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6 Cards in this Set
- Front
- Back
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what is the dose of Indocin for acute gout attack?
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50 mg PO q8h for 3-4 days, then gradually taper off over 1-2 weeks
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what is dose of colchicine for acute gout attack?
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0.6 mg PO q 1 h until relief of side-effects occur (diarrhea) or 6 mg is reached
Ae: diarrhea and hair loss |
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2 agents of uricosuric. to promote excretion of uric acid
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1. probenecid
2. sulfinpyrazone |
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Benemid
- not effective in patients with CrCl < 50 ml/min, or - who excrete > 1000 mg of uric acid/day (maybe over produer) |
Probenecid
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Uloric
1. not the same as Allopurinol 2. dose 3. Metabolized in ? 4. check? |
1. no rash
2. 40 mg, 80 mg, 3. Liver 4. LFT |
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Allopurinol
1) MOA? 2) Max dose? 3) Renal adjustment? 4) AE 5) DDI |
1. Xanthine oxidase inhibitor
2. 800 mg/day 3. yes 4. rash 5. reduced the levels of azathioprine, 6-MP - |
