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18 Cards in this Set

  • Front
  • Back
Name all the Hep drugs we learned in the pharm lecture?
Adefovir, Entecavir, Interferon, Lamivudine, PEG-interferon, Telbivudine, Tenofovir
Name the nucleside Hep drugs...
1. Lamivudine
2. Entecavir
3. Telbivudine
4. Ribavirin
What are the nucleotide Hep drugs?
1. Adefovir
2. Tenofovir
What are the cytokine Hep drugs?
1. Interferon
2. PEG- interferon
1. Which Hep drug w/o food?

2. Which hep drug has to be with food? Nuance to this?
1. Entecavir

2. Ribavirin but it can never be given alone!
Which drug would you probably not use for renal dysfunction?

Which causes thinning of bones?(osteoporsis)
- 1. Adefovir

2. tenofovir
Which drugs may cause neurologic /psychiatric symptoms?
cytokines-
Interferon and PEG- interferon
What two drugs are cautioned against using with renal toxic agents?
Adefovir and Tenofovir
What are the two drugs of choice for HEP-B?
1. Entecavir
2. Tenofovir
What is the drugs of choice for Hep-C treatment?
PEG- interferon and Ribavirin
Name all the drugs used for Hepatitis...
A, E, I, L, P, R, T, T
8 types
What drug develops rapid resistance and myopathy?

When would you use it?
Telbivudine
- only if nothing else works
Which drug has the most side effects and when are these side effects most likely?
PEG-interferon 80% show SE's
flulike- 2-8 hrs after first use
first month- psych behavior (depression)
What two hep drugs are prodrugs?

Which drug interacts with anti-HIV meds making them not work?
Adefovir, and Tenofovir

- Ribavirin
Which Hep drugs have anti-HIV activity?
Can they be used for HIV and HEP?
If using for HIV and HEP have to also use drugs just for HIV
- TEAL
- tenofovir, entecavir, adefovir, lamivudine
Which drug is twice a day?

Which drug is almost unable to be cleared if you have liver problems?
Ribavirin

- Interferon
The following adverse effects are from which hep drug?
a. Renal (SrCR and PO4) toxicity and no osteo effects
b. myopathy and rapid resistance developement
a. adefovir
b. telbivudine
What is the difference between Interferon and pegylated interferon for HEP treatment?
Peg- has longer half life and is slightly better for your liver