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8 Cards in this Set
- Front
- Back
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what age group is most often affected by hairy cell leukemia?
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adults; the median age is 55
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what organs do the tumor cells in hairy cell leukemia usually go to?
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bone marrow and spleen; rarely do they go to the lymph nodes
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how do patients with hairy cell leukemia present?
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splenomegaly and pancytopenia
monocytopenia is characteristic of hairy cell leukemia |
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a patient present with pancytopenia and splenomegaly. a bone marrow aspirate is strongly TRAP positive. what is the diagnosis?
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hairy cell leukemia
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what is a dry tap? why does it occur?
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- when you do not get any marrow out of the bone during a bone marrow aspirate
- an increase in the reticular fiber count |
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what part of the spleen do hairy cells accumulate in?
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red pulp
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what is the immunophenotype of hairy cells?
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CD20, CD22, CD11c and CD103
also Annexin A1 which is specific for hairy cell leukemia |
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what is the prognosis for patients with hairy cell leukemia?
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good; this is an indolent disease and the patient may carry it for many years with no symptoms
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