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255 Cards in this Set

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What to ask when learning about patient's G/U problems?
Onset of problem? Effect of problem? Pain? UTI history? Hesitancy/straining? dysuria? hematuria? nocturia? incontinence? History of renal calculi? anuria? Smoker? (increases risk of renal/bladder cancer) Alcohol drinker? Fever/chills?
What are the elements of physical assessment for G/U?
inspection
auscultation
palpation
(percussion?)
Where is the area of focus when assessing for G/U problems?
abdomen
suprapubic region
genetalia
lower back
When perfoming a G/U exam, where should you inspect & what are you looking for?
abdomen & flank regions
asymmetry, swelling, discoloration (bruising/redness)
especially in costovertebral region
What are we listening for in G/U examination?
sign of bruit over each renal artery (may indicate stenosis)
(mid-clavicular line)
renal vessels best heard midway between xyphoid process & umbilicus--2cm from the midline
Can you palpate the kidneys?
Not normally, but possible if diseased--painful for patient.
What else can be detected in G/U exam?
distended bladder (may need Foley catheter to take care of that problem)
Why would you percuss the bladder?
to assess for residual urine--
sounds dull if distended
If a pt has renal calculi, percuss the ___________ flank first.
non-tender
What does costovertebral tenderness suggest?
kidney infection (pyelonephritis)
creatinine is
a protein produced by muscle and released into the blood
serum creatinine measures
muscle and protein metabolism
Why is serum creatinine an excellent measure of kidney function?
muscle mass and creatinine are usually constant--only renal disease raises creatinine levels
What can elevate BUN?
rapid cell destruction from infection, strenuous exercise (e.g. marathon), high fevers--things that cause you metabolize protein
Is BUN a reliable measurement of kidney function? Why?
No, other things besides diseased kidneys may raise BUN levels
What is Blood Urea Nitrogen (BUN)?
a byproduct of protein metabolism in the liver
Why is the BUN/creatinine ratio helpful?
Helps determine if it is a renal function problem or something else causing the elevation of BUN. With hypovolemia, BUN rises more rapidly than creatinine.
Normal creatinine levels
0.7-1.2 mg/dL
Nephrologists view anyone with a constant creatinine level of 1.2 as .....
"prerenal"
Normal BUN range
7-18 mg/dL
Normal BUN:Creatinine ratio
10:1 or 20:1
What is estimated GFR?
another good indicator of kidney function
on serum lab tests
different values for blacks & whites
What are we looking for when inspecting a urine sample?
color
odor
clarity
slight ammonia smell
specific gravity measures...
the concentration of urine compared to water (1.0)

Urine specific gravity
How does the diet affect urinary pH?
vegetables/certain fruits--alkaline
high proteins--acidic

(important for recurring UTIs and renal calculi)
If blood glucose reaches a certain threshold, it may spill over into the urine. What is the threshold?
> 220 mg/dL
What is the single most important indication of renal disease?
protein in the urine
ketones are...
products of incomplete metabolism of fatty acids; don't usually see them in the urine
Why do we not normally see protein in the urine?
proteins are larger in size, so the glomerulus does not let them seep out
What types of sediment can be found in urine?
cells, casts, crystals, bacteria
(could indicate infection)
microalbuminuria is detected by what test?
immuno assay test
Normal urine albumin levels
2-20 mg/dL for men
2.8-8 mg/dL for women

(dipstick begins to measure at 30 mg/dL, well above the normal range)
Why do a C&S (culture & sensitivity) on a urine sample?
to see what organism is growing in the urine and what antibiotic will best treat it
What does the 24 hour urine creatinine clearance test do for us?
creatinine clearance test calculates the GFR
What does GFR measure?
the volume of blood cleared of endogenous creatinine in 1 minute
What is the best indicator of overall kidney function?
24 hour urine creatinine clearance
24 hour urine creatinine clearance compares which creatinines?
blood creatinine vs. urine creatinine
Normal creatinine clearance range:
0.6 to 1.8 g per 24h
90-139 mL/min--males
80-125 mL/min--females
Creatinine clearance of <10 mL/min is...
criteria for dialysis
When should a 24 hour urine test start? What urine is collected first?
First thing in the AM when pt gets out of bed.
(FIRST voiding is not collected)
Where should urine be kept during 24 hr urine test?
on ice
Urine osmoloality measures...
total # of particles in the urine (concentration)

Normal is 300-900 milliosmoles/kg in 24 hr period
What radiographic exams are done on the urinary system?
