Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
20 Cards in this Set
- Front
- Back
|
A process whereby epithelial cells, as a consequence of loss of connections (desmosomes) between them, separate from one another, becoming round and eventually dying, the process ending in formation of either a cleft or a blister
|
ACANTHOLYSIS
|
|
|
An increase in thickness of the epidermis consequent to an increase in thickness of the spinous zone secondary usually to an increase in number of cells, but, episodically, to an increase in size of cells or both of them concurrently. Seen in psoriasis, lichen planus, lichen simplex chronicus.
|
ACANTHOSIS
|
|
|
Reduction in amount of tissue is a result of there being fewer cells and/or smaller cells. Atrophy can affect the epidermis, the dermis, and the subcutaneous tissue, and the skin and subcutaneous fat together
|
ATROPHY
|
|
|
"Intracellular edema" of epidermis, recognizable morphologically as swollen pale cytoplasm of affected spinous cells. Usually seen in viral infections, ie. herpes
|
BALLOONING
|
|
|
A space that does not contain fluid.
|
CLEFT
|
|
|
A dilated infundibulum stuffed by cornified cells, sebaceous secretion, and microorganisms.
|
COMEDO
|
|
|
A collection of histiocytes
|
Granuloma
|
|
|
Increased thickness of the granular zone. As a consequence of an increased number of keratocytes whose cytoplasm contains keratohyaline granules
|
HYPERGRANULOSIS
|
|
|
Hypergranulosis is a finding stereotypical for ______ ______, in which the granular zone tends to assume a wedge shape.
|
Hypergranulosis is a finding stereotypical for lichen planus, in which the granular zone tends to assume a wedge shape.
|
|
|
A thickened cornified layer of an epithelium
|
HYPERKERATOSIS
|
|
|
Hyperkeratosis may be classified as either _____keratosis, in which no nuclei are visible in cornified cells, or ____keratosis in which nuclei are retained by cornified cells.
|
Hyperkeratosis may be classified as either orthokeratosis, in which no nuclei are visible in cornified cells, or parakeratosis in which nuclei are retained by cornified cells.
|
|
|
Thickening of the skin secondary to rubbing forcefully for many months or years. The condition is typified clinically by accentuation of normal skin markings, hyperpigmentation, and induration of variable extent. Classically seen in lichen simplex chronicus.
|
LICHENIFICATION
|
|
|
"Intercellular edema" of the epidermis, expressed morphologically by widened spaces between spinous cells and by intercellular bridges that stretch across those extended spaces in company with a sprinkling of cells.
|
SPONGIOSIS
|
|
|
Some spongiotic inflammatory processes may eventuate in vesicles clinically, such as allergic _______ dermatitis.
|
Some spongiotic inflammatory processes may eventuate in vesicles clinically, such as allergic contact dermatitis.
|
|
|
Formation and exudation of pus, which consists of neutrophils and debris, that results from necrosis and degeneration consequent to the effects of destructive enzymes released from polymorphonuclear leukocytes.
|
SUPPURATION
|
|
|
Tiny spaces on either side of a basement membrane situated at the dermoepidermal junction.
|
VACUOLAR ALTERATION
|
|
|
elongation of rete ridges
|
Acanthosis
|
|
|
accumulation of fluid between keratinocytes, sometimes progressing to vesicle formation
|
SPONGIOSIS
|
|
|
Wedge-shaped hypergranulosis (correspond to Wickham’s striae)
Irregular acanthosis, saw-toothing of rete ridges Damage to the basal layer (vacuolar degeneration) Band-like dermal lymphocytic infiltrate close to the epidermis Necrotic keratinocytes in dermis=colloid or Civatte bodies |
Lichen Planus
|
|
|
Prototype for chronic dermatitis
Lichenification- accentuation of skin lines Acanthosis with irregular elongation of rete ridges Hypergranulosis, broadening of dermal papillae |
Lichen Simplex Chronicus
|
