml per minute. |
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GFR
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A GFR of less than 60 is generally the magic number below which you need to question what drug dosing is occurring
Creatinine is a useful indicator of kidney function If the creatinine is above 1.5 you need to ask yourself if the doses of drugs you are giving are correct. |
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Chronic Renal Failure
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presence of kidney damage of a GFR of less than 60ml per minute for 3 months or more.
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end stage Renal Failure
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End stage renal disease (requiring dialysis) occurs when the GFR drops to below 15 ml/min.
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Other things the kidney does
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It regulates body fluid balance by responding to antidiuretic hormone.
ADH makes the reabsorption part of the kidney (distal convoluted tubules) open up and let water back into the blood, increasing blood volume and pressure. Aldosterone causes the distal tubule to reabsorb sodium and water and get rid of potassium in trade. The distal tubule is the part of the nephron that conserves bicarbonate and secretes hydrogen ions to maintain appropriate pH. |
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Other things the kidney does
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It makes erythropoietin, the stuff that causes the bone marrow to make red blood cells.
It activates vitamin D to make it useful to you. It secretes renin which causes a Rube Goldberg like cascade that makes you retain water and sodium, increasing the ECF and raising the blood pressure |
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Normal adult urine output
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Urine output should be 1500 milliliters a day.
Urine goes into the bladder via the ureters where it is dispatched. 200 – 250mls of urine in the bladder causes the urge to urinate. Discomfort starts at around 500mls. The average bladder holds between 600 and 1000 mls. |
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Urinary tract infections (UTIs)
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1/3rd of deaths from gram-negative sepsis occurred from urinary tract infections
E. Coli is the most common bacteria to cause UTIs. In addition to E. Coli, Pseudomonas is a common infecting organism. Pseudomonas has been found colonizing and corroding airplane fuel tanks. It is a tough and very dangerous organism. Urinary catheter caused infections are the single most common hospital infection |
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Azotemia
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–buildup of nitrogenous wastes due to inability of damaged kidneys to excrete it
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Uremia
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-describes the multiple symptoms resulting from the buildup of urea and other wastes in the blood
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Oliguria
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–the decrease of urinary output to less than 400ml per day (or about 15ml per hour –the number at which to worry)
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There are 3 main regions from which kidney failure precipitates
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Prerenal –means a damagingly-low blood supply to kidneys has occurred
Intrarenal –describes processes happening within the kidney itself that creates damage Postrenal is basically a urine outlet problem/obstruction that damages kidneys |
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kidney Waste excretion problems
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Patient develops uremia -headaches, nausea, vomiting lethargy and even seizures as nitrogenous wastes increase (Blood Urea Nitrogen or BUN)
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kidney Waste excretion problems
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Insulin resistance occurs or worsens in the case of those with DM. the cause is unclear as yet. High blood sugars can result (hyperglycemia)
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kidney Waste excretion problems
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Uremia can make insulin last longer in the body, creating problems with low blood sugar as well
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kidney Electrolyte imbalances
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Hyperkalemia results as kidneys can’t excrete it. Fatal heart arrhythmias can occur (remember capital punishment?) potassium consumption may be restricted.
Sodium can be low but this is deceptive. As as the person can’t excrete excess sodium it holds onto water at a great rate and produces actually a dilutional hyponatremia. Sodium must be restricted Hypermagnesemia can occur if person takes laxatives like MOM. The kidney can’t excrete excess. |
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kidney Metabolic Acidosis
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Inability to excrete ammonia (in form of urea) can cause acidosis
Kidney also can’t reabsorb bicarbonate and combined with the destruction of bicarbonate from normal buffering it falls to a low state between 16-20 meq/L. Bone demineralization takes over some of the buffering capacity |
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kidney Blood disorders
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Anemia -The kidney no longer makes adequate amounts of erythropoietin to stimulate red blood cell production.
Bleeding –impaired platelet function and clotting factor release can increase the incidence of bleeding in uremia Infection -White blood cells become impaired and can’t respond to infections as well. Chemicals that mediate the inflammatory response are diminished as well due to dysfunctional neutrophils and monocytes. |
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kidney Cardiovascular
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Hypertension occurs due to frequent volume overload and is aggravated by sodium retention.