KUB
IVP
CT
cystography
What does a KUB (kidneys, ureters, bladder x-ray) show?
gross anatomic features
any obvious stones or strictures
calcifications (stones, TB)
obstructions
shows physician shape & size of organs
What is IVP and what does it show?
intravenous pylography
A series of x-rays follows the flow of an injected dye through the urinary system.
Gives a better idea of urinary system outline and function--shows size, shape, adequacy uptake, strictures in K,U,B
Why be careful with contrast?
contrast-induced renal failure is a risk, esp. in elderly, dehydrated, and people with renal insufficiency
(must know BUN & creatinine levels before doing an IVP)
What does CT show?
a 3-D presentation of K, U, B, & surroundings
Can show renal calculi, tumors, obstructions, lacerations, & other abnormalities
(pictures done in "slices," can be done without contrast medium if necessary, but not normal)
What is a cystourethography?
An x-ray that takes pictures of the bladder while pt is voiding. Must have urinary catheter b/c dye is injected into bladder via catheter.
Done for recurrent UTIs (abnormality), injury, strictures of urethra, enlarged prostate
renal arteriography
looks for damage to the blood vessels in the kidneys
(aneurysms, ruptured vessels)
What is important when caring for a post-op renal arteriography pt?
Monitor for bleeding--puncture side, swelling/edema, peripheral pulses, warmth of extremeties
Encourage fluid intake. Keep pt prone with legs straight.
Why is a renal biopsy performed?
to determine pathologic reasons for renal function
Danger in performing renal biopsy?
Bleeding--kidneys are very vascular.
Monitor coagulation pre-op.
Monitor BP, urine (hematuria), HR
Left kidney usually biopsied (closer to skin, not next to liver)
Renal ultrasounds use sound waves to detect abnormalities in the tissues & organs. Is this the normal method of checking for kidney stones?
No, usually KUB, IVP are used--but it could be a first step in diagnosis
Upper or lower urinary tract? What is infected?
Cystitis
Prostatitis
Pyelonephritis
Urethritis
lower--urinary bladder
lower
upper
lower--urethra
What predisposes one to UTIs?
obstruction, calculi, age, gender, sexual activity, diabetes mellitus, DM, vesicouretral reflux, charicteristics of urine
How does obstruction contribute to UTIs?
causes incomplete bladder emptying, creating a medium for bacterial growth
(renal calculi, BPH-men, cystocoele/prolapse-females)
Pyelonephritis causes ____________ and can lead to ___________.
scarring; renal failure
Irritation of perineum and urethra promotes _____________ and spermicides can ___________
migration of bacteria
alter urine pH
Bladder displacement during pregnancy redisposes to ...
cystitis
Why does diabetes mellitus predispose one to UTIs?
excess glucose provides a rich medium for bacteria
How does urine pH affect UTIs?
alkaline urine promotes bacterial growth
Cystitis can be caused by...
bacteria, virusus, fungi, parasites (infectious)
chemicals, radiation (non-infectious)
Typically, an infection moves _____ the urinary tract.
up
Cystitis is not life-threatening, but infectious cystitis can lead to ________ and __________ , which are considered life-threatening.
pyelonephritis
sepsis
Spread of infection from the urinary tract to the systemic circulation is termed....
urosepsis
What can urosepsis lead to?
overwhelming organ failure, shock, death
Is urosepsis common?
Most common cause of sepsis in hospitalized pt is UTI
(incidence of UTI is 2nd only to upper respiratory infections in primary care)
Manifestations of cystitis
frequency
urgency
dysuria
hesitancy
low back pain
incontinence
nocturia
burning pain
Urine may be cloudy, have foul odor, or blood tinged
Distension after voiding (incomplete emptying--predisposes to infection)
Diagnosis of UTI
urinalysis--count bacteria, WBCs andRBCs
What urinalysis findings constitute infection?
presence of 100,000 colonies per mL
presence of WBCs
If obstruction or constriction is suspected, what screening tools may be used?
urography
abdominal sonography
computerized tomography
cystoscopy
Drug therapy for cystitis:
antibiotics (based on C&S and pt's reactions)--fluoroquinilones, cephalosporins, penicillin, sulfonamides
analgesics (for burning and pain associated with voiding)--pyridium (turns urine orange)
antispasmodics
antifungals
Interventions for cystitis
Maintaining urinary elimination --voiding on urges, develop toileting routines
Dietary--drinking 8 oz with meals & between meals, no less than 2L, cranberry juice
Warm sitz bath--ease of starting urinary flow
Surgery, if necessary
Nursing responsibilities to treat/prevent bladder infection:
Proper hydration--3L daily is optimal
Acid/ash diet--produce acidic urine--cranberry juice, meats, eggs, prunes, cranberries, plums, whole grains, vitamin C
Administer meds, analgesics on time as ordered
Wipe front to back, shower--don't bathe, cotton underwear, void before & after sex, no tight jeans, avoid feminine hygiene sprays and perfumed products
Use strict, aseptic technique when inserting catheter
What is the cause of urethritis?
males--usually STD
females--usually in post-menopausal women (low estrogen levels?)
