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28 Cards in this Set
- Front
- Back
Functions of GI System
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Ingestion of nutrients
Digestion of nutrients Absorption of nutrients Elimination of wastes Protection of immunity |
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GI Mucous Cells
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Rapid turnover q 3-4 days
More rapid during stress Tissue erodes from inside |
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Pathogens escape from inside gut structures into lymph vessels, blood vessels, and abdominal cavity
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GI Translocation
Source of MODS |
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GI Alterations Clinical Manifestations
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Abd pain
Anorexia Constipation Diarrhea Vomiting Bleeding |
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>500 mls water stool x 2 days
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Diarrhea
Inconsisten clinical definition |
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Diarrhea Etiology
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Enzyme deficiencies
Intake of highly osmotic substances- high carb intake Infection Ischemia Fecal Impaction |
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Clinical Manifestations - Diarrhea
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Fluid Loss
Weight loss Electrolyte imbalance Discomfort |
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What laboratory test can indicate GI bleeding before onset of outward signs?
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BUN
Digestion of blood proteins Nitrogen end-product of protein metabolism Increased serum BUN |
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Motility Alterations
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Dysphagia
GERD Hiatal hernia Gastroparesis Pyloric obstruction Intestinal obstruction |
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Stomach paralysis
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Gastroparesis
Acute illness/injury Diabetes mellitus Chronic renal failure Spinal cord injury Neuromuscular disorders |
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Relaxation of lower esophageal sphincter
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GERD
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Intestinal Obstruction
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Small or large intestine
Mechanical vs. Functional Acute r/t mechanical cause Chronic r/t functional |
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Intestinal obstruction etiology
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Hernia
Intussusception Torsion Diverticulosis Tumor Illeus |
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Abnormality of mucosa prevents nutrient uptake in intestine
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Malabsorption syndromes
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Total stomach removal
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Gastrectomy
Loss of food reservoir Dumping syndrome Loss of intrinsic factor |
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Rapid movement of ingested fluid and electrolytes into small bowel
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Dumping syndrome
Cramping abd pain Diarrhea Weigh reduction procedures provoke this |
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Reflux of stomach contents into esophagus
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Esophagitis
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GERD
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Pain- so bad they go to hospital thinking they're having a heart attack
Athma trigger If left untreated: Barrett esophague - precursor for esophageal cancer |
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Gastritis
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Inflammation of lining of stomach
Acute Chronic |
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Causes of Gastritis
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Aspirin
NSAIDS H. Pylori Alcohol ingestion Smoking Physiologic stress |
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Acute Gastritis
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Last a few hours to a few days
Self-limiting Expect complete healing of mucosa Remove cause Treat symptoms |
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Chronic Gastritis
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Repeated episodes
Increases with age Chronic exposure to causative agent(s) |
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Peptic Ulcer Disease (PUD)
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Ulceration of GI tract due to acid-pepsin activity
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Clinical Manifestations of PUD
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Pain
Often relieved by food/antacids Occult GI bleeding Dark stools |
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Chron Disease
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Inflammation, swelling, thickening
Can occur anywhere in the GI tract All layers of bowel wall common Bowel scarring, stiff Malabsorption |
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Etiology- Chron's
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Unknown
Familial Stress |
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Ulcerative Colitis
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Major diff from Chron's - only involves mucosal layer of colon
Inflammation Sloughing of tissue |
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Etiology- UC
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Familial
Stress Emotional triggers |