The kidneys can’t excrete sodium or water and large amounts of fluid consumed is retained. Stroke from increased atherosclerosis Heart attacks and dysrhythmias occur from electrolyte imbalances and atherosclerosis |
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Kidneys
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1.2 liters of blood flows through the kidneys per minute
|
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Kidney
The glomerulus is like a tiny coffee filter |
It allows the liquid part of the blood to pass through without letting the large particles out (like blood cells and protein)
Normal GFR is around 125 ml per minute. |
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GFR
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A GFR of less than 60 is generally the magic number below which you need to question what drug dosing is occurring
Creatinine is a useful indicator of kidney function If the creatinine is above 1.5 you need to ask yourself if the doses of drugs you are giving are correct. |
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Chronic Renal Failure
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presence of kidney damage of a GFR of less than 60ml per minute for 3 months or more.
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end stage Renal Failure
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End stage renal disease (requiring dialysis) occurs when the GFR drops to below 15 ml/min.
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Other things the kidney does
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It regulates body fluid balance by responding to antidiuretic hormone.
ADH makes the reabsorption part of the kidney (distal convoluted tubules) open up and let water back into the blood, increasing blood volume and pressure. Aldosterone causes the distal tubule to reabsorb sodium and water and get rid of potassium in trade. The distal tubule is the part of the nephron that conserves bicarbonate and secretes hydrogen ions to maintain appropriate pH. |
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Other things the kidney does
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It makes erythropoietin, the stuff that causes the bone marrow to make red blood cells.
It activates vitamin D to make it useful to you. It secretes renin which causes a Rube Goldberg like cascade that makes you retain water and sodium, increasing the ECF and raising the blood pressure |
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Normal adult urine output
|
Urine output should be 1500 milliliters a day.
Urine goes into the bladder via the ureters where it is dispatched. 200 – 250mls of urine in the bladder causes the urge to urinate. Discomfort starts at around 500mls. The average bladder holds between 600 and 1000 mls. |
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Urinary tract infections (UTIs)
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1/3rd of deaths from gram-negative sepsis occurred from urinary tract infections
E. Coli is the most common bacteria to cause UTIs. In addition to E. Coli, Pseudomonas is a common infecting organism. Pseudomonas has been found colonizing and corroding airplane fuel tanks. It is a tough and very dangerous organism. Urinary catheter caused infections are the single most common hospital infection |
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Azotemia
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–buildup of nitrogenous wastes due to inability of damaged kidneys to excrete it
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kidney Cardiovascular
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Hypertension occurs due to frequent volume overload and is aggravated by sodium retention.
The kidneys can’t excrete sodium or water and large amounts of fluid consumed is retained. Stroke from increased atherosclerosis Heart attacks and dysrhythmias occur from electrolyte imbalances and atherosclerosis |
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kidney GI ttract
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Ulcerations along the mucosa in the GI tract can occur from excess ammonia in the blood.
Patients can have GI bleeds from these ulcerations. Nausea vomiting and anorexia occur from built up toxins. Breath can smell like urine as these products are not excreted |
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kidney Nervous system
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Nerves become demyelinated from urea and the various other imbalances.
General depression of the CNS occurs resulting in lethargy, poor concentration, and irritability Seizures can occur. Coma can ensue from hypertensive encephalopathy Paresthesias –restless legs, burning sensation in the feet, “bugs crawling in skin” |
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kidney Skin & Musculoskeletal system
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Osteomalacia from bone demineralization using calcium to buffer acids occurs
Holes in bone can fill in with fibrous tissue resulting in osteitis fibrosa cystica Skin becomes yellow-gray from urinary pigments. Itching is common |
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kidney Management
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Restrict high potassium foods, limit potassium to 2-4 grams per day (cut out bananas, tomatoes ,yellow vegetables, oranges)
Limit sodium to between 2-4 grams per day (cut out canned soups, cured meats, pickled foods) Manage hypertension but avoid ACE inhibitors due to worsening the GFR Reduce phosphate by dietary modifications and by taking tums or other phosphate binders (limit ice-cream, and other dairy products) |
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kidney Peritoneal dialysis
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Infuses a dialysate into the peritoneal space.
