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19 Cards in this Set
- Front
- Back
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3 disorders of the sebaceous and apocrine glands
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Acne
Rosacea Hidradenitis Suppurativa |
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Acne is a multifactorial inflammatory disease affecting _______________ follicles
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Acne is a multifactorial inflammatory disease affecting pilosebaceous follicles
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_____________ is the primary acne lesion
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Microcomedo is the primary acne lesion
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4 major factors have been identified for
Acne Vulgaris: Pathogenesis |
Abnormal desquamation of follicular keratinocytes
Sebum production Proliferation of Propionibacterium acnes Inflammation and immune response |
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4 steps of comedone formation
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1. Keratinocytes
proliferate and stick together 2. Sebum production 3. Bacteria multiply and colonize follicle 4. PMNs migrate to site as part of inflammatory response |
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Blackhead =
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open comedone
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Whitehead =
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closed comedone
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Large solid lesions that are lodged deep within the skin
May be very painful, and result in scarring |
nodules
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Sac-like lesions containing pus
Progressed from unresolved pustules Often painful and result in scarring |
cysts
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Gradations of acne severity
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Mild
Moderate Severe Noduloscystic |
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Gender predominace of rosacea
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More women than men
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Gender predominance of tissue hyperplasia related to rosacea
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Men more likely to have tissue hyperplasia
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Primary features of rosacea
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Flushing (transient erythema)
Non-transient erythema Papules and pustules Telangiectasia |
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Secondary features of rosacea
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Burning or stinging
Dry appearance Ocular manifestations Non-facial location Phymatous changes |
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Subtypes of Rosacea
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Vascular
Papulopustular Sebaceous Hyperplasia Ocular |
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Does keratization play a role in rosacea?
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no
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Aggravating Factors of Rosacea
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Sunlight
Humidity Heat Strong Winds Cold Weather Alcohol Medications Stress Hot Beverages Hot Foods Spicy Foods |
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A chronic, suppurative, scarring disease of the apocrine gland-bearing skin of the axillae, breasts and anogenital regions
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Hidradenitis Suppuritiva
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Associations of Hidradenitis Suppuritiva
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Often associated with severe cystic acne
Starts with puberty or later Abscesses often associated with sinus tracts and hypertrophic or keloidal scarring |
