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44 Cards in this Set

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What causes amoebic dysentery?

Most common dissemination?

S/S of acute and chronic?

What stage is often ingested?
Entamoeba histolytica

Liver abscess

acute: dysentery, abd pain, mucosal necrosis
chronic: acute S/S, + quadrinucleate cysts in feces

cysts
E. histolytica:
Characteristic histology finding?

Diagnostic requirement?

Treatment?
NO cysts, trophozoites + RBC's
3 stool tests - trophozoites + RBC's

mild: iodoquinol,paromomycin
moderate: Met, tinidazole
Severe/extraintestinal: *Met*, dehydroemetine
Giardiasis:
Organism?

Prevalence is high with _________.


Acute S/S?

Treatment?
Giardia intestinalis- "beaver fever"- not "Beiber fever" man if i ever saw t aht kid i would just punch him

poor water sanitation

explosive diarrhea, abd pain, smelly farts, greasy stools

DOC is Metronidazole, Oral rehydration
Spore forming protozoa: *SPORE IN NAME*

Organisms?

S/S?

Transmission?

Who is mostly affected?
Cryptosporidium, Isospora/Cyclospora, Microsporidia

S/S: acute diarrhea in normal, chronic in immunocompromised

Transmission: fecal-oral
Usually affects immunocompromised
- well hydrated "Flagyl"- metronidazole
Cryptosporidiosis:
Infects what hosts?

S/S of Isospora and Cyclospora?

Lab Dx for these organisms?

Tx for C. parvum? Iso/Cyclo?
Crypto - cattle, livestock, *dogs*

Iso/Cyclo S/S: flu-like symptoms

Lab Dx: modified acid-fast stain

Tx for C. parvum: none, need to maintain immunity
Tx for Iso/Cyclo: Bactrim
Most common human helminthic infection?

Route of infection?

Manifestations?

DOC for Ascaris?
Ascaris lumbricoides

Ingestion, penetrate alveolar wall, ascend bronchi --> throat, swallowed

appendicitis, eosinophilic pneumonitis (Loeffler's Syndrome)

Albendazole
Hookworm found in US?

Route of infection?

S/S?

DOC?
Necator americanus

filariform larva --> skin --> lungs --> swallowed --> intestine --> maturation, eggs in feces

+anemia, malnutrition, edema

DOC: infants - pyrantel pamoate, adults - meben/alben
Which helminth completes its entire life cycle in humans?
(Strong with the force this one is)

Two life cycles?

S/S?

DOC?
Strongyloides stercoralis

Free-living - fecal oral
Parasitic - skin --> lungs --> throat --> swallowed

S/S: ground itch, pneumonitis, ulcers

DOC: albendazole, ivermectin
Whipworm:
2nd most common US whipworm?

Route of infection?

Egg shape?

DOC?
Trichuris trichiura

fecal-oral

Egg: barrel shape, 2 polar plugs

DOC: mebendazole, albendazole
Pinworms:
Organism?

Why is this worm's habitat unique?

Route of infection?

Dx? (Got any tape)?

DOC?
Enterobius vermicularis

common in temperate regions, NOT TROPICAL

ROI: eggs hatch in perianal region, larva into GI tract

Dx: tape on ass, find eggs

DOC: albendazole
Roundworms: (pets)
Commonly found in what animals?

Usually affects what organ?

Tx?

Prevention?
Dogs, cats

eye is usually affected (toxocara)

Tx: Albendazole, mebendazole

Prevention: treat pets, cover sandboxes, cook crustaceans well
Trematodes - Flatworms
3 Schistosomiasis species? Where are they found?

Larval stage in what animals?

What organs do they like?

DOC?
mansoni - S. America, Arabia, Africa
haemotobium - Africa, India
japonicum - Asia

fresh water snails

M - liver portal system, H - bladder, K - sup. mesenteric veins

DOC - Praziquantel
Tapeworms:
Host for: T. solium, T saginata, D. latum:

body structure?

Route of infection?

S/S?

DOC?
T. solium: pigs
T. saginata: cattle
D. latum: fish

scolex, proglottids + eggs

ROI: under-cooked meat

S/S: usually none, sometimes appendicitis, B12 deficiency

DOC: Praziquantel
Echinococcus:
Unique about life cycle?

Characteristic manifestation?
Humans aren't really involved in life cycle, but can ingest the adult organism and be infected

Hydatid cysts
Balantidiosis:
Organism?

Route of infection?

