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77 Cards in this Set

  • Front
  • Back
What is cheiloschisis and palatochisis?
Cleft lip and cleft palate.



Most common in brachycephalics.

What is -




  1. Agnathia
  2. Brachygnathia
  3. Prognathia




  1. Absence of jaw
  2. Short jaw
  3. Long jaw



Dog and pig.




Superior = maxilla, inferior = mandible

What is -




  1. Aglossy
  2. Microglossy
  3. Macroglossy
  1. Absence of tongue
  2. Small tongue
  3. Big tongue



Rare.

What are causes of atrophy?

  • Lack of innervation - lesion on nerve
  • Starvation
  • Lack of blood supply
  • Disuse
  • Pressure e.g. neoplasia
  • Loss of hormonal stimulation

Describe circulatory disorders. (general)

Pallor - due to


  • anaemia
  • heart failure



Cyanosis - dark red/blue mucosa, tissues near surface starved of oxygen. Due to



  • Uraemia
  • Nitrate poisoning
  • Bluetongue - orbivirus



Petechiae and ecchymoses- due to



  • clotting defects
  • toxicities
  • septicaemia

Describe gingivitis.

Inflammation of gingiva - dog and cat.





  • Opportunistic bacteria
  • Immunodeficiency (FIV)
  • Poor oral hygiene
  • Gingival trauma



Often leads to periodontitis.

Describe periodontitis.

Inflammation of tissues surrounding teeth. Common in dogs and cats, caused by -



  • Bacterial plaque on lateral tooth



Progression associated with



  • Pocket formation in g. sulcus
  • loose/loss of tooth
  • fistulae

Describe necrobacillosis.

Cause of necrotising stomatitis in lambs and piglets.




Caused by Fusobacterium necrophorum - invades mucosal surfaces that are damaged then produce toxins causing a coagulative necrosis.




Calves get diptheria or hepatic necrosis too.

Describe Wooden Tongue.

Cattle - Actinobacillus lignieresi - normal flora




Can cause abscesses, pyogranulomas, fibrosis.

Describe Bluetongue.

Orbivirus - mainly sheep, spread by Cullicoides spp. inducing viraemia and infecting endothelium.




Causes -


  • endothelial damage
  • microthrombi
  • haemorrhages
  • ischaemic necrosis



Findings -


  • early - hyperaemia/oedema of oral/nasal mucosa (+cyanosis of tongue)
  • Late - ischaemic necrosis (infarction) of oral epithelium

Describe FMD.

Apthovirus - cattle, swine, sheep, mild zoonotic risk.




Aerogenic transmission




Replicates in oral/pharyngeal mucosa → 1ry lesions → viraemia → 2ry lesions (aphthae)




Aphthae found on tongue, lips, palate, skin @ coronary band by interdigital space, and sparsely haired areas e.g. ruminal mucosa




→ epithelium → ballooning degeneration → detach → oedema and fibrin fills space (vesicle) → vesicles coalesce (bullae) → erosions/ulcers

Describe infectious vesicular stomatitis.

Vesiculovirus - horse, cattle, swine - zoonotic risk




Infection via skin/mucosal wounds




Lesions on mucosa identical to FMD

Describe swine vesicular disease.

Enterovirus - pigs only.




Skin/oral mucosal lesions similar to FMD.

Describe erosive and ulcerative stomatitis.

BVD-MD (mucosal disease)



  • pestivirus
  • Erosions and flat ulcers
  • Oral mucosa, muzzle, oesophagus, rumen, abomasum, intestine
  • Seen in PIs



Bovine Malignant Catarrhal Fever



  • OHV-2
  • Sporadic in cattle, sometimes swine
  • Erosions on oral mucosa, oesophagus, abomasum, intestine
  • Associated w/ conjunctivitis and keratitis

Describe Candidiasis.

Candida albicans - Fungi




Mainly in young, immunocompromised or when hygiene is poor.




Intestinal CS if in GIT. Thickened mucosa of oesophagus, tongue, rumen.

What are the main parasites of mucosa?

  1. Cysticercus cellulosae - lingual m. of pigs - larvae of T. solium
  2. Cysticercus bovis - lingual m. cattle, larvae of T. saginata
  3. Trichinella spiralis - pig

Describe mucosa viral papillomas.