Symptoms of urethritis
similar to UTI. Also:
high frequency, low output
pain--burning
nocturia
dark/cloudy urine
strong "fishy" smell
strong urge to urinate
dull pain in back or abdomen
general feeling of being unwell
fever?
Definition of prostratitis
inflammation of the prostate usually asssociated with urethritis and/or infection of the lower urinary tract
Common bacterial causes of prostratitis
e-coli
enterobacter
symptoms of prostratitis
low back pain
urgency
fever/chills
dysuria
urinary frequency
Tx of prostratitis
antibiotics
oral anti-inflammatory agents
prostatic massage
Sitz baths
noninfectious urinary disorders
urinary strictures
urinary incontinence
urolithiasis
bladder trauma
urothelial cancer
What are urethral strictures?
Narrowed areas of the urethra
Causes of urethral strictures
childbirth complications
catheterization trauma
compliacations of STDs
(more common in men)
Most common symptoms of urethral strictures
obstruction of urine flow
painless, but urinary stasis can lead to UTIs
urethroplasty
infected area removed or grafted to allow urinary passage
urinary incontinence
involuntary loss of urine severe enough to cause social problems
(not a normal consequence of aging/childbirth)
Is urinary incontinence commonly reported?
very underreported due to stigma
Why does urinary incontinence occur?
pressure in urethra greater than pressure in bladder
Forms of urinary incontinence
stress incontinence--can't tighten urethra enough; must strengthen weakened pelvic girdle muscles
urge incontinence--inability to suppress the urge from the detrussor muscle
overflow incontinence--failure of detrussor to respond by contracting (urine leaks out to prevent bladder rupture)
mixed incontinence-- occurs more often in females
functional incontinence--occurs with loss of cognitive function (e.g. dementia), unaware
Interventions for stress incontinence
exercises--Kegel therapy (for females)
dietary--weight loss, avoid alcohol & caffeine
drugs--estrogen (stress incont.), anticholinergics, antispasmodics, TCAs
vaginal cone--a weight used to exercise pelvic floor muscles
Also: psychotherapy, behavior modification, surgery
Interventions for urge incontinence
drug--anticholinergics
diet--avoid diuretic foods (caffeine, alcohol)
Space fluids throughout day, limit in evening
Toileting routines (regular intervals throughout day)
Bladder training; habit training
Exercises--Kegel
Electrical stimulation--stimulates muscles
Interventions for reflex incontinence
drug therapies
Behaviour interventions:
bladder compression (manually assist bladder in emptying)
Valsalva maneuver--increases pressure
Double voiding--go, stand, go again
Interventions for reflex incontinence
Adult "diapers",
Urinary catheterization
(pt doesn't realize that there is a socially acceptable place to empty bladder)
What is urolithiasis?
nephrotlithiasis?
ureterolithiasis?
presence of calculi in urinary tract
formation of calculi in kidneys
formation of calculi in ureter
What % of people form renal calculi?
10%
If bilateral obstruction occurs from calculi...
can cause acute renal failure
hydronephrosis
enlargement of kidney
irreversible, can cause permanent damage
Incidence of renal calculi is higher in ____, with the exception of _______ calculi
men, struvite
Most common type of calculus?
Calcium
Pain from renal calculi is the result of
ureteral spasm--excrutiating
Damages urothelial lining--hematuria
If obstruction is not removed
urinary stasis can lead to UTI, renal function impairment
Factors that predispose to formation of calculi:
urinary stasis
urinary retention
immobilization
dehydration
Keep pt hydrated, & bladder emptied
Struvite calculi need a(n) __________ environment to form.
