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22 Cards in this Set
- Front
- Back
What hormone promotes glycogenesis
What is the enzymatic Pathway? |
Insulin
Glycogen synthetase |
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What Hormones promote glycogenolysis?
What is the enzymatic pathway? |
Epi and Glucagon
Glycogen Phosphorylase |
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What hormone promotes glucose breakdown?
What is the enzymatic pathway? |
Insulin
Phosphofructose Kinase to turn F-6-Ph into Fructose-1,6-diphosphate. |
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What hormone promotes glucose release?
What is the enzymatic pathway? |
Epi and Glucagon
Glucose-6-phosphatase |
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What hormone promotes FA breakdown for ketogenesis?
What is the enzymatic pathway? |
Glucagon
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Only site of glucose-6-phosphatase synthesis.
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Liver
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Location of Satiety Center
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PVN
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Location of Appetite center
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Lateral Hypothalamus (LHA)
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What does "Orexis" mean?
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Appetite
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Role of NPY
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stimulate appetite via orexins
suppress satiety via inhibition of CRH |
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Role of Melanocortins
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Stimulate Satiety via CRH
Supress appetite via inhibition of Orexins |
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Factors that decrease Short term Food Intake
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CCK, Insulin, Gastric distention, Glucose use.
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Factors that decrease Long term Food Intake
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Leptin
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Environmental or Psychological Factors influencing Food Intake
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Stress, Anxiety, Boredom, Depression, Desirability of food, and Amount of food.
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Factors affecting appetite before full disgestion.
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Full stomach- PYY
Empty stomach- Ghrelin |
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What is Leptin?
What is it's role in metabolism? |
Cytokine/Hormone secreted by adipose tissues that act on the Arcuate nucleus.
Decreases appetite and minorly increases metabolic rate. |
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Symptoms of Diabetes Mellitus
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Hyperkalemia, Hypotension, Hyperglycemia, high FA and AA in plasma, Polyurea, Dehydration, increased respiration
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Insulin effect on K+
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Increases K+ uptake into cells
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Cause of Type I diabetes mellitus
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Autoimmune destruction of B-cells in pancreas.
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Cause of Type II diabetes mellitus
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Insulin Resistance.
(downregulation of glucose and insulin receptors) Obesity |
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Diabetes Mellitus and Metabolic Acidosis
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Results from overproduction of ketoacids and results in increased ventilation.
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Growth Metabolism
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GH and IGF aim to inc. plasma glucose by decreasing Glucose uptake.
and increase protein synthesis. |