  • Dogs, cattle, rabbits - younger animals
  • Oral and labial mucosa
  • Papillomavirus
  • Spontaneous regression likely

Describe an epulides.


  • Mainly dogs, cats too
  • Benign neoplasm of periodontal ligament/CT
  • Fibromatous - expansile, no invasion, fibroblasts and collagen
  • Ossifying - fibromatous w/bone formation
  • Acanthomatous - stratified epithelium which invades underlying bone

Describe oral squamous cell carcinoma.

Most common malignant neoplasm in oral cavity of cats, 2nd most in dogs. Rare in other species.




Often invade adjacent ST, m., bone




Metastasise to regional LNs.

Describe tonsillar squamous cell carcinoma.


  • Dogs
  • Early metastasis to regional LNs - metastases bigger than 1ry tumour
  • Distant metastases 60% cases
  • Pearl formation on histology

Describe melanoma.


  • From melanocytes w/ partially pigmented mucosa
  • Dogs - most common malig oral neoplasm
  • Early metastases → lungs and SM LNs
  • Melanotic or amelanotic (rare)

Describe oral fibrosarcoma.


  • From CT of oral mucosa
  • Cats - 2nd most frequent malig oral neoplasm
  • Invades underlying CT, m., bone
  • Widespread metastases possible
  • Cannot differentiate from SCC - both bad prognosis

Describe ameloblastoma.


  • Odontogenic
  • Arise deep in mandible/maxilla
  • Solid/cystic
  • Teeth loose or missing

Describe odontoma.

  • Odontogenic

  • dental malformation rather than neoplasm

  • Complex (all normal tissue but malformed)

  • Or compound (tooth-like tissue, abnormally arranged)

What is sialoadenitis?

Inflammation of the salivary gland

What is sialoliths?

Salivary calculi in duct or gland due to chronic inflammation or FBs

What is ranulae?

Cysts in sublingual duct - in frenulum

What is sequalae for obstruction, strictures and compression of the oesophagus?

  • Dysphagia
  • Tympanites (swelling of abdomen)
  • Diverticulum formation
  • Rupture
  • Regurg and aspiration pneumonia

Describe the 2 types of megaoesophagus.

Congenital - dogs and cats



  • Defect in reflex coordinating oesophageal function
  • Inherited
  • great danes, GSDs, Irish Setters



Acquired - adult dogs



  • 2ry to any disorder that disrupts neural reflex of swallowing
  • e.g. myaesthenia gravis - autoAb to nic.ACh receptors = general m. weakness
  • also, botulism, lead,neoplasia

What is dysautomnia?

Grass sickness (horses) and Key-Gaskell syndrome (dogs, cats).




Abnormal function of para/sympathetic ns.




There is ↓ number of autonomic ganglia

Describe oesophagitis.

Inflammation of oesophagus.




Occurs with infectious diseases -



  • BDV-MD
  • MCF
  • IBR

Or with chemical reflux -



  • Gastric acid
  • Pepsin

What is the parasite of the oesophagus?

Spirocerca lupi.




Dogs in tropics - IH beetles




L3 enter subintima of gastric a. and aorta → caudal thoracic area → oesophagus → adult →perforate oesphagus causing granulomatous oesophagitis → sarcomas (osteo/fibro)

Describe ruminal tympany.

xs gas distends rumen (CH4, CO2) normal eructations impaired.



  • Frothy - gas in small bubbles and cannot escape with eructation - caused by legumes 2-3d post-ingestion (clover)
  • 2ry/free gas - less common, due to obstruction of oesophagus/pharynx

Describe ruminal acidosis, rumenitis and ulcers.

Successive stages - associated w/change in diet mainly seen in high production cows





  • Carb overload
  • ↑ production of VFAs
  • atony
  • ↓ in rumen pH
  • Lactobacillus acidophilus proliferates
  • pH <4.5 = die

Survivors will get 2ry infection with necrobacillosis and mycotic rumenitis

Describe traumatic reticulitis.

Cattle - swallowing foreign material e.g. nails or wire.




The reticulum is perforated cranially, puncturing the heart causing a chronic pericarditis.

Describe gastric dilation and volvulus.

Dogs (GD, SB, IS, WH, BH - deep chested), horses or pigs.




Dilation often followed by volvulus (360 degree clockwise spin- caudal aspect).




Pylorus, terminal duodenum + spleen move too → occlusion of oesophagus.




