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39 Cards in this Set

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Chromatin

Chromatin

The material the composes everything except bacteria. Protein RNA DNA

Hair


chromatins are in humans

Mutation

Mutation

The changing of the structure of a gene, results in a different form that may be passed down to next generation

Wolverine


many people have mutstions

Mutagen

An agent that cause genetic mutation

Radiation


radiation is a mutagen

Excision repair

A cellular mechanism that repairs damaged DNA

BER


excision repair occurs in humans

Sister chromatids

Either of the two copies that is formed by the copying of a chromosome

Duplicated chromosome


humans have sister chromatids

Centromere

Centromere

The point on a chromosome by which it's attached to a spindle fiber in cell division

Chromosome


centromeres are on chromosomes

Aneuploid

Having certain genes or chromosome regions present in extra or fewer copies than usual

Genes


aneuploids are unusual numbers

Prophase

The first stage of cell division, the chromosome becomes visible as paired chromatids

Cells


prophase is the first step

Metaphase

The second stage of cell division, chromosome becomes attached to spindle fibers

Cells


metaphase is the second step

Anaphase

The stage of meiotic or mitotic cell division chromosomes move away from one another

Cells


anaphase involves cells

Telophase

The last phase of cell division chromatids or chromosomes move to opposite ends of the cells, two nuclei formed

Cells


telophase is the last stage

(Mitotic) spindle (fibers)

The macromolecular machine that separates chromosomes into two daughter cells in mitosis

Chromosome


Spindle involved mitosis

Spindle poles

Spindle poles

Microtubule organizing center in yeast cells similar to the centrosome

Cells


spindle poles are organizers

Kinetochore

Kinetochore

The point on a chromosome by which it is attached to a spindle fiber in cell division

Cells


kinetochore is on a chromosome

Cyclins

All proteins associated with the cycle of cell division, thought to initiate processes of mitosis

Proteins


cyclins involved cell division.

Kinases

An enzyme that catalyzes the transfer of a phosphate group from ATP to a specific molecule

Protein


kinases involve ATP

Cell-cycle arrest

Cell-cycle arrest

The stopping of the cell cycle, termination

Cells


cell-cycle arrest isn't good

Cancer

The disease caused by the uncontrolled division of abnormal cells in apart of the body

Cells


cancer is very bad

Cell cycle

An ordered sequence of events in the life of a dividing eukaryotic cell

Yeast



Produces two new identical organisms




Mitosis

The process of distributing a copy of each chromosome to each new cell during eukaryotic cell division

Daughter cells



Sorting and distributing the chromosomes

Interphase

The period between divisions

During interphase, the individual chromosomes aren't visible in the nucleus



Growth and DNA synthesis

G1/G0

The first phase of the cell cycle

Prereplication



When cells stop dividing in G1, they enter G0

S

DNA synthesis

Replicator



Phase of the cell cycle

G2

Synthesizes specific types of RNA and proteins

Premitosis



Prepares cell for mitosis

M

A series of events that ensures each daughter cell receives one copy of each chromosome

Mitosis



Chromosomes are condensed and visible through a microscope

Restriction point

Once this point is passed the cell must go through the whole cell cycle

Point of no return



Occurs in G1, G0

Cytokinesis

Division of the whole cell

Cytoplasm divided



After cytokinesis each cell enters G1

Cytokinesis

Division of the whole cell

Cytoplasm divided



After cytokinesis each cell enters G1

Daughter cell

New created cell off of another cell

Parent having a child (daughter)



Mitosis provides each daughter cell with a replicant set of chromosomes as the parent cell

Cytokinesis

Division of the whole cell

Cytoplasm divided



After cytokinesis each cell enters G1

Daughter cell

New created cell off of another cell

Parent having a child (daughter)



Mitosis provides each daughter cell with a replicant set of chromosomes as the parent cell

Nucleotide base pairing

The structure of DNA

A+T, G+C



This depends in how many hydrogen bonds each nitrogen base can form with it's counterpart

Hydrogen bond

Holds together the strands of DNA in their double helix

A+T, G+C



The two strands have opposite orientations

Hydrogen bond

Holds together the strands of DNA in their double helix

A+T, G+C



The two strands have opposite orientations

Antiparallel

The arrangement of DNA structure

A divided highway



They are parallel but run in opposite directions

DNA polymerase

The enzyme that catalyzes the formation of the new DNA strands

The equivilant of copying from an older model



Uses one of the original strands as a template

Semiconservative

Replaces the old DNA double helix with two new ones

Half conservative



One strand of old DNA and one strand of new DNA

Chromosome

A tightly condensed structure wrapped by proteins

Extra chromosomes cause downsyndrome



Shape is visible only at mitosis

Histone

Family of basic proteins doing DNA work in the nucleus

Forms nucleosomes



Nuclear DNA is highly condensed and wrapped around histones