Growing Up

Front 1

what do growth charts measure

Back 1

height
weight
head circumference

Front 2

definition of short stature

Back 2

2 SD below the mean

Front 3

how to measure upper to lower body segment ratios

Back 3

lower: symphysis to floor
upper: height - lower

Front 4

how to measure bone age

Back 4

AP x ray of left hand

Front 5

bone age is closely linked to what

Back 5

sexual maturity

Front 6

most common cause of short children

Back 6

short parents

Front 7

short stature
pubertal growth spurts are normal
bone age = chronological age

Back 7

familial short stature

Front 8

bone age is delayed 2-4 years

Back 8

constitutional growth delay

Front 9

considered late bloomers

Back 9

constitutional growth delay

Front 10

usually have mom with late menarche or dad with late final adult height

Back 10

constitutional growth delay

Front 11

what accounts for the pulsatile secretion of GH

Back 11

alternating secretion of GHRH and somatostatin

Front 12

when is the pulsatile secretion of GH most likely to occur

Back 12

stage III and IV (non-REM) sleep

Front 13

GH pulses are increased by the secretion of what

Back 13

androgens

Front 14

factors that inhibit GH release

Back 14

hyperglycemia
hypothyroidism
glucocorticoids

Front 15

factors that stimulate GH release

Back 15

sleep
exercise
stress
puberty
fasting

Front 16

lab values that suggest GH deficiency

Back 16

IGF-1 and IGFBP-3 (GH has short half life so can't check)

Front 17

short stature
poor linear growth (falls off line)
delayed bone age

Back 17

growth hormone deficiency

Front 18

test for growth hormone deficiency

Back 18

stimulation test

Front 19

GH tx is approved for what conditions

Back 19

GH deficiency
chronic renal insufficiency
Turner syndrome

Front 20

side effects of GH therapy

Back 20

increased development of malignancies

Front 21

hypersecretion of GH prepuberty causes what

Back 21

gigantism

Front 22

hypersecretion of GH postpuberty causes what

Back 22

acromegaly

Front 23

primary growth disorders

Back 23

osteochondrodysplasia
chromosomal abnormalities
intrauterine growth failure

Front 24

bone age in primary growth disorders

Back 24

delayed or equal to chronologic

Front 25

most common non-lethal chondrodysplasia

Back 25

achondroplasia

Front 26

inheritance of achondroplasia

Back 26

AD

Front 27

results from FGFR3 mutation (fibroblast growth factor receptor)

Back 27

achondroplasia

Front 28

results from functional loss of cartilage synthesis

Back 28

diastrophic dysplasia

Front 29

short adolescent female
amenorrhea

Back 29

turner syndrome

Front 30

test for any females with amenorrhea

Back 30

karyotype for Turners

Front 31

physical sx of Turners

Back 31

webbed neck
increased carrying angle
peripheral edema
short

Front 32

endocrine secondary growth disorders

Back 32

hypothyroidism
acquired GH axis disruption
cushing syndrome

Front 33

below normal linear growth rate
increased weight gain
delayed bone age

Back 33

hypothyroidism

Front 34

bone age of cushing disease

Back 34

delayed

Front 35

bone age of hypothyroidism

Back 35

delayed

Front 36

transient pituitary hormone deficiencies

Back 36

psychosocial dwarfism

Front 37

following removal from environment hormone levels normalize

Back 37

psychosocial dwarfism

Front 38

key to dx Turners syndrome

Back 38

short stature

Front 39

main complications of diastrophic dysplasia

Back 39

orthopedic disorders

Front 40

mosaic form of turner syndrome doesn't present until when

Back 40

puberty

Front 41

tx for Turners syndrome

Back 41

GH

Front 42

tumor that causes GH deficiency

Back 42

craniopharygioma