The capillaries of the peritoneal cavity are used as the dialysis membrane A catheter is placed into the peritoneum A bag of 2 liters of dialysate is warmed and instilled The fluid is allowed to sit and absorb excess metabolic products and electrolytes It then is drained off and disposed of. Because dialysate has glucose to increase the osmotic gradient and pull out excess fluid, sometimes the glucose can get into the blood and cause hyperglycemia |
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kidney Peritoneal dialysis
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Drawbacks
Abdominal pain during infusions Protein loss Bacterial peritonitis Hyperglycemia Catheter infections Benefits Can do at home Can do at any hospital Less cardiovascular stress due to slower fluid shifts |
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Hemodialysis -Removes the blood and runs it through a dialysis machine
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Usually a fistula is placed in the arm connecting a vein and an artery
Blood is taken from the arterial side to dialysis machine and returned to the venous side of the fistula. Fistulas are usually made of synthetic material. They produce a vibration or “thrill” when working properly to agitate the blood and prevent thrombus formation. |
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Intracellular fluid or 1st space:
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is the sum of the fluid contained in each individual cell. 42% of body weight.
“First spacing” is nothing but normal fluid distribution. |
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Extracellular fluid or 2nd space:
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is what lies between the cells and what is in the blood stream. 17% of body weight.
“Second spacing” refers to interstitial edema usually of the type that makes the legs swell up. Fluid that goes here can be reabsorbed if correction of the underlying abnormality is corrected |
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Transcellular space or 3rd space:
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is the combination of the spinal fluid, GI tract, Pleural fluid, Joint fluid and Peritoneal fluid. 1L per person.
Vomiting and diarrhea can deplete the transcellular fluid in the GI tract resulting in replacement from fluid from the extracellular space. |
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Third spacing
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is a term you will hear commonly when fluid is pulled in to the peritoneal or pleural cavities from oncotic or hydrostatic pressure problems. This is body fluid that becomes unavailable for use.
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Types of pressure
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Osmotic: the pull a solute has for pure water will cause that fluid to expand and apply pressure to a cell or vessel wall.
Oncotic: the pull protein has for pure water will similarly cause the fluid volume to expand and apply pressure on cell or vessel walls. Hydrostatic: the pressure exerted by actual mechanical force such as from the heart pumping or lungs expanding. |
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when the blood pressure is low or the osmolality is high
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The hypothalamus is responsible for causing the pituitary to release Anti Diuretic Hormone to affect water conservation.
ADH does this by causing the renal tubules to reabsorb water (from the urine in the kidney) It also makes you thirsty. |
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Regulation of fluid balance -Aldosterone
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Aldosterone increases vascular volume.
