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17 Cards in this Set

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  • Back
Naproxen
NSAID: COX-2 Inhibitor. prevents urate crystal phagocytosis.
Indomethacin
NSAID: COX-2 Inhibitor. prevents urate crystal phagocytosis.
Sulindac
NSAID: COX-2 Inhibitor. prevents urate crystal phagocytosis.
Oxaprozin
NSAID: COX-2 Inhibitor. prevents urate crystal phagocytosis.
Aspirin
COX Inhibitor - not recommended for acute gout
Tolmetin
Not understood. doesn't work for acute gout.
methylprednisone
glucocorticoid: stimulates mRNA to synthesize specific proteins and enzymes
triamcinolone
glucocorticoid: stimulates mRNA to synthesize specific proteins and enzymes
prednisone
glucocorticoid: stimulates mRNA to synthesize specific proteins and enzymes
Febuxostat
non purine xanthine oxidase inhibitor
Allopurinol
purine xanthine oxidase inhibitor
oxypurinol
active metabolite of allopurinol, not FDA approved, but compassionate use allowed
probenecid
blocks reabsorption of urate w/in kidneys
sulfinpyrazone
blocks reabsorption of urate w/in kidneys
losartan
Angiotensin II receptor antagonist, modest uricosuric effects
pegloticase
pegylated recombinant uricase, converts uric acid to more water soluble allantoin
rasburicase
recombinant uricase, converts uric acid to more water soluble allantoin