Sequalae -



  • Gastric haemorrhagic infarction
  • ↓ CO
  • Arterial hypotension
  • ↓ renal function
  • shock

Describe abomasal displacement.

Displaced to anterior abdomen, usually to left side.




Usually older cows.




Without replacement, haemorrhagic infarction.

What is abnormal content of the stomach?

  • Foreign material - pica
  • Zootrichobezoars - impacted hair balls in abomasum of calves, stomach of angora rabbits. Possible rupture
  • Gastrolithes - horses + reptiles - stomach/gizzard stones for grinding

Describe acute cattarhal gastritis.

Reddening and thickening of mucosa, ↑ mucous production




Caused by poisons and infectious diseases e.g. Helicobacter

Describe acute haemorrhagic gastritis.

H+ (free blood, no inflammation).




Seen with poisons, infectious disease (Erisipelas) and NSAIDs.

Describe mucosal haemorrhage.

Occurs w/uraemia mainly.



  • Endoth degen + necrosis
  • Thrombosis
  • Infarction
  • Coagulative necrosis
  • Haemorrhage
  • Neutrophil infiltration
  • Mineralisation

Also occurs w/hog cholera, anthrax and lepto.

What is (fibrino) necrotising gastritis seen with?

mycotic infection → mucosal destruction

Describe eosinophilic gastritis.

Eosinophilic inflam infiltrate from helminth larvae (dogs) - Toxacara canis.

Describe gastric ulcers in cattle.

Calves, dairy cows, yearlings.




Mainly in pylorus associated w/environmental conditions e.g. transport stress, diet changes

Describe gastric ulcers in swine.

Occurs in squamous portion.




Unknown cause - associated w/hyperacidity and finely ground grain

Describe gastric ulcers in foals.

Non-glandular portion due to mechanical trauma by Gastrophilus intestinalis.

Describe gastric ulcers in dogs and cats.

Pylorus and proximal duodenum.




Associated w/mast cell tumours

What is the sequalae to gastric ulcers?

Vascular erosion (h+ → anaemia) and perforation → subsequent peritonitis.

Describe gastric rupture.

Most common in horses due to dilation. Rarely due to trauma.




Die within hours due to intoxication and shock.

What are the two neoplasms of the stomach?

Adenocarcinoma and squamous cell carcinoma.

Describe gastric adenocarcinoma.

most common gastric neoplasm in dogs.




Mostly arise from less curvature.




Diffuse, invasive growth in stomach wall and superficial ulcers.




Common metastases to regional LNs, liver and lungs.

Describe gastric squamous cell carcinoma.

Arise from squamous epithelium. More common in horse, pigs.




Invasive growth, occasional lymphatic invasion/metastases.

What is intestinal atresia?

Either complete lack of some part of the intestine or blind ends present.




Most common in calves - ileum/colon

What is anal or rectal atresia?

failure of development of anal opening




Piglets

What is megacolon?

Dog, cat, horse, swine.




Aplasia of neurons in LI mesenteric ganglia → lack of bowel movement.

Describe diaphragmatic herniation.

Displacement of omentum, stomach, spleen, SI and liver into thoracic cavity




Pulmonary atelecstasis due to compression.

Describe intussusception.

Telescoping.




Caused by hyperactive bowel movements.




Mainly SI in dogs (CPV, CDV)




Mainly ileum into caecum in horses (tapeworm)

Describe volvulus of intestines.

Twist @ root of mesentery.




Usually jejunum/ileum.




Can also be caused by intestine wrapped around pedunculated lipoma.

What is the result of intussusception and volvulus?


  • vv. occluded, aa. not
  • hypoxia
  • ↑BP (congestion)
  • haemorrhage
  • necrosis

Why does d+ result from enteritis?

  1. Maldigestion
  2. Malabsorption - ↓ area due to loss of villi
  3. Hypersecretion - of electrolytes due to enterotoxins
  4. ↑ motility

Describe catarrhal enteritis and possible causes.

Death of epithelium, hyperaemia, lymphocytic infiltration.




Viral causes



  • Coronavirus - calves, piglets, puppies
  • Rotavirus - lethal in piglets and calves
  • CPV-2



Bacterial causes



  • ETEC - calves, lambs, piglets <1wo. Adhere to enterocytes, produces toxins → secretory d+
  • EPEC - destroys microvilli
  • Oedema disease (STEC) - pigs. Oedema in eyelids, nose, stomach wall, mesenteric LNs
  • Coli septicaemia - newborns. Occasionally enteritis, otherwise typical sepsis

Describe Salmonellosis.