It is regulated by the kidneys in response to blood flow. Aldosterone is the major mineralcorticoid made in the adrenal glands (sitting just above the kidneys) . Aldosterone is released when the blood pressure is low or the sodium is low. |
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Selected normal limit is for electrolytes
Sodium |
135-145 mEq/L
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Selected normal limit is for electrolytes
Potassium |
3.5-5.5 mEq/L
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Selected normal limit is for electrolytes
Calcium |
8.5-10.5 mEq/L
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Selected normal limit is for electrolytes
Magnesium |
1.5-2.5 mEq/L
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Selected normal limit is for electrolytes
Phosphorus |
2.5-4.5 mEq/L
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Selected normal limit is for electrolytes
Chloride |
96-106 mEq/L
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Water deficit /Hypernatremia
the concept of “too much sodium” and “water deficit” are nearly synonymous. |
Symptoms
Acute weight loss, oliguria, concentrated urine, weak rapid pulse, Low BP, dizziness especially upon standing, weakness, thirst, Contributing factors Vomiting, diarrhea, fever, excessive sweating without fluid replacement, Diabetes insipidus (insensitivity to vasopressin), careless hypertonic IV saline administration. GIVE 5% dextrose = isotonic |
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Water excess /Hyponatremia
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Symptoms
Acute weight gain, edema especially in the lower legs, JVD, crackles in the lungs, shortness of breath, high blood pressure, bounding pulse. Contributing factors Congestive heart failure, hypotonic IV fluid excess, SIADH (too much ADH), primary polydipsia (rare) Burns, Diarrhea, vomiting, Nasogastric suction, Diuretics. GIVE 3% Saline |
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5% Dextrose in 0.225 saline =
give? |
isotonic
provides Na , Cl +free water replace hypotonic losses + treat hypernatremia |
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5% dextrose in 4.5 or 9% Saline=
Give? |
hypertonic
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0.45% Saline =
give? |
hypotonic
provides free water + na , Cl use as maintenance solution no calories |
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0.9% saline =
give? |
isotonic used to expand intravascular volume and replaces extracellular fluid losses. contains na + cl
(carefull may causeintravascular overload + hyperchloremic acidosis |
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3.0% saline =
give? |
hypertonic
to treat hypoatremia give slowly may cause dangerous intravascular volume +pulmonary edema |
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Lactated ringer =
give |
Isotonic HAs no mgs
used for losses of burns + GI can be used for metabolic acidosis DONOT USE IN LACTiC ACIDOSIS |
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Potassium regulates
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intra-cellular osmolality by being exchanged for sodium (which water likes to follow)
Abnormal levels can cause heart arrhythmias |
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Low Potassium = HYPOKALEMIA
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Fatigue, anorexia, N&V, muscle weakness, hypoactive reflexes, paresthesias, leg cramps, polyuria, ileus, abdominal distension, Ventricular-fibrillation, Low BP
ECG: flattened T waves (low K+ means low T waves |
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High Potassium = HYPERKALEMIA
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Vague muscle weakness, Heart arrhythmias, flaccid paralysis, paresthesias, intestinal colic, Muscle cramps, irritability, anxiety
ECG: tall tented T waves (High potassium means high T waves) |
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maximum rate that potassium should be given IV is no more than
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20meq/hour
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Emergency treatment for hyperkalemia is
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administration of insulin and dextrose to force potassium back into cells. After this, a binding agent (Kayexelate) can be given orally to absorb it in the gut
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HYPERCALCEMIA
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Muscle weakness, constipation, anorexia, N&V, polyuria, polydipsia, hypoactive reflexes, lethargy, deep bone pain, pathological bone fractures, flank pain, calcium stones,
Emergency treatment is by rapid dilution of the blood by giving IV normal saline, and by special drugs |
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HYPOCALCEMIA
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Symptoms:
Numbness and tingling of the toes, fingers, circumoral region (aka paresthesias) Positive Trousseau’s and Chvostek’s signs, seizures, hyperactive reflexes |
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lungs Pleural effusion
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Is a buildup of the pleural fluid in the chest cavity around the outside of the lung.
It can happen from blocked lymph outflow from cancer From leakage of fluid from the blood in congestive heart failure Infection and inflammation |
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lungs When to suspect Pneumonia
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Sudden onset of:
Fever, chills, cough with purulent sputum and sharp pain with breathing (pleuritic pain) Dullness to percussion in an area Crackles on auscultation Increased fremitus (vibration with speech) |
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lungs Pleurisy
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Inflammation of the pleura
Hurts to breathe in. The pain is Sharp. Person breathes shallowly to avoid pain. |
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lungs Asthma meds
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albuterol inhaler reduces bronchospasm, with onset of wheezes
Corticosteroids reduce inflam Rinse mouth after inhaled steroids to prevent yeast infection (thrush) other drugs like cromolyn (Stabilizes mast cells) and Montelukast [singulair) (inhibits leukotrienes) |
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lungs Drugs for treating TB
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Four drugs at once are now being used to treat TB due to drug resistance.
Isoniazid Rifampin Pyrazinamide Ethambutol There are a number of combinations… Treatment may continue for 9 months |