alkaline
Manifestations of urolithiasis
renal colic (sudden, unbearable, pain)
N/V, pallor, diaphoresis
frequency, dysuria--when stone reaches bladder
flank pain--stone in kidney or upper ureter
flank pain + abdominal/scrotal/vulvar radiation--stone in lower ureter or bladder
Pain sharpest when stone is moving or urinary flow blocked; resolves when stone passes into bladder
Other symptoms of kidney stones (besides pain)
hematuria
rust-colored appearance
odor
oliguria
anuria (bilateral obstruction--leads to acute renal failure)
Obstruction of urine is a(n) __________; could lead to ________
emergency; loss of kidney function
Diagnostic assessment of renal calculi (besides obvious presentation)
urinalisys--RBCs from damage to endothelial lining, WBCs from inflammation/infection
KUB--stone will show on x-ray; hydronephrosis
Urogram--shows if urinary obstruction is present
Contrast dye can lead to ___________ so ____________is necessary
acute renal failure
forcing fluids (to flush out the dye)
Most important intervention to patient with kidney stones
pain relief--NSAID (ketorolac/toredol) or opioid given intravenously
Nonsurgical interventions for urolithiasis
pain relief meds
alternative therapy (visualization/relaxation)
avoid overhydration (stone may just float in the kidney)
extracorporeal shock wave lithotripsy (breaks up stones with sound waves)
Surgical interventions for urolithiasis
Minimally invasive: basket to retrieve stone from ureter
or
Open the kidney to remove large stone (struvite, e.g.)
Nursing responsibilities for kidney stone pt
Take a good history
Monitor lab results (UA, WBCs--infection?)
pain relief!
Keep pt well-hydrated
Save stones for lab if you catch any (strainer)
Dietary changes? (decrease calcium: spinach, chocolate, juices, soft drinks, berries--oxylate)
Citrates can decrease stone formation (lemonade)
Uric acid stones
caused by a LOW acidic pH
Taking a history on a renal calculi pt? Ask about:
dietary habits,
risk factors (medications),
past UTIs,
gout,
mobility status
signs of infection/obstruction--fever, chills, N/V, pain/urgency/frequency/hesitation/incontinence with urination
Uterothelial cancers
malignant tumors of the urothelium
usually occur in the bladders
can be highly invasisve (metastatic)
Greatest risk factor for bladder cancer
Smoking (4-7 times more likely)
Also other chemicals (chlorine byproducts)
Occupations at higher risk for bladder cancer:
dry cleaning, paper manufacturing, apparel manufacturing, rope/twine making
Tx for bladder cancer is dependent on...
staging
Signs of bladder cancer
painless hematuria (pt may ignore this) is predominant sign
Cystoscopy is primary means for evaluating for cancer

Also dysuria, frequency, urgency
Tx for bladder cancer
biopsy for staging
chemotherapy/radiation therapy
radical surgical removal
Systemic chemotherapy with metastases
Causes of bladder trauma
penetrations--stabbing, gunshot, fractures
blunt injury--compression of abdominal wall & bladder (e.g. seatbelt in car wreck)
Does bladder trauma require surgery?
Yes, if other than simple contusion
Cystography will show defects in bladder filling
Cystourethrogram will show bladder emptying (extravasation of urine)
How does chronic renal failure affect every body system?
Fluid volume excess
Electrolyte and acid-base
Accumulated nitrogenous wastes
Hormonal inadequacies
Definition of acute renal failure
a rapid decrease in renal function, leading to the accumulation of metabolic waste in the body
Causes of acute renal failure
Inadequate kidney perfusion
Damage to the glomeruli
Obstruction
Categories of acute renal failure
Prerenal azotemia
-Impaired or diminished renal blood flow
Intrarenal ARF
-Damage to filtering structures
Postrenal azotemia
-Obstruction in the flow of urine distal to the kidney
What is prerenal azotemia
Pt has Impaired or diminished renal blood flow
What is intrarenal Acute Renal Failure
Damage to filtering structures
What is postrenal azotemia?
