Goljan Endocrine

Front 1

Clinical findings of hypoathalmic dysfunction?

Back 1

Central diabetes insipidus, secondary hypopituiatrism, hyperprolactinemia (decreased dopamine), precocious puberty (boys midline hamartoma), visual disturbances. mass effects, Kallman's syndroem

Front 2

Clinical findings of pineal gland tumor:

Back 2

paralysis of upward conjugate gaze (Parinaud's syndrome), ostructive hydrocephalius (compression of the aqueduct of sylvius in 3rd ventricle

Front 3

Tumors of MEN I

Back 3

pituiary ADENOMA (MOST COMMON CAUSE OF HYPOPITUITARISM), hyperparathyroidism, pancreatic tumors

Front 4

Craniopharygioma

Back 4

most common cause of hypopituiatrism in kids, benign pituitary tumor from Rathke's pouch remnants

Front 5

Pituiatary apoplexy

Back 5

sudden onset of dysfunction, d/t hemorhage/infarction f preexisting adenoma, clincial onset of headache, visual disturbances, hormone dysfunction (includes Sheehan's syndrome)

Front 6

Empty Sell syndrome

Back 6

Anatomic defect, Fills up the sella with CSFincrease in pressure on pituiary causes it to flatten out, pituitary hypofunction

Front 7

Prolactinoma

Back 7

most common pituitary tumor, amenorhea and glactorhea in women, impotence and headache in men, > 200 ng/mL serum prolactin levels

Front 8

Alterations in thyroid binding globulin:

Back 8

alter total serum T4 no effect on free T4 or TSH

Front 9

Findings of acute thyroiditis

Back 9

typically bacterial infection, fever, tender gland with paingul adenoppathy, thyroptocicosis from gland destruction, decreased radioidodide uptake

Front 10

Subacute granulomatous thyoriditis

Back 10

d/t viral infection, occurs more often in women, granuomatous inflammaiton and multinucleated giant cells, paingul thyroid, no cervicaladenopathy, preceded by URI, permanent hypothyroisim is uncommon

Front 11

Reidel's thyroiditis

Back 11

fibrous tissue replacement and fibrosis of land, associated with other sclerosing conditions

Front 12

Subacte painless lymphocytic thyroiditis

Back 12

autoimmune develops post partum, glands lack follicles, abrupt thyrotoxicosiss (painless), progresses to hypothytoidism, antimicrosomal antibodies

Front 13

Pt has tacharrhymias, high body temp, shock and coma, tx?

Back 13

B-blocker and thioamides (thyroid storm)

Front 14

Papillary adenocarcinoma

Back 14

most common endocrine cancer, 2nd or 3rd decdes d/t radiation exposure, Psammonia bodies (calcified cancer cells), lymph invasion