What animal has 20-100% prevalence?
Balantidium coli

ingestion of cysts

Pigs
What helminth can migrate to your CNS and cause calcified cysts?
Cysticercosis-brain
caused by T. solium
Pt. comes in to the clinic after he went crazy and ate his dog's poo about 15 years ago and felt he should confess... you feel a mass on his liver. turns out he's got them all over his liver... Dx? Tx?
Dx: Echinococcus granulosus (hydatidosis)
Tx: surgical removal of hydatid cysts, give Praziquantel w/ albendazole or meb)
Pt. presents w/ severe bloody diarrhea and RUQ pain after coming back from swimming tour in third-world countries. Stool sample reveals cysts w/ 4 nuclei and trophozoites containing RBC's. Dx? Tx?
Dx: E. histolytica (amebiasis)
Tx: Metronidazole followed by paromomycin
Pt. presents w/ foul-smelling EXPLOSIVE diarrhea, bloating. Hx reveals he went hiking a week ago and drank from the beautiful streams. Dx? Tx?
Dx: Giardiasis
Tx: Metronidazole or Tinidazole
Immunocompromised Pt. presents w/ severe watery diarrhea after visiting a local farm to pet the animals. Stool sample reveals cysts on acid-fast stain. Dx? Tx?
Dx: cryptosporidium
Tx: symptomatic
Pt. presents w/ appendicitis and eosinophilic pneumonitis. They got back from a tropical year-long trip. Stool sample reveals ovoid eggs. Nothing else remarkable. Dx? Tx?
Dx: Ascaris lumbricoides
Tx: Albendazole or Mebendazole
8-yr-old female presents w/ diarrhea, wt loss, anemia, distended abdomen, and itchy rash on planter surface of L foot. Stool sample reveals some eggs. Dx? Tx?
Dx: Hookworm (Necator americanus)... be careful as larvae look like strongyloides
Tx: Albendazole or Mebendazole
Pt. presents w/ steatorrhea, vomiting, malabsorption syndrome, skin lesion on foot. Stool sample was negative, but enterotest (string test) was positive. Dx? Tx?
Dx: Strongyloides stercoralis
Tx: Ivermectin po
10-yr-old male presents w/ slightly bloody diarrhea, lower abdominal pain, tenesmus, and rectal prolapse. Stool sample reveals barrel-shaped eggs. Dx? Tx?
Dx: whipworm (trichuris trichuria)
Tx: Mebendazole
7-yr-old male presents w/ "my booty itch at night". You pull out the scotch tape b/c you suspect what? Tx?
Dx: Pinworms (enterobius vermicularis)
Tx: Mebendazole
Little child presents w/ unilateral cataracts and retinitis. He enjoys playing w/ "scruffy the dog" all day everyday during the summer and sharing food with him. Found some eggs in the stool. Dx? Tx?
Dx: Toxocara canis (or cati)
Tx: Albendazole or Mebendazole
Which Schistosoma species lives in your venous plexuses of the bladder?
S. hematobium
Which schistosoma species lives in your portal system of the liver and small venules of the colon and lower ileum?
S. mansoni
Which schistosoma species lives in your superior mesenteric veins draining the SI?
japonicum
Pt. presents w/ inflammation of spleen and liver, fever, chills, abd pain. He just got back from spending a year in the carribean. Stool revealed eggs w/ an obliquely oriented "tail." Dx? Tx?
Dx: schistosomiasis (mansoni)
Tx: Praziquantel
Carrier state common in tropical countries often without disease
• Causes dysentery and GI bleeding in susceptible hosts
• May mimic GI carcinoma
-perforate mucosa and disseminate widely
Entamoeba histolytica
This is mostly found in the SE US and can penetrate the foot. How much blood does it drink?
What positive can we come up with on these?
What sign may we see in myocardium?
hookworm - Necator Americanus
- drinks .2ml of blood causes anemia
- secrete anticoagulant and do not reproduce inside
- "tiger stripes" in myocardium
What is the flag sign in hair and what bug is it associated with?
- due to anemia possibly caused by necator Americanus (hook worm)
What type of worm do you do the "scotch tape" test for?
Pinworm (enterobius vermicularis)
most common cause of epileptic seizures from people that come from tropics
cysticercosis
"Beaver Fever" with severe non‐invasive diarrhea after drinking water fresh from rocky mountain stream
Giardia lamblia
Larvae hatch in the gut, then migrate through tissue to the lung – are swallowed, then mature in the gut
• Eggs are passed through in the feces, where they may infect another human via fecal‐oral
contamination
Ascaris lumbricoides- intestinal round worms
larvae hatch in small intestine and make way into the cecum where they live as adults which may cause anal- prolapse
Whipworm – Trichuris trichiuria
Brain cysts and seizures think...
taenia solium (cysticercosis)
Liver cysts think
echinococcus granulosus
Portal hypertension thinking (parasite)

hematuria, bladder cancer
schistosoma mansoni

schistosoma haematobium
Microcytic anemia
necator americanus
Perianal pruritus
enterobius
Name the three parasites that migrate to lungs are coughed up and swallowed into the GI to grow to adults...
How does each of the three cause problems?
Diagnosed?
1. Ascaris lumbricoides (egg/eosinophils in feces)- eggs injected
2. Necator Americanus (eggs eosinophil in feces)- larvae penetrate skin
3. Strongyloides stercorous (filiarform passed)- larvae penetrate skin