Obstruction in the flow of urine distal to the kidney
Causes of prerenal azotemia:
Hemorrhage, Shock, Sepsis, Anaphylaxis, Volume depletion, Pulmonary embolism, Pericardial tamponade, Congestive heart failure
(anything that dramatically reduces blood flow to kidneys)
Manifestations of prerenal azotemia:
Hypotension
Tachycardia
Lethargy
Decreased urine output
Decreased cardiac output
Decreased central venous pressure
Characteristics of postrenal azotemia:
Bilateral obstruction must occur
Obstruction results in elevated Bowman capsule pressure
Urine production is impaired
Azotemia develops
Characteristics of intrarenal failure:
Acute tubular necrosis (ATN)
Accounts for 20-30% of ARF cases
Nephron injury occurs
Renal tubule - most common site of injury
Recovery - minimum of 2 weeks
Normal renal function may take 3-12 months
Manifestations of intrarenal failure:
Oliguria or anuria
Edema/rales/crackles
Hypertension
Tachycardia
Shortness of breath
Jugular distention
Elevated CVP
Phases of ARF
Initiation Period
Oliguria Period
Diuresis Period
Recovery Period
Characteristics of Oliguric phase (in ARF):
Increasing BUN & Creatinine
Hyperkalemia
Metabolic acidosis
Hyperphosphatemia
Hypocalcemia
Hypermagnesemia
Diagnostic Assessment in ARF
↑BUN
↑Creatinine
Abnormalities in serum electrolytes
Urine specific gravity >1.020 (prerenal) & 1.010 in intrarenal failure
X-ray to determine kidney size
Renal ultrasound, CT, Renal biopsy
Interventions in ARF
Drug therapy
+Diuretics
+Fluid challenges
+Calcium Channel Blockers
+sodium polystyrene (Kayexalate)
Diet therapy
Dialysis Therapy
Continuous renal replacement therapy
Nutritional Therapy for ARF
High carbohydrate meals
Restrict potassium and phosphorus
Prevent dehydration and overhydration
Indications for dialysis in ARF
Uremia
Uremic pericarditis
Persistent hyperkalemia
Uremic encephalopathy
Uncompensated metabolic acidosis
Fluid volume excess unresponsive to diuretics
NAME THAT CONDITION:
Progressive, irreversible kidney injury
Terminates in ESRD
Mortality is 100% without dialysis or renal transplant
Treatments are based on underlying cause
Chronic Renal Failure
In Chronic Renal Failure, Healthy nephrons compensate by _____________________.
enlarging and increasing clearance capacity
CRF Stages 1 & 2: _______________ Renal Reserve
Renal function decrease ________
No accumulation of ____________
Healthy kidney compensates
↓ ability to ____________ urine
Diminished
50%
metabolic wastes
concentrate
CRF Stage 3: Renal ____________
Renal function ↓_______
Metabolic wastes begin ______________
Affected nephrons no longer compensate
↑Creatinine & ↑BUN are evidence of ↓GFR & ↓Creatinine clearance
Urinary output indicates impairment of filtrate _________________ ability
Insufficiency
75%
accumulating
concentration
CRF Stages 4 & 5: _______________
Renal function ↓ _______
Excessive amounts of _______________
Hypocalcemia worsens
Erythropoietin levels are extremely ___________
↑K+ levels & metabolic ____________ may be life threatening
End-stage renal disease
90%
nitrogenous wastes
depressed
acidosis
Manifestations of ESRD
Fluid volume overload
Jugular vein distention
Bounding pulses
Rales in the lungs
Peripheral edema
Hypertension/Chest pain
Osteodystrophy
Anemia
WHAT METABOLIC IMBALANCE AM I?
Anorexia
Tachycardia
Nausea & Vomiting
Hyperphosphatemia
WHAT METABOLIC IMBALANCE AM I?
Seizures
Numbness
Carpopedal spasms
Hypocalcemia
WHAT METABOLIC IMBALANCE AM I?
Irritability
Bradycardia
Dysrhythmias
Elevated T wave on EKG
Hyperkalemia
Drug therapy for ESRD includes:
Diuretics
Erythropoietin
Antihypertensives
Phosphate binders
Calcimimetic Agents
Vitamin D supplement
Vitamin B complex vitamins
Name 3 renal replacement therapies.
Hemodialysis
Peritoneal Dialysis
Renal Transplant
What 3 physical principles are used in dialysis?
Osmosis
Ultrafiltration
Diffusion
Water moves by concentration gradient in....
osmosis
Solution moves by pressure gradient in....
ultrafiltration
Solvent moves by concentration gradient in....
