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12 Cards in this Set

  • Front
  • Back

What are glial cells?

Non-neural cells


CNS and PNS

Glial cells in CNS?

Oligodendrocytes


Astrocytes


Ependymal cells


Microglia

Glial cells in PNS?

Schwann cells


Satellite cells

Oligodendrocytes


Mainfunction?

Support and insulation to axons in CNS


Creates myelin sheaths


One oligodendrocyte - 50 axons


One oligodendrocyte, one section for several adjacent axons



Oligondendrocyte


Injury

Multiple sclerosis


Leukodystrophy - degeneration of white brain matter

Astrocyte, function?

Structural - physical structure of brain


Glycogen fuel reserve buffer - glucogenesis


Metabolic support - provide neurons with nutrients


Glucose sensing -


Transmitter uptake and release


Regulation of ion concentration in extracellular space


Modulation of synaptic transmission


Vasomodultion - blood flow


Promotes myelin activity


Nervous system repair - glial scar


Astrocyte subdivisions?

Fibrous astrocyte


Protoplasmic astrocyte


Ependyma, function?

CNS


Production of cerebrospinal fluid


Neuroepithelial lining of ventricular system CNSProduction of cerebrospinal fluidReservoir of neuroregenerationLink to astrocytesCilia


Reservoir of neuroregeneration



Link to astrocytes


Cilia


Fibrous astrocytes

Prevalent among myelinated nervefibres in white matter of CNS


Fibrils in cytoplasm


Feet at capillaries!

Protoplasmic astrocytes

Occur in gray matter of CNS


Microglia, function?

Resident macrophage


Active immune defense of CNS


Unique K+ channel


Highly adaptive



Blood-brain barrier

BBB


Semipermeable


Formed by endothelial cells