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15 Cards in this Set

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What are the features of Neisseria?
Gram Negative, Diplococci with flattened sides
Oxidase Positve
What are the DISTInguishing features of Niesseria Meningitis?
GRAM NEG.
KIDNEY BEAN SHAPed
Dipplococci
Large Capsule: Latex Aggutination; ID N. mengitidis capsular antigens in CSF.
GROWN ON CHOColate agar in 5% CO2 atmosphere and FERMENTS MALTOSE (N. Gon Deos NOT)
What is the Oxidase test?
Oxidase Test
1.) Flood the colony with phenylenediamine in the presence of oxidase,
2.) phenylenediamine turns Black

THE MAJOR OXIDASE NEGATIVE GRAM NEGATIVES are ENterobacteriacae
What are the Virulance factors of Neisseria Meningitidis?
Capsule: Antiphagocytitic
IgA protease: Allows oropharynx colonization.
Endotoxin: LPS: Fever: Overproduction of outer membrane,
Defeciency in what complements predispose u to N. Meningitidis infection?
C5-C8
What are the disease N. Meninigitidis cause?
Meningitis and Meningococcocemia
ABRUPT ONSET FEVER, CHILLS, MALAISE, Prostration and a PEtechial rash..
Waterhouse Freidrichson: Fulminant Meningitis: Eccymosis, DIC, Shock, COMA, and Death.
What is the treatment of N. Meningitidis?
Ampicillin and cefotaxime: Neonates and infants

Older: CEFOTAXime and Ceftriaxone
Prophylaxis: RIfampin
Neisseria Gonorrhea: Features
Gram Neg. Kidney bean shaped diplococci
What is the Path of N. GoN
Pilli: Helps with attatchment to mucosal surfaces and inhbits phagocytic uptake.
Antigenic Variation
OMP-1: Used in serotyping
IGA Protease: Colonization
What dz. caused by N. Gon?
Urethritis: Male
Endocervicitis: Female: PID
Infants: OPTHALMIA: Blind if untreated
How is N. Gonorrhea Diag?
Intracellular GRAM NEG diplocci in PMN
Culture on THAYER-MARtin: OXIDASE POSITIVE:
NON MALTOSE fermenter
NO capsule.
What is the TX of N. GOn
Ceftriaxone wtith Doxycycline of chlymidia suspected.
How do you prevent N. Gon in neonates
Erythromycin or silver nitrate in newborn eyes.
What are the features of Moraxella Catarrhalis
It is a Gram Neg. Diplococcus..Normal oral flora
What disease does Moraxella cause
Otitis media, sinusitis..