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21 Cards in this Set

  • Front
  • Back
what is the definition of endometriosis?
presence of endometrial tissue outside of cavum uteri
what is the most common localisation of endometriosis?
pelvic
what are the three entities of endometriosis?
peritoneal

ovarian

deep-infiltrating
what are the two forms of endometriosis in the myometrium?
adenomyosis

and

adenomyoma
what are the most common localisations of endometriosis in descending frequency?
ligamentum rectouterinum 2/3

ovary, superficial 1/2

ovary, deep = endometrioma 1/5

Douglas space/ retrocervical 1/5
how common is deeply infiltrating endometriosis and where is it localised?
septum rectovaginale

and

intestine and urinary bladder
what is the age peak at diagnosis in endometriosis?
before age 30
what are risk factors for endometriosis?
strong familial clustering with RR = 7 among first degree relatives
what are pathogenetic hypotheses of endometriosis?
retrograde menstruation

endometrial affection is explained by metaplasia of invaginated coelomic epithelium

deeply infiltrating endometriosis is explained by metaplasia of Mullerian duct or infiltration from Douglas pouch

extragenital manifestation by hematogenous metastases and pluripotent cells
how is the deep ovarian endometriosis also called?
endometrioma = chocolate cyst
what are cardinal symptoms of endometriosis
dysmenorrhoea and dyspareunia

other symptoms are dysuria and dyschezia as well as chronic pain
what are typical additional examinations for diagnosis of endometriosis?
vaginal sonography
how is endometriosis ultimately diagnosed
laparascopy with or without biopsy
what are common complications of endometriosis?
sterility

and

relapse after therapy
what are the three therapeutic approaches to endometriosis?
expectative

symptomatic

endocrine medicamentous
what does symptomatic treatment of endometriosis include?
NSAID

and

ovulation inhibitors
what are the principal choices of endocrine medicamentous treatment of endometriosis?
GnRH analogues

anti-gonadotropins

gestagens
what is the principle behind endocrine medicamentous treatment of endometriosis?
estrogen deprivation
which forms of endometriosis respond poorly to endocrine therapy?
deeply infiltrating endometriosis and endometrioma
what are indications for surgical therapy of endometriosis?
advanced stages of disease

complications

for definitive treatment
what are typical indications for surgical treatment of endometriosis?
endometrioma and peritoneal endometriosis in sterility