Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
15 Cards in this Set
- Front
- Back
What are the features of Neisseria?
|
Gram Negative, Diplococci with flattened sides
Oxidase Positve |
|
What are the DISTInguishing features of Niesseria Meningitis?
|
GRAM NEG.
KIDNEY BEAN SHAPed Dipplococci Large Capsule: Latex Aggutination; ID N. mengitidis capsular antigens in CSF. GROWN ON CHOColate agar in 5% CO2 atmosphere and FERMENTS MALTOSE (N. Gon Deos NOT) |
|
What is the Oxidase test?
|
Oxidase Test
1.) Flood the colony with phenylenediamine in the presence of oxidase, 2.) phenylenediamine turns Black THE MAJOR OXIDASE NEGATIVE GRAM NEGATIVES are ENterobacteriacae |
|
What are the Virulance factors of Neisseria Meningitidis?
|
Capsule: Antiphagocytitic
IgA protease: Allows oropharynx colonization. Endotoxin: LPS: Fever: Overproduction of outer membrane, |
|
Defeciency in what complements predispose u to N. Meningitidis infection?
|
C5-C8
|
|
What are the disease N. Meninigitidis cause?
|
Meningitis and Meningococcocemia
ABRUPT ONSET FEVER, CHILLS, MALAISE, Prostration and a PEtechial rash.. Waterhouse Freidrichson: Fulminant Meningitis: Eccymosis, DIC, Shock, COMA, and Death. |
|
What is the treatment of N. Meningitidis?
|
Ampicillin and cefotaxime: Neonates and infants
Older: CEFOTAXime and Ceftriaxone Prophylaxis: RIfampin |
|
Neisseria Gonorrhea: Features
|
Gram Neg. Kidney bean shaped diplococci
|
|
What is the Path of N. GoN
|
Pilli: Helps with attatchment to mucosal surfaces and inhbits phagocytic uptake.
Antigenic Variation OMP-1: Used in serotyping IGA Protease: Colonization |
|
What dz. caused by N. Gon?
|
Urethritis: Male
Endocervicitis: Female: PID Infants: OPTHALMIA: Blind if untreated |
|
How is N. Gonorrhea Diag?
|
Intracellular GRAM NEG diplocci in PMN
Culture on THAYER-MARtin: OXIDASE POSITIVE: NON MALTOSE fermenter NO capsule. |
|
What is the TX of N. GOn
|
Ceftriaxone wtith Doxycycline of chlymidia suspected.
|
|
How do you prevent N. Gon in neonates
|
Erythromycin or silver nitrate in newborn eyes.
|
|
What are the features of Moraxella Catarrhalis
|
It is a Gram Neg. Diplococcus..Normal oral flora
|
|
What disease does Moraxella cause
|
Otitis media, sinusitis..
|