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5 Cards in this Set
- Front
- Back
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colchicine
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1. block PMN eat urate
2. not analgesic, not alter urate blood levels 3. prophylaxis |
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allopurinol
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1. must symptomatic
2. inhibit xanthine oxidase 3. preg category C 4. D/c if rash - SJS 5. c/i with 6 mercaptopurin (met by xanthin oxidase) |
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febuxostat
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1. inhibit xanthine oxidase
2. less SA and better renal dz |
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PEG-uricase
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1. metabolizes uric acid
2. use Tx-resistant gout 3. resolve tophi 4. IV |
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probenacid
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1. decrease tubule reabsorption
2. contraindicated if urine uric acid high or methotrexate 3. less effective in elderly or with aspirin 4. nephrolithiasis 5. slows penicillen excretion |