diffusion
____________ is the most common form of dialysis. It also provides the most ________ correction of abnormalities.
hemodialysis
rapid
Hemodialysis uses a _____________ membrane is between the blood and ___________
Dialysate is pumped past the membrane in the _______________ blood flow
Requires direct access to the patient’s ____________ via special intravenous catheters or vascular access
semipermeable
dialysate
opposite direction of
bloodstream
Primary complications of hemodialysis
Hypotension
Dysrhythmias
Muscle cramps
Hypovolemic shock
Orthostatic hypotension
Nutrition for hemodialysis patient
Increased protein
Fluid restriction
Sodium restriction
Potassium restriction
Phosphorus restriction
Alternative to hemodialysis
Takes place within the peritoneal cavity
Slower process for waste removal
Semipermeable membrane in this process is the peritoneal membrane
peritoneal dialysis
Types of peritoneal dialysis:
CAPD
CCPD
IPD
Continuous ambulatory peritoneal dialysis
Continuous cyclic peritoneal dialysis
Intermittent peritoneal dialysis
Advantages of peritoneal dialysis:
Self-management
Less restrictive diet
Freedom from a machine
Control over daily activities
Avoidance of venipuncture
Less restriction of fluid intake
Less risk of blood pressure problems
Diet for peritoneal dialysis
High-protein, well balanced diet
Increase daily fiber intake
Limit carbohydrates in weight gain
Potassium, sodium, and fluid restrictions not usually needed
Renal Transplant:
Alternative to _____________ in ESRD
Primary limiting condition is ____________ of organs
Refinements in ________ therapy and surgical _____________ have made transplantation a viable option
Success is ____________ any other organ transplantation
dialysis
availability
immunosuppressive; techniques
superior to
In kidney transplants, what outcome improves prognosis?
What does organ survival depend upon?
What kind of medication will be necessary?
Immediate functioning of organ
blocking recipient's immune response to transplanted organ
anti-rejection medication
Immunosuppressive therapy for transplant recipients includes ________________.
Prednisone (a Corticosteroid)
manifestations of organ rejection
Oliguria
Edema
Fever
Weight gain
Increasing blood pressure
Swelling or tenderness
Manifestations of infection following a kidney transplant:
Shaking
Fever/chills
Tachypnea
Tachycardia
Increase/decrease in WBCs indicating leukocytosis or leukopenia
Polycystic kidney disease:
___________ is the most common form (30s-40s onset)
In ____________ the symptoms begin in the earliest months of life
Acquired cystic kidney disease develops as a result of ____________
Autosomal dominant PKD
Autosomal recessive PKD
long term kidney problems (kidney failure/dialysis)
PKD, one of the most common kidney disorders, is more common in what race?
Caucasians
What happens in PKD?
Fluid filled cysts form in the nephron, causing kidneys to become grossly enlarged and displace other organs. The cysts are prone to infection and rupture.
Is PKD painful?
Yes, as the kidneys enlarge, it becomes quite painful.
PKD manifestations
pain in the back/side
renal calculi
headaches
UTIs
hematuria
cysts in kidneys and other organs
heart valve abnormalities
Vascular cysts from PKD are called ______ cysts and may rupture in the ___________
berry; brain
Can you palpate the kidneys in PKD?
You can due to their enormous size, but you should take care not to rupture a cyst
How do we diagnose PKD?
urinalysis (protein, blood, bacteria, WBCs)
renal sonograms
CT scans
MRIs
Tx for PKD
control BP & other comorbidities
medicine & surgery for pain
treat/avoid infection (antibiotics)
will lead to ESRD, necessitating dialysis or transplant
No cure!
Name 3 obstructive disorders:
Hydronephrosis
Hydroureter
Urethral Strictures
Describe hydronephrosis.
an abnormal collection of urine in the renal pelvis; usually indicates an obstruction high in the ureter
Describe hydroureter.
obstruction of the lower part of the ureter (calculus, scar tissue, kink in the ureter, tumor)
permanent damage can occur of o
Describe urethral strictures.
scars in or around the urethra (from surgery, disease, or injury
external pressure (rare)
Increased Risk for Urethral strictures
Men with repeated STDs, urethritis, BPH
injury or trauma to pelvic region
(even catheter induction)
Pyelonephritis
a kidney infection (usu. bacterial) that has spread from the bladder (from a catheter, cystoscope, surgery, conditions such as kidney stones that prevent outflow from the bladder)
What is the hallmark sign of pyelonephritis?
costovertebral angle tenderness
Why will the acutely ill patient with pyelonephritis need IV antibiotics?
Due to risk of bacturemia
Using your fist to rap the back at the costovertebral angle will result in ...
severe pain for the pt with pyelonephritis
Chronic pyelonephritis is characterized by:
renal inflammation & fibrosis (from recurrent infections, vesicoureteral reflux)
most common in pts with anatomical anomaly
long term complications: hypertension, renal failure, proteinuria, glomerulosclerosis
Manifestations of chronic pyelonephritis
fatigue, fever, flank pain, dysuria, N/V,
Interventions for chronic pyelonephritis
ID & treat infections promptly
Monitor & control BP
If renal impairment is present, increase fluid intake to prevent dehydration
Dietary consult (protein restrictions?)
Surgery (if predisposed to pyelonephritis)
Name 3 immunologic renal disorders.