Cause fibrino-necrotising enteritis in ruminants, swine, horses.




Young



  • peracute (septicaemia)
  • acute (cat/fibr enteritis)
  • chronic (fibr-necr typhlocolitis)



Adult horses



  • fibrino-necrotising/haemorrhagic typhlocolitis (S.typhimurium)



Swine



  • Necrotising enteritis (S.cholerasuis)
  • ulcerative proctitis (S. typhimurium)






What is a viral cause of fibrino-necrotising enteritis.

Fibrin exudate - Classic swine fever - pestivirus.




Acute colitis and bouton development in colon (focal FNC). Sometimes diffuse.

Describe Porcine Proliferative Enteritis.

Fibrino-necrotising enteritis - fibrin exudate.




  • Lawsoniaintracellularis
  • In cryptsof ileum, also caecum and colon
  • Post-weaningpigs
  • Mucosalhyperplasia
  • Intestinaladenomatosis - foals, lambs, puppies
  • Four disease forms - adenomatosis, proliferative haemorrhagic enteropathy, necrotic enteritis and terminal ileitis

Describe a cause of granulomatous enteritis.

Paratuberculosis - Johne's.




Mycobacterium avium spp. paratuberculosis.




Untreatable d+ → death through emaciation.




Bacteria → macrophages and GALT - jejunum and ileum.




Granulomatous in cattle, catarrhal in sheep and goats.

Describe IBD.

Dogs and cats - most common cause of v+ and d+.




Severe in Basenjis - immunopathological aetiology.




Progression into intestinal lymphosarcoma in cats possibly.

What is malabsorption syndrome?

Failure to absorb nutrients, characterised by -



  • Persistant v+, d+
  • Weight loss
  • Steatorrhoea

Causes -



  • Pancreatic insufficiency
  • Protein losing enteropathy



Will see -



  • lipid granulomas
  • lymphangiectasia (dilation of LNs)

When does active hyperaemia of intestines occur?

During digestion

When does passive hyperaemia, oedema, infarction, occur in the intestines?

  • Misalignment - volvulus, torsion

When does intestinal ischaemia occur?

  • Shock - dog
  • Misalignment
  • Thrombosis of intestinal aa. - emboli
  • Haemomelasma ilei - dark grey/black discolourations, elevated in ileum, due to thrombosis of small aa.

What are the intestinal coccidia of different species?

  • Cattle - Eimeria bovis, E. zuerni
  • Sheep - E. bakuensis, E. ansata, E. ovinoidalis
  • Goat - E. arloingi
  • Horse - E. leuckarti
  • Swine - Isospora suis

What are the main intestinal cestodes?

  • Ruminants - Moniezia expansa, M. benedeni
  • Horses - Ano. perfoliata, A. magna
  • Dog - Diplyd. caninum, T. pisiformis, T. hydatigena, E. granulosus, E. multilocularis, T. multiceps, T. ovis, Mesocestoides lineatus
  • Cat - T. taeniaeformis, Diplyd. caninum

What are the main intestinal nematodes?

  • Oesophagostomum spp - cattle (O. radiatum), S+G (O. columbianum, O.venulosum) and swine (O. dentatum) - cause lymphatic follicle ulcers



Horses -



  • Large strongyles - S. equinus, S. edentatus, S.vulgaris
  • Small strongyles - cyathostomes

What are the 4 neoplasms of the intestines?

  1. Colorectal polyps (dogs)
  2. Adenocarcinoma
  3. Adenocarcinoma of apocrine glands of anal sac
  4. Malignant lymphoma

Describe adenocarcinoma of intestines.

Sheep and horses (SI), dogs (rectum).




Often huge fibrous tissue proliferation and metastases to LNs and local adjacent parenchyma (prostate for dog).




Contact metastases possible.

Describe adenocarcinoma of apocrine glands of anal sac.

Dogs with paraneoplastic syndrome-associated hypercalcaemia.




Metastases to LNs.

Describe malignant lymphoma of intestines.

Mainly cats and dogs. Poss horse+cattle.




Diffuse/nodular thickening of intestine wall.




Cats - mainly older