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32 Cards in this Set

  • Front
  • Back

CDC Diagnostic Criteria for PID

(a) Minimum
(b) Supportive
(c) Definitie

Sexually active female with pelvic or lower abdominal pain with no other identifiable cause for illness other than PID identified

Minimum criteria (1 or more of following on pelvic):
-Cervical motion tenderness
-Uterine tenderness
-Adenexal tenderness

Supportive:
-Temperature >38.3
-Cervical/vaginal mucopurulent discharge
-Elevated ESR/CRP
-Documented G/C on swab

Definite:
-Laproscopy
-Biopsy proven endometritis
-Transvaginal or MRI evidence of saplingitis, TOA
Risk factors for PID
Young age (15-25 years of age)
Multiple sexual partners
Cigarette smoking
Menses
Insertion of IUD within previous 3 weeks
Recent uterine instrumentation
African American
Indications for Admission in PID
Cannot exclude surgical emergency
Prengnacy
Not responding to oral therapy
Not reliable for outpatient treatment
Severe illness (vomitting, high fever)
Tubo-ovarian abscess
Initial treatment for PID

250 mg Ceftriaxone IM

plus 14 days of Doxy 100 BID and Flagyl 500 BID

Key points to differential ulcerative STI's

Description of lesions


- single or multiple


- painful or painless


- Indurated or soft


- Irregular or soft


- Evolution


Presence of Absence of adenopathy


Systemic symptoms

Most common ulcerative STI

Genital herpes

Primary herpes infection in patients without pre-exsisting antibodies

Vesicles -> PAINFUL shallow multiple grouped ulcers that may coalesce



Systemic symptoms



Bilateral midly tender non fluctuant adenopathy

DDX for ulcerative STIs

Herpes genitalis


Primary syphillis


Chancroid


Lymphogranuloma vereneum (LGV)


Molluscum contagiosum


Condyloma acuminata (genital warts)


Pediculosis


Scabies


Pyoderma


Trauma


Excoriations


Bechet's disease


Fixed drup eruption


Yeast infection


DDX for non-ulcerative STIs

Gonorrhea


Chlamydia


Nongonoccocal urethritis


Secondary or tertiary syphillis


Candidal vaginitis


Trichomoniasis


Bacterial vaginosis


Endometriosis

Recommended diagnostic test for herpes

PCR testing for HSV DNA



Consider serology if negative but high clinical suspicion

Syphillis causative organism and transmission

Treponema pallidum



A Spirochete bacterium



Transmission is via exposure of moist skin to an infected area

Syphilis Manifestations

Chancre

Solitary, PAINLESS papule that then ulcerates



Smooth raised edge with sharply defined borders and clean base

Non-Treponemal testing for syphillis

VDRL (Veneral disease research laboratory)


RPR (rapid plasma reagin) tests



Both are screening tests

Treponemal/Confirmatory testing

Microhemagglutination test for treponema pallidum (MHA-TP)



Florescent treponemal antibody absorption test (FTA-ABS)

Lymphogranuloma verenum

Causes by specific serotypes of Chalmyidia trachomatic



Small, PAINLESS, transient genital lesions



Followed by unilateral inguinal lymphadenitis (groove sign) mainly non fluctuant

Chancroid

Caused by Haemophilus ducreyi,


Multiple PAINFUL genital ulcerations and inguinal bubo formation

Criteria for "probable" diagnosis of chancroid

(1) One or more PAINFUL genital ulcers


(2) no evidence of T. pallidum infection


(3) the clinical presentation typical for chancroid


(4) HSV testing on the ulcer exudates are negative.

Granuloma inguinale (donovanosis)

Caused by Klebsiella granuomatis



Chronic, PAINLESS, progressive ulcerative lesions on the genitalia or perineum



Irregular, clean-based granulomatous ulcers that are highly vascular (giving the classic “beefy red appearance”)



CONDYLOMATA ACUMINATA

Anogenital warts causes by HPV

Characteristics of ulcerative STIs

Most common STI

Chlamyidia

Causes of nongonococcal urethritis other than chlamyidia

Ureaplasma urealyticum


Haemophilus vaginalis


Mycoplasma genitalium

Disseminated gonococcal infections

Causes by gonococcal bacteremia



More common in woman



Characterized by arthritis-dermaitis syndrome

Characteristics of vulvovaginitis by cause

Trichomoniasis

Causes by flagellated protozoan -> Trichomonas vaginalis



Bacterial vaginosis

Shift in normal vaginal flora towards polymicrobial infection with anaerobes

Amsel critieria for bacterial vaginosis

1. A thin, white homogeneous discharge that smoothly coats the vaginal walls.
2. Presence of clue cells in microscopic examination
3. A pH greater than 4.5.
4. A fishy odor to the vaginal discharge before or after the addition of 10% KOH (whiff test).

Conditions in DDX for vulvovaginal discharge/itching

allergic or chemical vaginitis


atrophic vaginitis


scabies,
pediculosis pubis (genital lice)


vaginal foreign bodies

Pelvic inflammatory disease

Infectious disease of female upper genital tract



Any combination of endometritis, salpingitis, peritonitis, and tubo-ovarian abscess

Summary of STI Treatment

DDX of rash on palm/sole

P - Psoriasis


A - Atopic dermatitis


L - Lips/Hand/Foot/Mouth Disease (coxsackie)


M - Menningococcemia


G - Gonnocococcemia


R - RMSF


E - Erythema Multiforme


A - Allergic/contact dermatitis


S - Syphillis (Secondary)


E - Eczema



+


Toxic shock syndrome


Graft versus host disease