Acute Glomerulonepritis
Chronic Glomerulonepritis
Nephrotic Syndrome
What is glomerulonephritis?
a renal disease usually affecting both kidneys
inflammation of the glomeruli
treatment depends on the pattern of infection
Acute glomerulonephritis is an immunologic triggered inflammation of glomerular tissue. Can damage kidneys.
What is the prototype?
post-streptococcal glomerulonephritis
What happens in glomerulonephritis?
Infection causes glomeruli to swell & narrow. Protein & RBCs are allowed to exit the bloodstream & enter the urine.
What is azotemia?
Retention of excessive amounts of nitrogenous wastes in the blood.
Manifestations of glomerulonephritis:
hematuria, proteinuria (albumin), azotemia, hypertension (retention of renal sodium & water), edema in face & eyelids, assess for crackles, dyspnea/orthopnea, weight (fluid retention), fatigue, N/V if uremia is present
Lab values for glomerulonephritis
hematuria, proteinuria
decreased serum protein b/c protein is lost in urine
fluid retention
GFR is decreased
percutaneous renal biopsy is done
Treatment for glomerulonephritis
abx, diuretics, sodium/water restrictions, antihypertensive therapy, protein/potassium restrictions (prevent hyperkalemia), short term hemodialysis
diuresis usually occurs in days to weeks & GFR normalizes
Chronic glomerulonephritis
irreversible & progressive glomerular & tubular interstitial fibrosis, resulting in a decreased GFR & accumulation of metabolic wastes
Can lead to CKD, ESRD & CVD,
End result is HTN, small kidneys, and renal failure
What symptoms are often the only ones identified in chronic glomerulonephritis?
Mild proteinuria, hematuria, HTN, and occasional edema
Name some manifestations of chronic glomerulonephritis.
nocturia, HTN, edema, signs of uremia (weakness, fatigue, loss of appetite, pruritis, tremors, seizures)
The following assessment findings indicate _______________:

+hyperkalemia**, metabolic acidosis, hypocalcemia**, hyperphospatemia**, anemia**, hypoalbuminemia, mental status changes, impaired nerve conduction
+Albumin lost in urine, reduced GFR
+Elevated BUN (norm is 7-18 mg/dL), anemia, increased serum creatinine (norm is 0.6-1.2 mg/dL)
glomerulonephritis
What is nephrotic syndrome?
a condition of increased glomerular permeability causing massive proteinuria, edema, and hypoalbuminemia
The bridge between CKD and ESRD
Hypoalbuminemia leads to increased liver activity--lipid production, hypercoaguability, leads to proteinuria & further decline in kidney function
Proteinuria causes
Primary features of nephrotic syndrome:
proteinuria: > 3.5 g of protein in 24 h
hypoabuminemia: < 3g/dL of serum albumin
edema
lipiduria
HTN
Increased coagulation
Complications seen in nephrotic syndrome
infection, thromboembolism, pulmonary emboli (from increased coagulation, acute, renal failure, and accelerated atherosclerosis)
Medical mgmt of nephrotic syndrome
diuretics, ACE inhibitors (to reduce proteinuria)
cyclosporin, corticosteroids, antineoplastic agents, immunosuppressants (to control immune response)
Nursing Responsibilities for pt with nephrotic syndrome
Teaching diet therapy
Moderating protein (1 g protein/kg/day)
Restricting sodium, potassium
Vitamin replacement (calcium, Vit D)
Encourage flu shot
Teach to prevent infection
Monitor I & O, weight, edema, electrolytes, signs of Pulmonary edema
Ensure quality diet, adequate intake
nephrosclerosis is...
a progressive disease resulting in hardening of small blood vessels in kidneys
Nephrosclerosis is usually the result of
HTN or diabetes
2nd most common cause of ESRD in Caucasians (1st common cause in blacks)
nephrosclerosis
Treatment of nephrosclerosis aims at...
reduction of BP (to preserve renal function)
What is renovascular disease?
a pathologic process affecting renal arteries, resulting in severe lumen narrowing & drastic reduction of bloodflow to kidneys
causing ischemia
Most common causes of renovascular disease?
renal artery stenosis from atherosclerosis or fibromuscular hyperplasia
Leading cause of ESRD?
diabetic nephropathy
In diabetic nephropathy, we must control
protein intake, BP
Can dipstick in urine detect protein in urine in diabetic nephropathy?
Not until after progressive damage has already occurred
What constitutes major renal trauma?
Damage (lacerations) to the cortex, medulla, or renal vessels
Involves bleeding; Requires surgery
How do we detect extravasation of urine following kidney, ureter, or bladder injury?
X-ray with contrast dye, CAT scan
What does prostrate specific antigen show?
Detects local progression and early recurrence of CA
PSA >10ng/mL indicates high probability of prostate cancer (norm is 4 ng/mL)
What is acid phosphatase level used for?
helps diagnose and stage prostatic cancer
Normal 0.11-0.60U/L
What is the most important screening tool for prostate cancer?
digital rectal exam
size, shape & constistency of prostate are examined
What organism causes prostatitis?
Most commonly, E. coli.
Prostitis is often associated with lower urinary tract symptoms and ______ discomfort or dysfunction
sexual
Most common urologic diagnosis in men younger than 50
prostitis
Manifestations of prostitis
Urgency
Burning
Nocturia
Frequency
Perineal discomfort
Pain with/without ejaculation
Managing prostitis
Antibiotics for 10-14 days
Analgesics for pain
Bedrest helps alleviate symptoms
Sitz baths for pain and spasm relief
Stool softeners to prevent straining
Avoid sitting for long periods of time
Definition of Benign Prostatic Hyperplasia
enlargement or hypertrophy of the prostate gland
One of the most common pathologic conditions in the aging male
Second most common cause of surgical intervention in males over age 60
BPH
WHAT IS THIS CONDITION?
Nocturia
Urinary frequency
Dribbling at the end of urination
Hesitancy starting urine flow
Abdominal straining with urination
Low excretion volume
Recurrent urinary tract infection
Increased frequency at night
Benign Prostatic Hyperplasia
Medications for BPH
Medications
5-alpha reductase inhibitor
finesteride (Proscar)
Alpha-adrenergic receptor blockers
Cardura
Hytrin
Most common cancer in men
Second leading cause of cancer death
Prostate cancer
Most prostate cancers are what specific type of cancer?
adenocarcinomas
What is removed during a radical prostatectomy?
prostate and seminal vesicles
What are the negative consequences of radical prostatectomy?
Impotence
Various degrees of urinary incontinence
Defn of erectile dysfunction (ED)
inability to achieve or maintain an erection for sexual intercourse
Tx of ED
Lifestyle changes
Psychotherapy
Prostheses
Medication therapy
Phosphodiesterase inhibitors
Viagra
Levitra
Cialis
Testerone
What is testicular torsion?
Rotation of the testis which twist the blood vessels in the spermatic cord
It is a Medical emergency
Symptoms of testicular torsion:
sudden testicular pain, nausea, lightheadedness, swelling of the scrotum
Most common cancer in males ages 15-35
Second most common malignancy in males aged 35-39
testicular cancer
Testicular cancer is usually ____________ and ___________ early, spreading to the __________ and the __________
malignant; metastasizes; lymph nodes; lungs
Testicular cancer is one of the most __________ solid tumors and is __________ bilateral
curable; rarely
MANIFESTATIONS OF testicular cancer:
Lump or swelling, Discomfort, pain, or feeling of heaviness in a ___________
Pain or dull ache in the____________ or lower ________
Enlargement of a _________, or change in the way it feels
Sudden collection of fluid in the __________
Enlargement or tenderness of the ___________
testicle
back; abdomen
testicle
scrotum
breasts
Tx of testicular cancer:
Surgery (Orchiectomy)
Chemotherapy
Radiation therapy
What is a Spermatocele?
a sperm-containing cystic mass that develops on the epididymis alongside the testicle
What is a Varicocele?
a cluster of dilated veins posterior to and above the testes
What is a Hydrocele?
a cystic mass, usually filled with straw-colored fluid, forming around the testis
What is Cryptorchidism?
failure of the testes to descend into the scrotum
What is Hypospadias?
a congenital anomalie in which the urethral opening is a groove on the underside of the penis
What is Epispadias?
a congenital anomaly in which the urethral opening is on the dorsum of the penis
Why is a breast self exam best performed after menstrual cycle begins?
(During days 5 to 7 counting the first day of the cycle as 1)
Less fluid is retained at this time--easier to palpate a mass
dialyzer
dialysis machine ("artificial kidney")--contains a semipermeable membrane through which only particles of a certain size can pass
urinary casts
proteins secreted by damaged kidney tubules
exchange (peritoneal dialysis)
complete cycle of peritoneal dialysis; includes fill, dwell, and drain phases
Protection of ___________ is a high priority for chronic hemodialysis patients
the permanent dialysis access (fistula or graft)
What is the most common and serious complication of peritoneal dialysis?
peritonitis
What is a suprapubic catheter?
a urinary catheter that is inserted through a suprapubic incision into the bladder